- Suchergebnis für P62837
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Zu "P62837" wurden 19 Artikel gefunden!
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Artikelnummer: BPS-80314-1
Human UbcH5a also known as UBE2D2 (GenBank Accession No. U39317.1), amino-acids 2-end, with N-terminal His tag, MW=18 kDa, expressed in an E. coli expression system.
Schlagworte: | PUBC1, UBE2D2, Ubiquitin-protein ligase D2, Ubiquitin carrier protein D2, E2 ubiquitin-conjugating enzyme D2,... |
Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 18 kD |
ab 407,00 €
Artikelnummer: SBB-CE0027-C100
UBE2D2 (UbcH5b) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D2 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D2-Ub thioester. UBE2D2 is capable of...
Schlagworte: | Ubiquitin-conjugating Enzyme H5b, PUBC1, UBC5B, Ubiquitin-protein Ligase D2, p53-regulated Ubiquitin-conjugating Enzyme 1 |
Anwendung: | Assays |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 17 kD |
396,00 €
Artikelnummer: BPS-79896
UBCH5b (UBE2D2) is an E2 conjugating ubiquitin protein that functions in the ubiquitination of the tumor-suppressor protein p53. It is a promising drug target in cancer immunotherapy. It utilizes biotin-labeled Ubiquitin and a terbium-labeled antibody recognizing the His-tagged UBCH5b protein to complete the TR-FRET...
Schlagworte: | PUBC1, UBE2D2, Ubiquitin-protein ligase D2, Ubiquitin carrier protein D2, E2 ubiquitin-conjugating enzyme D2,... |
Anwendung: | Drug discovery, HTS |
Spezies-Reaktivität: | human |
1.202,00 €
Artikelnummer: ABE-36-3339-100
Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final...
Schlagworte: | Anti-PUBC1, Anti-UBE2D2, Anti-Ubiquitin-protein ligase D2, Anti-Ubiquitin carrier protein D2, Anti-Ubiquitin-conjugating... |
Anwendung: | FC, WB, IF, IHC |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 375,00 €
Artikelnummer: ABE-36-3341-100
Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final...
Schlagworte: | Anti-PUBC1, Anti-UBE2D2, Anti-Ubiquitin-protein ligase D2, Anti-Ubiquitin carrier protein D2, Anti-Ubiquitin-conjugating... |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 375,00 €
Artikelnummer: G-CAB10818.100
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €
Artikelnummer: ATA-HPA003920.100
Protein function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Mediates the selective degradation of short- lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates...
Schlagworte: | Anti-PUBC1, Anti-UBE2D2, Anti-Ubiquitin-protein ligase D2, Anti-Ubiquitin carrier protein D2, Anti-Ubiquitin-conjugating... |
Anwendung: | ICC, IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
421,00 €
Artikelnummer: E-AB-90252.120
Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S...
Schlagworte: | PUBC1, UBE2D2, Ubiquitin-protein ligase D2, Ubiquitin carrier protein D2, E2 ubiquitin-conjugating enzyme D2,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Artikelnummer: ELK-ES3665.100
Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S...
Schlagworte: | Anti-PUBC1, Anti-UBE2D2, Anti-Ubiquitin-protein ligase D2, Anti-Ubiquitin carrier protein D2, Anti-Ubiquitin-conjugating... |
Anwendung: | WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €
Artikelnummer: 043514-APC.200
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s....
Schlagworte: | Anti-PUBC1, Anti-UBE2D2, EC=6.3.2.19, Anti-Ubiquitin-protein ligase D2, Anti-Ubiquitin carrier protein D2,... |
Anwendung: | FLISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
993,00 €
Artikelnummer: 043514-Biotin.200
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s....
Schlagworte: | Anti-PUBC1, Anti-UBE2D2, EC=6.3.2.19, Anti-Ubiquitin-protein ligase D2, Anti-Ubiquitin carrier protein D2,... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
993,00 €
Artikelnummer: 043514-FITC.200
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s....
Schlagworte: | Anti-PUBC1, Anti-UBE2D2, EC=6.3.2.19, Anti-Ubiquitin-protein ligase D2, Anti-Ubiquitin carrier protein D2,... |
Anwendung: | FLISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
993,00 €