Zu "P56817" wurden 59 Artikel gefunden!
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BACE-1, His, Human
Artikelnummer: GSC-Z05067-100
The beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) initiates the generation of amyloid-beta (Abeta), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer's disease (AD). Clinical failures of anti-Abeta therapies in dementia stages suggest that...
| Schlagworte: | BACE1, Memapsin-2, Beta-secretase 1, Aspartyl protease 2, Membrane-associated aspartic protease 2, Beta-site amyloid... |
| Ursprungsart: | human |
| MW: | 49.5 kD |
ab 363,00 €
BACE-1 hFc Chimera, Human
Artikelnummer: GSC-Z05066-100
The beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) initiates the generation of amyloid-beta (Abeta), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer's disease (AD). Clinical failures of anti-Abeta therapies in dementia stages suggest that...
| Schlagworte: | BACE1, Memapsin-2, Beta-secretase 1, Aspartyl protease 2, Membrane-associated aspartic protease 2, Beta-site amyloid... |
| Ursprungsart: | human |
| MW: | 75.2/72.6 kD |
ab 228,00 €
Anti-BACE1 Monoclonal Recombinant Antibody
Artikelnummer: E-AN300071P.100
BACE-1 (beta-site APP cleaving enzyme-1) is an aspartic protease and an integral membrane protein . It is the major beta secretase, and together with the gamma secretase, is responsible for generating the amyloid beta peptide (A beta ) from the amyloid precursor protein (APP) Protein function: Responsible for the...
| Schlagworte: | ASP2, BACE, Asp 2, Memapsin-2, Beta-secretase 1, Aspartyl protease 2, Beta-site APP cleaving enzyme 1, Membrane-associated... |
| Anwendung: | FCM, ICC/IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
462,00 €
Anti-BACE1
Artikelnummer: ARG54921.50
Protein function: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated...
| Schlagworte: | Anti-BACE, Anti-ASP2, Anti-Asp 2, Anti-BACE1, Anti-Memapsin-2, EC=3.4.23.46, Anti-Beta-secretase 1, Anti-Aspartyl protease... |
| Anwendung: | ELISA, WB, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
625,00 €
BACE1 FRET Assay Kit
Artikelnummer: BPS-71656
Bace1 (beta-secretase 1) is an aspartic protease that is involved in the processing of the Amyloid precursor protein (APP). Cleavage of APP by BACE1 followed by gamma-secretase results in beta-amyloid peptide production, which ultimately leads toxic Abeta accumulation. In Alzheimer's disease (AD), it has been widely...
| Schlagworte: | beta-site amyloid precursor protein cleaving enzyme 1, ASP2, |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
834,00 €
Human BACE1 / Beta secretase 1 ELISA Kit
Artikelnummer: G-HUFI02246.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-beta-site APP-Cleaving Enzyme (BACE/Asp2)
Artikelnummer: 200-401-984
Protein function: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated...
| Schlagworte: | Anti-BACE, Anti-ASP2, Anti-Asp 2, Anti-BACE1, Anti-Memapsin-2, EC=3.4.23.46, Anti-Beta-secretase 1, Anti-Aspartyl protease... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
848,00 €
Anti-BACE
Artikelnummer: 200-401-Z18
Anti-BACE Antibody is purified by ion exchange chromatography. Cross reactivity with BACE from other sources has not been determined. Protein function: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and...
| Schlagworte: | Anti-ASP2, Anti-BACE, Anti-Asp 2, Anti-BACE1, Anti-Memapsin-2, EC=3.4.23.46, Anti-Beta-secretase 1, Anti-Aspartyl protease... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
848,00 €
Anti-BACE
Artikelnummer: NSJ-F50757-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase...
| Schlagworte: | Anti-ASP2, Anti-BACE, Anti-Asp 2, Anti-BACE1, Anti-Memapsin-2, EC=3.4.23.46, Anti-Beta-secretase 1, Anti-Aspartyl protease... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-BACE1
Artikelnummer: NSJ-F50758-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a...
| Schlagworte: | Anti-ASP2, Anti-BACE, Anti-Asp 2, Anti-BACE1, Anti-Memapsin-2, EC=3.4.23.46, Anti-Beta-secretase 1, Anti-Aspartyl protease... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-BACE1
Artikelnummer: ARG41146.100
Protein function: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated...
| Schlagworte: | Anti-ASP2, Anti-BACE, Anti-Asp 2, Anti-Memapsin-2, Anti-Beta-secretase 1, Anti-Aspartyl protease 2, Anti-Beta-site APP... |
| Anwendung: | IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Anti-Beta-secretase 1 / Memapsin-2 / BACE1C
Artikelnummer: NSJ-F54840-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the BACE1. The encoded protein, a member of...
| Schlagworte: | Anti-ASP2, Anti-BACE, Anti-Asp 2, Anti-Memapsin-2, Anti-Beta-secretase 1, Anti-Aspartyl protease 2, Anti-Beta-site APP... |
| Anwendung: | IHC (paraffin), FC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €