Zu "P01116" wurden 136 Artikel gefunden!
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Anti-Recombinant KRAS, clone A282
Artikelnummer: E-AN301583L.100
KRAS, a Ras protein, binds GDP/GTP and possesses intrinsic GTPase activity, It plays an important role in the regulation of cell proliferation and in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.
| Schlagworte: | Anti-KRAS, Anti-Ki-Ras, Anti-K-Ras 2, Anti-c-K-ras, Anti-c-Ki-ras, Anti-GTPase KRas, Recombinant KRAS Monoclonal Antibody |
| Anwendung: | WB, IF, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
KRAS, His, Human (G12C)
Artikelnummer: GSC-Z03597-1
The KRAS gene provides instructions for making a protein called K-Ras, part of the RAS/MAPK pathway. The protein relays signals from outside the cell to the cell's nucleus. These signals instruct the cell to grow and divide (proliferate) or to mature and take on specialized functions (differentiate). The K-Ras...
| Schlagworte: | KRAS, Ki-Ras, K-Ras 2, c-K-ras, c-Ki-ras, GTPase KRas |
| Ursprungsart: | human |
| MW: | 23.8 kD |
ab 214,00 €
KRAS, His, Human (G12D)
Artikelnummer: GSC-Z03598-1
The KRAS gene provides instructions for making a protein called K-Ras, part of the RAS/MAPK pathway. The protein relays signals from outside the cell to the cell's nucleus. These signals instruct the cell to grow and divide (proliferate) or to mature and take on specialized functions (differentiate). The K-Ras...
| Schlagworte: | KRAS, Ki-Ras, K-Ras 2, c-K-ras, c-Ki-ras, GTPase KRas |
| Ursprungsart: | human |
| MW: | 23.8 kD |
ab 214,00 €
Anti-Active Ras, monoclonal
Artikelnummer: NB-26909
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the...
| Schlagworte: | Anti-KRAS, Anti-KRAS2 |
| Anwendung: | IP, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
746,00 €
Anti-Ras (G12D), monoclonal
Artikelnummer: NB-26036
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ras (G12D) is one type of Ras missense mutations at the codon 12. Ras protein is a membrane-associated GTPase that regulates cell proliferation, differentiation, and survival. Ras G12D mutation results in...
| Schlagworte: | Anti-KRAS, Anti-KRAS2 |
| Anwendung: | ELISA, WB, IHC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
746,00 €
Anti-Ras (G13D), monoclonal
Artikelnummer: NB-26038
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ras (G13D) is one type of Ras missense mutations at the codon 13. Ras protein is a membrane-associated GTPase that regulates cell proliferation, differentiation, and survival. Ras G13D mutation results in...
| Schlagworte: | Anti-KRAS, Anti-KRAS2 |
| Anwendung: | ELISA, WB, IHC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
746,00 €
A KRAS (G12C), Isoform A, His-Tag, GDP-Loaded
Artikelnummer: BPS-100640-1
Human KRAS, also known as C-K-RAS, CFC2, and K-RAS2A, GenBank Accession No. NM_033360, a.a. 2-186 with G12C mutation and N-terminal His-tag, expressed in an E. coli expression system. MW=23 kDa. KRAS (G12C) His-Tag (BPS Bioscience #100413), is loaded with GDP. Unbound GDP was removed by spin column. Ready for use in...
| Schlagworte: | KRAS, KRAS2, |
| Anwendung: | Nucleotide exchange assay, KRAS(G12C) inhibitors screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 23 kD |
ab 975,00 €
A KRAS (G12C), Isoform A, His-Tag, GppNHp-Loaded
Artikelnummer: BPS-100641-1
Human KRAS, also known as C-K-RAS, CFC2, and K-RAS2A, GenBank Accession No. NM_033360, a.a. 2-186 with G12C mutation and N-terminal His-tag, expressed in an E. coli expression system. MW=23 kDa. KRAS (G12C) His-Tag (BPS Bioscience #100413), is loaded with GppNHp (non-hydrolyzable GTP analog). Unbound GppNHp was...
| Schlagworte: | KRAS, KRAS2, |
| Anwendung: | Nucleotide exchange assay, KRAS(G12C) inhibitors screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 23 kD |
ab 864,00 €
A KRAS (G12D), Isoform A, His-Tag, GDP-Loaded
Artikelnummer: BPS-101312-1
Recombinant human KRAS (GTPase), isoform a, encompassing amino acids 2-186 (end). In this construct the N-terminal end of the protein contains a His-tag (6xHis) followed by an optimal TEV protease target sequence that allows cleavage of the His-tag from the protein (TEV: tobacco etch virus cysteine protease BPS...
| Schlagworte: | KRAS, KRAS2, KRAS (G12D) (His-TEV-2-186)-(GDP) |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 23 kD |
ab 975,00 €
KRAS (G12V), Isoform B, His-Tag, GDP-Loaded
Artikelnummer: BPS-101355-1
Recombinant human RAS (GTPase), isoform b, encompassing amino acids 2-185. This construct contains an N-terminal His-tag (6xHis). The protein also contains mutation of interest G12V. The protein (BPS-100480<) was affinity purified and loaded with GDP. Unbound GDP was removed by spin column.
| Schlagworte: | KRAS, KRAS2, KRAS (G12V) (His-2-185) - (GDP) |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 22 kD |
ab 975,00 €
KRAS (G12V), Isoform B, His-Tag, GppNHp-Loaded
Artikelnummer: BPS-101359-1
Recombinant human RAS (GTPase), isoform b, encompassing amino acids 2-185. This construct contains an N-terminal His-tag (6xHis). The protein also contains mutation of interest G12V. The protein (BPS-100480) was affinity purified and loaded with GppNHp, a non-hydrolyzable GTP analog. Unbound GppNHp was removed by...
| Schlagworte: | KRAS, KRAS2, KRAS (G12V) (His-2-185) - (GppNHp) |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 22 kD |
ab 864,00 €
KRAS (G12D), Isoform A, His-Tag, GppNHp-Loaded Recombinant
Artikelnummer: BPS-101481-1
Recombinant human KRAS (KRAS proto-oncogene GTPase), isoform a, encompassing amino acids 2-186(end). This construct contains an N-terminal His-tag (6xHis) followed by an optimal TEV protease target sequence that allows cleavage of the His-tag from the protein (TEV: tobacco etch virus cysteine protease, BPS-50308)....
| Schlagworte: | KRAS, KRAS2, KRAS (G12D) (His-TEV-2-186(end))-(GppNHp) |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 23 kD |
ab 864,00 €