Zu "O96017" wurden 109 Artikel gefunden!
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Chk2 (human, recombinant)
Artikelnummer: Cay43753-10
Checkpoint kinase 2 (Chk2) is a serine/threonine kinase and downstream effector of ataxia-telangiectasia mutated kinase (ATM) in the cellular DNA damage response. It is composed of an N-terminal serine-glutamine/threonine-glutamine cluster domain (SCD), a central forkhead-associated (FHA) domain, and a C-terminal...
| Schlagworte: | Cell Cycle Checkpoint Kinase 2, Checkpoint Kinase 2, CHK2 Checkpoint Homolog, Serine/threonine-protein Kinase Chk2 |
| Anwendung: | WB |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
ab 516,00 €
Anti-Recombinant Chk2, clone 5F3
Artikelnummer: E-AN300955L.100
In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for...
| Schlagworte: | Anti-CHEK2, Anti-Cds1 homolog, Anti-Checkpoint kinase 2, Anti-CHK2 checkpoint homolog, Anti-Serine/threonine-protein... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-phospho-Chk2 (Ser33/Ser35) / Checkpoint kinase 2,...
Artikelnummer: NSJ-FY12280
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-Chk2 (Ser33/Ser35) antibody recognizes checkpoint kinase 2 (Chk2) when phosphorylated at serine 33 and serine 35. Chk2 is a serine/threonine kinase that plays a pivotal role in DNA damage...
| Schlagworte: | Anti-phospho-CHEK2, Anti-phospho-Cds1 homolog, Anti-phospho-Checkpoint kinase 2, Anti-phospho-CHK2 checkpoint homolog,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-Phospho-Chk2 (Thr68) Monoclonal Recombinant Antibody
Artikelnummer: E-AN300151L.100
In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for...
| Schlagworte: | CDS1, hCds1, Hucds1, Cds1 homolog, Checkpoint kinase 2, CHK2 checkpoint homolog, Serine/threonine-protein kinase Chk2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 182,00 €
Anti-Phospho-Chk2 (Thr68)
Artikelnummer: E-AB-20843.20
Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18'...
| Schlagworte: | Anti-phospho-CDS1, Anti-phospho-hCds1, Anti-phospho-CHEK2, Anti-phospho-Hucds1, EC=2.7.11.1, Anti-phospho-Cds1 homolog,... |
| Anwendung: | WB, IHC (paraffin), IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-Chk2
Artikelnummer: ARG54652.50
Protein function: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation,...
| Schlagworte: | Anti-CDS1, Anti-CHEK2, Anti-hCds1, Anti-Hucds1, EC=2.7.11.1, Anti-Cds1 homolog, Anti-Checkpoint kinase 2, Anti-CHK2... |
| Anwendung: | ELISA, WB, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
625,00 €
Anti-Chk2
Artikelnummer: A300-618A
Protein function: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation,...
| Schlagworte: | Anti-CDS1, Anti-hCds1, Anti-CHEK2, Anti-Hucds1, EC=2.7.11.1, Anti-Cds1 homolog, Anti-Checkpoint kinase 2, Anti-CHK2... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-Chk2
Artikelnummer: A300-619A
Protein function: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation,...
| Schlagworte: | Anti-CDS1, Anti-hCds1, Anti-CHEK2, Anti-Hucds1, EC=2.7.11.1, Anti-Cds1 homolog, Anti-Checkpoint kinase 2, Anti-CHK2... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-Chk2
Artikelnummer: A300-620A
Protein function: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation,...
| Schlagworte: | Anti-CDS1, Anti-hCds1, Anti-CHEK2, Anti-Hucds1, EC=2.7.11.1, Anti-Cds1 homolog, Anti-Checkpoint kinase 2, Anti-CHK2... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-Chk2 (IHC)
Artikelnummer: IHC-00043
Protein function: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation,...
| Schlagworte: | Anti-CDS1, Anti-hCds1, Anti-CHEK2, Anti-Hucds1, EC=2.7.11.1, Anti-Cds1 homolog, Anti-Checkpoint kinase 2, Anti-CHK2... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
CHK2, active human recombinant protein
Artikelnummer: BPS-40040
Active human Checkpoint kinase 2 (GenBank Accession No. NM_007194), full length, with N-terminal HIS-tag. MW=91kDa. Expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | CDS1, hCds1, CHEK2, Hucds1, EC=2.7.11.1, Cds1 homolog, Checkpoint kinase 2, CHK2 checkpoint homolog,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 91 kD |
536,00 €
Anti-phospho-Chk2 (Thr68) (Checkpoint Kinase 2, Rad 53)
Artikelnummer: 600-401-280
Protein function: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation,...
| Schlagworte: | Anti-phospho-CDS1, Anti-phospho-CHEK2, Anti-phospho-hCds1, Anti-phospho-Hucds1, EC=2.7.11.1, Anti-phospho-Cds1 homolog,... |
| Anwendung: | ELISA, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
733,00 €