- Suchergebnis für O60341
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Zu "O60341" wurden 49 Artikel gefunden!
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Artikelnummer: A300-215A
Protein function: Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a...
Schlagworte: | Anti-AOF2, Anti-KDM1A, EC=1.-.-.-, Anti-BRAF35-HDAC complex protein BHC110, Anti-Lysine-specific histone demethylase 1A,... |
Anwendung: | WB, IP, IHC, ChIP-Seq |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: Cay700120-96
Lysine-specific demethylase 1 (LSD1) is a histone demethylase whose actions on specific lysine residues repress transcription of chromosomal DNA. LSD1 also inhibits the tumor suppressor activity of p53 by demethylating a specific lysine residue. Inhibitors of LSD1 are important tools used to elucidate mechanisms of...
Schlagworte: | Lysine-Specific Demethylase 1 |
Anwendung: | LSD1 inhibitor screening |
Spezies-Reaktivität: | human |
436,00 €
Artikelnummer: BPS-50109
The LSD1 Chemiluminescent Assay Kit is designed to directly measure activity of human lysine-specific demethylase (LSD1) for screening and profiling applications. LSD1 is a chromatin-modifying enzyme that specifically removes methyl groups from mono- and dimethylated Lys of histone H3. LSD1 is a critical component...
Schlagworte: | AOF2, BRAF35-HDAC complex protein BHC110, Lysine-specific histone demethylase 1A, Flavin-containing amine oxidase... |
Anwendung: | Enzyme kinetics, HTS |
1.021,00 €
Artikelnummer: A300-216A-T
Protein function: Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a...
Schlagworte: | Anti-AOF2, Anti-KDM1A, EC=1.-.-.-, Anti-BRAF35-HDAC complex protein BHC110, Anti-Lysine-specific histone demethylase 1A,... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: BPS-50097
Human LSD1 [also known as KDM1A (lysine (K)-specific demethylase 1A) or AOF2, amine oxidase (flavin containing) domain 2)] GenBank Accession No. NM_015013, a.a. 158-end, MW=77.9 kDa, expressed in E. coli expression system with N-terminal GST tag and PreScission Protease site. GST-tag was cleaved after affinity...
Schlagworte: | AOF2, BRAF35-HDAC complex protein BHC110, Lysine-specific histone demethylase 1A, Flavin-containing amine oxidase... |
Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 77.9 kD |
664,00 €
Artikelnummer: BPS-50100
Active human LSD1, AOF2, amine oxidase, flavin containing, domain 2, GenBank Accession No. NM_015013, amino acids 158-end with N-terminal GST tag, MW=103 kDa, expressed in E. coli expression system.
Schlagworte: | AOF2, BRAF35-HDAC complex protein BHC110, Lysine-specific histone demethylase 1A, Flavin-containing amine oxidase... |
Anwendung: | Enzyme kinetics |
MW: | 103 kD |
701,00 €
Artikelnummer: IHC-00122
Protein function: Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a...
Schlagworte: | Anti-AOF2, Anti-KDM1A, EC=1.-.-.-, Anti-BRAF35-HDAC complex protein BHC110, Anti-Lysine-specific histone demethylase 1A,... |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: ARG53984.100
Protein function: Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a...
Schlagworte: | Anti-AOF2, Anti-KDM1A, EC=1.-.-.-, Anti-BRAF35-HDAC complex protein BHC110, Anti-Lysine-specific histone demethylase 1A,... |
Anwendung: | WB, ICC, IF, IP |
Wirt: | Mouse |
Spezies-Reaktivität: | human, monkey |
624,00 €
Artikelnummer: BPS-25302
LSD1 (lysine specific demethylase 1, UniProt/Swiss Prot entry O60341) is a component of the histone demethylase complex that uses FAD as a prosthetic goup. LSD1 may have a dual effect on gene transcription. As it demethylates the mono and dimethylated Lys 4 of histone H3, which are associated with transcriptional...
Schlagworte: | Anti-AOF2, Anti-BRAF35-HDAC complex protein BHC110, Anti-Lysine-specific histone demethylase 1A, Anti-Flavin-containing... |
Anwendung: | ChIP/ChIP-seq, ELISA, WB, IF |
Spezies-Reaktivität: | human |
873,00 €
Artikelnummer: BPS-50108
The LSD1 Homogenous Assay Kit is designed to measure activity of lysine-specific demethylase (LSD1) for screening and profiling applications. LSD1 is a chromatin-modifying enzyme that specifically removes methyl groups from mono- and dimethylated Lys of histone H3. LSD1 is a critical component of transcriptional...
Schlagworte: | AOF2, BRAF35-HDAC complex protein BHC110, Lysine-specific histone demethylase 1A, Flavin-containing amine oxidase... |
Anwendung: | Enzyme kinetics, HTS |
1.568,00 €
Artikelnummer: Cay13486-1
LSD1, the first known lysine-specific histone demethylase, is an 886 amino acid nuclear protein belonging to flavin monoamine oxidase family. It contains a SWIRM domain, a FAD-binding motif and an amine oxidase domaine. This protein is ubiquitously expressed and is a component of several histone deacetylase...
Schlagworte: | KDM1 |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
413,00 €
Artikelnummer: Cay13554-1
LSD1 is a flavin-containing nuclear protein having a N-terminal SWIRM domain, a C-terminal FAD-binding motif, and an amine oxidase domain. It functions as a transcriptional corepressor and catalyzes the flavin-dependent demethylation of Lys4 of histone 3 resulting in the formation of methyl-free lysine and release...
Schlagworte: | Amine Oxidase (flavin containing) Domain 2 |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
432,00 €