Zu "K26171" wurden 27 Artikel gefunden!
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Anti-Sigma-2 Receptor / SR2 / MAC30 / TMEM97
Artikelnummer: NSJ-RQ7469
0.5mg/ml if reconstituted with 0.2ml sterile DI water. SR2/MAC30/TMEM97 is a conserved integral membrane protein that plays a role in controlling cellular cholesterol levels. Protein function: Intracellular sigma-2 receptor that binds histatin 1/HN1 (Hst 1) at the endoplasmic reticulun (ER) membrane, which is...
| Schlagworte: | Anti-Sigma2 receptor, Anti-Sigma-2 receptor, Anti-Transmembrane protein 97, Anti-Sigma intracellular receptor 2,... |
| Anwendung: | WB, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
790,00 €
WLB-89462
Artikelnummer: Cay39736-1
WLB-89462 is a ligand of sigma intracellular receptor 2 (sigma2 receptor). It selectively binds to the sigma2 receptor (Ki = 13 nM) over the sigma1 receptor (Ki = 1,777 nM). WLB-89462 (10 µM) prevents decreases in the number of dopaminergic neurons in an in vitro model of neurodegeneration using primary rat neurons...
| Schlagworte: | 2-[4-[2-ethyl-5-(3-methyl-5-isoxazolyl)-4-pyrimidinyl]-1-piperidinyl]-1-(4-morpholinyl)-ethanone |
| Anwendung: | Sigma2 receptor ligand |
| CAS | 2849471-75-4 |
| MW: | 399.5 D |
ab 40,00 €
CM699 (hydrochloride)
Artikelnummer: Cay43519-1
A dual sigma receptor antagonist (Kis = 0.0141 and 0.00231 µM for the sigma1 and sigma2 receptors, respectively) and DAT inhibitor (Ki = 0.311 µM), selective for the sigma1 and sigma2 receptors and DAT over SERT (Ki = 2.83 µM) but also binds to NET (Ki = 0.232 µM), inhibits dopamine uptake in rat striatal...
| Schlagworte: | 1,3-dihydro-1-methyl-3-[4-(spiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl)butyl]-2H-benzimidazol-2-one, monohydrochloride |
| Anwendung: | sigma receptor antagonist , DAT inhibitor |
| MW: | 427.97 D |
ab 90,00 €
NEU
Human, TMEM97 cDNA ORF Clone, N-Myc tag
Artikelnummer: SNB-HG11353-NM
Protein Function: Sigma-2 receptor which contributes to ameliorate dysfunctional cellular processes and slow degenerative progression by regulating cell functions including cholesterol biosynthesis/trafficking, membrane trafficking, autophagy, lipid membrane-bound protein trafficking, and receptor stabilization at...
| Schlagworte: | TMEM97, Transmembrane protein 97, Sigma intracellular receptor 2, Meningioma-associated protein 30 |
| Spezies-Reaktivität: | human |
214,00 €
NEU
Human, TMEM97 cDNA ORF Clone, N-His tag
Artikelnummer: SNB-HG11353-NH
Protein Function: Sigma-2 receptor which contributes to ameliorate dysfunctional cellular processes and slow degenerative progression by regulating cell functions including cholesterol biosynthesis/trafficking, membrane trafficking, autophagy, lipid membrane-bound protein trafficking, and receptor stabilization at...
| Schlagworte: | TMEM97, Transmembrane protein 97, Sigma intracellular receptor 2, Meningioma-associated protein 30 |
| Spezies-Reaktivität: | human |
214,00 €
NEU
Rat TMEM97 qPCR Primer Pair
Artikelnummer: SNB-RP301085
Protein Function: Sigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking, and stabilization of receptors at the cell surface, thereby contributing to the...
| Schlagworte: | S2r, Tmem97, Transmembrane protein 97, Sigma intracellular receptor 2 |
| Anwendung: | qPCR |
| Spezies-Reaktivität: | rat |
92,00 €
NEU
Rat, TMEM97 cDNA ORF Clone, C-DYKDDDDK (Flag(R)) tag
Artikelnummer: SNB-RG81128-CF
Protein Function: Sigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking, and stabilization of receptors at the cell surface, thereby contributing to the...
| Schlagworte: | S2r, Tmem97, Transmembrane protein 97, Sigma intracellular receptor 2 |
| Spezies-Reaktivität: | rat |
214,00 €
NEU
Rat, TMEM97 cDNA ORF Clone, C-Myc tag
Artikelnummer: SNB-RG81128-CM
Protein Function: Sigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking, and stabilization of receptors at the cell surface, thereby contributing to the...
| Schlagworte: | S2r, Tmem97, Transmembrane protein 97, Sigma intracellular receptor 2 |
| Spezies-Reaktivität: | rat |
214,00 €
NEU
Rat, TMEM97 cDNA ORF Clone, C-GFPSpark(R) tag
Artikelnummer: SNB-RG81128-ACG
Protein Function: Sigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking, and stabilization of receptors at the cell surface, thereby contributing to the...
| Schlagworte: | S2r, Tmem97, Transmembrane protein 97, Sigma intracellular receptor 2 |
| Spezies-Reaktivität: | rat |
245,00 €
NEU
Human TMEM97 qPCR Primer Pair
Artikelnummer: SNB-HP101238
Protein Function: Sigma-2 receptor which contributes to ameliorate dysfunctional cellular processes and slow degenerative progression by regulating cell functions including cholesterol biosynthesis/trafficking, membrane trafficking, autophagy, lipid membrane-bound protein trafficking, and receptor stabilization at...
| Schlagworte: | TMEM97, Transmembrane protein 97, Sigma intracellular receptor 2, Meningioma-associated protein 30 |
| Anwendung: | qPCR |
| Spezies-Reaktivität: | human |
92,00 €
NEU
Rat, TMEM97 cDNA ORF Clone, untagged
Artikelnummer: SNB-RG81128-UT
Protein Function: Sigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking, and stabilization of receptors at the cell surface, thereby contributing to the...
| Schlagworte: | S2r, Tmem97, Transmembrane protein 97, Sigma intracellular receptor 2 |
| Spezies-Reaktivität: | rat |
214,00 €
NEU
Rat, TMEM97 cDNA ORF Clone, C-His tag
Artikelnummer: SNB-RG81128-CH
Protein Function: Sigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking, and stabilization of receptors at the cell surface, thereby contributing to the...
| Schlagworte: | S2r, Tmem97, Transmembrane protein 97, Sigma intracellular receptor 2 |
| Spezies-Reaktivität: | rat |
214,00 €