Zu "K25306" wurden 4 Artikel gefunden!
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PF-3450074
Artikelnummer: Cay36107-5
PF-3450074 (PF74) is an inhibitor of HIV-1 capsid protein. It reduces viral infectivity in HeLa cells infected with wild-type HIV-1 but not P38A, E45A, Q63A/Q67A, or Q219A capsid protein mutant HIV-1, simian immunodeficiency virus, or murine leukemia virus when used at a concentration of 10 µM. PF74 (0.62-10 µM)...
| Schlagworte: | PF74, 2-methyl-N-[(1S)-2-(methylphenylamino)-2-oxo-1-(phenylmethyl)ethyl]-1H-indole-3-acetamide |
| Anwendung: | HIV-1 capsid protein inhibitor |
| CAS | 1352879-65-2 |
| MW: | 425.5 D |
ab 45,00 €
CA inhibitor 1
Artikelnummer: TGM-T10658-100mg
Description: CA inhibitor 1 (GS-6207 analog) is a potent inhibitor of the HIV capsid. Target: HIV Protease. Smiles: [H][C@]12C[C@@]1([H])C(F)(F)c1c2c(nn1CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1nc(ccc1-c1ccc(Cl)c2c(NS(=O)(=O)C3CC3)nn(CC(F)F)c12)C#CC(C)(C)S(C)(=O)=O)C(F)F. References: Michael Graupe, et al. Therapeutic...
| Schlagworte: | GS-6207 analog |
| Anwendung: | CA inhibitor |
| CAS | 2189684-45-3 |
| MW: | 958.34 D |
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NEU
PF-3450074
Artikelnummer: TGM-T16500-100mg
Description: PF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nucleoporin 153), and blocks the uncoating, assembly, and the reverse transcription...
| Schlagworte: | PF-74 |
| Anwendung: | HIV-1 capsid protein inhibitor |
| CAS | 1352879-65-2 |
| MW: | 425.52 D |
ab 29,00 €
Lenacapavir
Artikelnummer: Cay41830-10
An inhibitor of HIV capsid protein-protein interactions, inhibits viral replication in HIV-1-infected primary human CD4+ T cells and macrophages (mean IC50s = 32 and 56 pM, respectively), two HIV-2 clinical isolates (mean IC50 = 885 pM), and 23 HIV-1 clinical isolates (mean IC50 = 50 pM), prevents stHIV-A19...
| Schlagworte: | GS-6207, GS-714207, GS-CA2,... |
| Anwendung: | HIV capsid protein-protein interaction inhibitor |
| CAS | 2189684-44-2 |
| MW: | 968.28 D |
ab 269,00 €
