Zu "K24669" wurden 69 Artikel gefunden!
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Calyculin A
Artikelnummer: Cay19246-10
Calyculin A is a natural, cell-permeable inhibitor of the serine-threonine protein phosphatases (PP) PP1 and PP2A (IC50s = 0.3-0.7 and 0.5-1 nM, respectively). It is without significant effect against PP2B, PP2C, and PP4. Through its effects on PP1 and PP2A, calyculin A has been shown to either promote or inhibit...
| Schlagworte: | (-)-Calyculin A,... |
| Anwendung: | Cell-permeable PP1 / PP2A inhibitor |
| CAS | 101932-71-2 |
| MW: | 1009,2 D |
ab 409,00 €
PAD4 (human, recombinant)
Artikelnummer: Cay10500-100
Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...
| Schlagworte: | PAD4, PADI4, HL-60 PAD, HL-60 PAD, Peptidylarginine deiminase IV, Peptidylarginine deiminase IV, Protein-arginine... |
| Anwendung: | Enzyme activity |
| MW: | 78.8 kD |
ab 634,00 €
PADI4, His, Human
Artikelnummer: GSC-Z05729-100
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has...
| Schlagworte: | PADI4, HL-60 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type-4, Protein-arginine deiminase type IV |
| Ursprungsart: | human |
| MW: | 76.6 kD |
ab 887,00 €
PAD4 (human, recombinant) - Biotinylated
Artikelnummer: Cay43452-100
Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...
| Schlagworte: | PADI4, PADI5, PDI5, Peptidylarginine Deiminase 4, Protein Arginine Deiminase Type 4, Protein Arginine Deiminase Type IV |
| Anwendung: | Active enzyme |
| Ursprungsart: | human |
634,00 €
Citrullinated BSA
Artikelnummer: Cay43743-200
Citrulline is a non-proteinogenic amino acid that is produced by deimination of arginine through the post-translational modification citrullination. Citrullination is catalyzed by protein arginine deiminases (PADs) that convert positively charged arginine to electrically neutral citrulline, decreasing the...
| Schlagworte: | Citrulline Bovine Serum Albumin, Citrulline-modified Bovine Serum Albumin |
| Anwendung: | PADI4 citrullinated |
440,00 €
![PADI4[Biotin], His, Human](https://www.biomol.com/media/image/0a/8d/2d/GSC-Z04580-100_200x200.png "PADI4[Biotin], His, Human")
PADI4[Biotin], His, Human
Artikelnummer: GSC-Z04580-100
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has...
| Schlagworte: | PADI4, HL-60 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type-4, Protein-arginine deiminase type IV |
| Ursprungsart: | human |
| MW: | 76.6 kD |
ab 1.129,00 €
PAD4 (human, recombinant, mammalian expressed)
Artikelnummer: Cay32834-50
Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...
| Schlagworte: | PAD4, PADI4, HL-60 PAD, HL-60 PAD, Peptidylarginine deiminase IV, Peptidylarginine deiminase IV, Protein-arginine... |
| Anwendung: | Enzyme assays |
| Ursprungsart: | human |
748,00 €
PAD4 Autoantibody High Sensitivity ELISA Kit
Artikelnummer: Cay502865-96
Cayman's PAD4 Autoantibody High-Sensitivity ELISA Kit is an immunometric assay that can be used to measure IgG, IgM, or IgA isotypes of PAD4 autoantibodies in human plasma and serum without prior sample purification., , The levels of PAD4 autoantibodies in samples can be estimated using a standard curve. Please...
| Schlagworte: | PAD4 Autoantibody EIA Kit, PADI4, PADI5, PDI5, Peptidylarginine Deiminase 4, Protein Arginine Deiminase 4 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
735,00 €
BB-Cl-Amidine
Artikelnummer: Cay17079-1
BB-Cl-amidine is a pan inhibitor of peptidyl arginine deiminases (PADs) and a proteolysis-resistant derivative of Cl-amidine (Cay-10599). It irreversibly inhibits PAD1-4 (kinact/KI = 16,100, 4,100, 6,800, and 13,300 M-1min-1, respectively). BB-Cl-amidine (20 and 200 µM) inhibits the formation of neutrophil...
| Schlagworte: | N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-[1,1'-biphenyl]-4-carboxamide |
| Anwendung: | PADI4 inhibitor |
| CAS | 1802637-39-3 |
| MW: | 460 D |
ab 102,00 €
PAD4 Inhibitor Screening Assay Kit (Ammonia)
Artikelnummer: Cay700560-96
Cayman's PAD4 Inhibitor Screening Assay Kit (Ammonia) provides a convenient method for screening human PAD4 inhibitors. PAD4 deiminates N-alpha-benzoyl-L-arginine ethyl ester (BAEE), a non-natural substrate with similar kinetic properties to the natural substrates, producing ammonia.3 Ammonia reacts with a detector...
| Schlagworte: | PADI4, PADI5, PDI5, Peptidylarginine Deiminase 4, Protein Arginine Deiminase 4 |
| Anwendung: | HTS |
| Spezies-Reaktivität: | human |
732,00 €
JBI-589
Artikelnummer: Cay42126-1
Solulibility: Acetonitrile: Slightly Soluble: 0.1-1 mg/ml: DMSO: Slightly Soluble: 0.1-1 mg/ml.
| Schlagworte: | [(3R)-3-amino-1-piperidinyl][2-[1-[(4-fluorophenyl)methyl]-1H-indol-2-yl]-3-methylimidazo[1,2-a]pyridin-7-yl]-methanone |
| Anwendung: | PADI4 inhibitor |
| CAS | 2308504-22-3 |
| MW: | 481.56 D |
ab 260,00 €
PAD4 (human) ELISA Kit
Artikelnummer: Cay501460-96
Cayman's PAD4 (human) ELISA Kit is a sandwich assay that can be used to measure PAD4 in tissue culture medium, cell lysates, plasma, and serum. The standard curve spans the range of 0.16-10 ng/ml.Synonyms: PADI4, PADI5, PDI5, Peptidylarginine Deiminase 4 (human) EIA Kit, Peptidyl Arginine Deiminase 4. Assay Range:...
| Schlagworte: | PADI4, PADI5, PDI5, Peptidyl Arginine Deiminase 4, Peptidylarginine Deiminase 4 (human) EIA Kit |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
844,00 €