Zu "K24669" wurden 76 Artikel gefunden!
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PAD4 (L117M mutant, human, recombinant)
Artikelnummer: Cay44266-100
Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...
| Schlagworte: | PADI4 rs1748033, PADI5 (L117M), Protein Arginine Deiminase Type 4 (L117M), Protein Arginine Deiminase Type IV (L117M) |
| Anwendung: | WB, active enzyme |
| Ursprungsart: | human |
ab 223,00 €
Calyculin A
Artikelnummer: Cay19246-10
Calyculin A is a natural, cell-permeable inhibitor of the serine-threonine protein phosphatases (PP) PP1 and PP2A (IC50s = 0.3-0.7 and 0.5-1 nM, respectively). It is without significant effect against PP2B, PP2C, and PP4. Through its effects on PP1 and PP2A, calyculin A has been shown to either promote or inhibit...
| Schlagworte: | (-)-Calyculin A,... |
| Anwendung: | Cell-permeable PP1 / PP2A inhibitor |
| CAS | 101932-71-2 |
| MW: | 1009,2 D |
ab 421,00 €
PAD4 (human, recombinant)
Artikelnummer: Cay10500-100
Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...
| Schlagworte: | PAD4, PADI4, HL-60 PAD, HL-60 PAD, Peptidylarginine deiminase IV, Peptidylarginine deiminase IV, Protein-arginine... |
| Anwendung: | Enzyme activity |
| MW: | 78.8 kD |
ab 654,00 €
PAD4 (human, recombinant) - Biotinylated
Artikelnummer: Cay43452-100
Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...
| Schlagworte: | PADI4, PADI5, PDI5, Peptidylarginine Deiminase 4, Protein Arginine Deiminase Type 4, Protein Arginine Deiminase Type IV |
| Anwendung: | Active enzyme |
| Ursprungsart: | human |
654,00 €
PAD4 (human, recombinant, mammalian expressed)
Artikelnummer: Cay32834-50
Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...
| Schlagworte: | PAD4, PADI4, HL-60 PAD, HL-60 PAD, Peptidylarginine deiminase IV, Peptidylarginine deiminase IV, Protein-arginine... |
| Anwendung: | Enzyme assays |
| Ursprungsart: | human |
771,00 €
Citrullinated BSA
Artikelnummer: Cay43743-200
Citrulline is a non-proteinogenic amino acid that is produced by deimination of arginine through the post-translational modification citrullination. Citrullination is catalyzed by protein arginine deiminases (PADs) that convert positively charged arginine to electrically neutral citrulline, decreasing the...
| Schlagworte: | Citrulline Bovine Serum Albumin, Citrulline-modified Bovine Serum Albumin |
| Anwendung: | PADI4 citrullinated |
454,00 €
BB-Cl-Amidine
Artikelnummer: Cay17079-1
BB-Cl-amidine is a pan inhibitor of peptidyl arginine deiminases (PADs) and a proteolysis-resistant derivative of Cl-amidine (Cay-10599). It irreversibly inhibits PAD1-4 (kinact/KI = 16,100, 4,100, 6,800, and 13,300 M-1min-1, respectively). BB-Cl-amidine (20 and 200 µM) inhibits the formation of neutrophil...
| Schlagworte: | N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-[1,1'-biphenyl]-4-carboxamide |
| Anwendung: | PADI4 inhibitor |
| CAS | 1802637-39-3 |
| MW: | 460 D |
ab 105,00 €
PAD4 Inhibitor Screening Assay Kit (Ammonia)
Artikelnummer: Cay700560-96
Cayman's PAD4 Inhibitor Screening Assay Kit (Ammonia) provides a convenient method for screening human PAD4 inhibitors. PAD4 deiminates N-alpha-benzoyl-L-arginine ethyl ester (BAEE), a non-natural substrate with similar kinetic properties to the natural substrates, producing ammonia.3 Ammonia reacts with a detector...
| Schlagworte: | PADI4, PADI5, PDI5, Peptidylarginine Deiminase 4, Protein Arginine Deiminase 4 |
| Anwendung: | HTS |
| Spezies-Reaktivität: | human |
755,00 €
PAD4 Autoantibody High Sensitivity ELISA Kit
Artikelnummer: Cay502865-96
Cayman's PAD4 Autoantibody High-Sensitivity ELISA Kit is an immunometric assay that can be used to measure IgG, IgM, or IgA isotypes of PAD4 autoantibodies in human plasma and serum without prior sample purification., , The levels of PAD4 autoantibodies in samples can be estimated using a standard curve. Please...
| Schlagworte: | PAD4 Autoantibody EIA Kit, PADI4, PADI5, PDI5, Peptidylarginine Deiminase 4, Protein Arginine Deiminase 4 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
757,00 €
PAD4 (mouse, recombinant)
Artikelnummer: Cay28910-100
Protein arginine deiminase 4 (PAD4) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is expressed in neutrophils, as well as a variety of tissues, including the brain,...
| Schlagworte: | Pad4, Padi4, Peptidylarginine deiminase IV, Peptidylarginine deiminase IV, Protein-arginine deiminase type-4,... |
| Anwendung: | Enzyme assays |
| Exprimiert in: | Insect cells |
| MW: | 76.08 kD |
734,00 €
BMS-P5
Artikelnummer: Cay33581-10
BMS-P5 is an inhibitor of protein arginine deiminase 4 (PAD4, IC50 = 0.098 µM). It is selective for PAD4 over PAD1, -2, and -3 (IC50s = >10 µM for all). BMS-P5 (1 µM) inhibits citrullination of histone H3 and neutrophil extracellular trap (NET) formation induced by RPMI-8226- or MM.1S-conditioned medium in isolated...
| Schlagworte: | [(2S,5R)-5-amino-2-methyl-1-piperidinyl][2-[1-(cyclopropylmethyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-7-methoxy-1-methyl-1H-met... |
| Anwendung: | PADI4 inhibitor |
| CAS | 1550371-22-6 |
| MW: | 472.6 D |
ab 51,00 €
Anti-PAD4
Artikelnummer: NSJ-R31153
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Peptidylarginine Deiminase, Type IV is a human protein which in humans is encoded by the PADI4 gene. Peptidylarginine deiminases make up a family of posttranslational modification enzymes that convert arginine residues to citrulline residues in the presence of...
| Schlagworte: | Anti-PAD4, Anti-PADI4, Anti-HL-60 PAD, EC=3.5.3.15, Anti-Peptidylarginine deiminase IV, Anti-Protein-arginine deiminase... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €