Zu "K23967" wurden 22 Artikel gefunden!
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Anti-phospho-KCC2 (Thr1007)
Artikelnummer: Cay29292-100
The neuronal-specific potassium chloride cotransporter 2 (KCC2) is a member of the SLC12 family of transporters and is encoded by SLC12A5 in humans. KCC2 is expressed in mature neurons throughout the CNS and localizes to the soma and dendrite plasma membrane where it mediates chloride ion efflux, maintaining the...
| Schlagworte: | Electroneutral Potassium Chloride Cotransporter 2, Neuronal Potassium Chloride Cotransporter |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
649,00 €
Anti-phospho-Potassium Chloride Cotransporter (KCC2)...
Artikelnummer: 612-401-E15
Anti-Potassium Chloride Cotransporter (KCC2) pS940 antibody is directed against phosphorylated rat KCC2 protein. THe antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling of the KCC2 protein band is blocked by the phospho-peptide used as antigen but not by the...
| Schlagworte: | Anti-phospho-Kcc2, Anti-phospho-rKCC2, Anti-phospho-Slc12a5, Anti-phospho-K-Cl cotransporter 2, Anti-phospho-Neuronal K-Cl... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
684,00 €
CLP 257
Artikelnummer: Cay30948-5
CLP 257 is a K+/Cl- cotransporter 2 (KCC2) activator. It induces chloride transport in NG108-cl cells that endogenously express low levels of KCC2 (EC50 = 616 nM). It is selective for KCC2 over GABAA receptors at 50 µM. CLP 257 (25 µM) increases the rate of chloride accumulation in spinal slices isolated from a rat...
| Schlagworte: | (5Z)-5-[(4-fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1(2H)-pyridazinyl)-4(5H)-thiazolone |
| Anwendung: | KCC2 cotransporter activator |
| CAS | 1181081-71-9 |
| MW: | 307.3 D |
ab 43,00 €
Anti-KCC2, clone S1-12
Artikelnummer: ARG22238.50
Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors,...
| Schlagworte: | Anti-Kcc2, Anti-rKCC2, Anti-Slc12a5, Anti-K-Cl cotransporter 2, Anti-Neuronal K-Cl cotransporter, Anti-Solute carrier... |
| Anwendung: | WB, IHC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
520,00 €
Anti-Potassium Chloride Cotransporter / KCC2
Artikelnummer: ARG56210.100
Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors,...
| Schlagworte: | Anti-KCC2, Anti-hKCC2, Anti-SLC12A5, Anti-K-Cl cotransporter 2, Anti-Neuronal K-Cl cotransporter, Anti-Solute carrier... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
584,00 €
Anti-phospho-KCC2 / Potassium Chloride Cotransporter...
Artikelnummer: ARG40886.50
Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors,...
| Schlagworte: | Anti-phospho-Kcc2, Anti-phospho-mKCC2, Anti-phospho-Slc12a5, Anti-phospho-K-Cl cotransporter 2, Anti-phospho-Neuronal K-Cl... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, bovine, primates, swine, sheep |
592,00 €
Anti-SLC12A5
Artikelnummer: E-AB-18162.120
K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients...
| Schlagworte: | Anti-KCC2, Anti-hKCC2, Anti-SLC12A5, Anti-K-Cl cotransporter 2, Anti-Neuronal K-Cl cotransporter, Anti-Solute carrier... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-SLC12A5
Artikelnummer: E-AB-52074.120
K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients...
| Schlagworte: | Anti-KCC2, Anti-hKCC2, Anti-SLC12A5, Anti-K-Cl cotransporter 2, Anti-Neuronal K-Cl cotransporter, Anti-Solute carrier... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-KCC2 (Phospho-Ser940)
Artikelnummer: Cay29291-100
The neuronal-specific potassium chloride cotransporter 2 (KCC2) is a member of the SLC12 family of transporters and is encoded by SLC12A5 in humans. KCC2 is expressed in mature neurons throughout the CNS and localizes to the soma and dendrite plasma membrane where it mediates chloride ion efflux, maintaining the...
| Schlagworte: | Electroneutral Potassium Chloride Cotransporter 2, Neuronal Potassium Chloride Cotransporter |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
530,00 €
CLP 290
Artikelnummer: Cay31448-1
CLP 290 is a carbamate prodrug form of the K+/Cl- cotransporter 2 (KCC2) activator CLP 257 (Cay-30948). It increases the mechanical paw withdrawal threshold in a rat model of peripheral nerve injury and reverses morphine-induced hyperalgesia in rats when administered at a dose of 100 mg/kg. CLP 290 (35 mg/kg) also...
| Schlagworte: | 1-pyrrolidinecarboxylic acid, 5-fluoro-2-[(Z)-[4-oxo-2-(tetrahydro-1(2H)-pyridazinyl)-5(4H)-thiazolylidene]methyl]phenyl... |
| Anwendung: | KCC2 activator prodrug |
| CAS | 1181083-81-7 |
| MW: | 404.5 D |
ab 44,00 €
Anti-SLC12A5
Artikelnummer: G-CAB15486.100
WB 1:200 - 1:2000. Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to...
| Schlagworte: | Anti-KCC2, Anti-hKCC2, Anti-SLC12A5, Anti-K-Cl cotransporter 2, Anti-Neuronal K-Cl cotransporter, Anti-Solute carrier... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €
Anti-SLC12A5
Artikelnummer: G-CAB15487.100
WB 1:200 - 1:2000. Protein function: Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to...
| Schlagworte: | Anti-KCC2, Anti-hKCC2, Anti-SLC12A5, Anti-K-Cl cotransporter 2, Anti-Neuronal K-Cl cotransporter, Anti-Solute carrier... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 352,00 €