Zu "K22531" wurden 28 Artikel gefunden!
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BAY-850
Artikelnummer: Cay23422-1
BAY-850 is an inhibitor of the ATPase family AAA domain-containing protein 2 (ATAD2, IC50 = 22 nM in a time-resolved FRET assay using a tetra-acetylated histone H4 peptide). It is selective for ATAD2 over a panel of 32 bromodomain family proteins, including ATAD2B, a panel of 354 kinases, and a panel of 25 G...
| Schlagworte: | N-[(1R)-2-[(cis-4-aminocyclohexyl)amino]-1-[(4-cyanophenyl)methyl]ethyl]-2-chloro-4-methoxy-5-[5-[[[(1R)-1-(4-methylphenyl... |
| Anwendung: | ATAD2 inhibitor |
| CAS | 2099142-76-2 |
| MW: | 654.2 D |
ab 67,00 €
ATAD2A (981-1108), human, recombinant, N-terminal His tag
Artikelnummer: BPS-31109
Human Bromodomain ATAD2A, amino acids 981 ? 1108 (GenBank Accession No. NM_014109) with N-terminal HIS-tag, MW = 16.2 kDa, expressed in an E. coli expression system.
| Schlagworte: | L16, ANCCA, ATAD2, EC=3.6.1.-, ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated... |
| Anwendung: | BRD binding assays, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 16.2 kD |
461,00 €
ATAD2B (953-1080), human recombinant protein
Artikelnummer: BPS-31117
Human bromodomain ATPase family, AAA domain containing 2B (variant 1), amino-acids 951 - 1080, (GenBank Accession No. NM_017552) with N-terminal HIS-tag, MW = 15.9 kDa, expressed in an E. coli expression system.
| Schlagworte: | ATAD2B, KIAA1240, ATPase family AAA domain-containing protein 2B, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 15.9 kD |
461,00 €
ATAD2A (981-1108), human, recombinant, N-terminal GST tag
Artikelnummer: BPS-31121
Human Bromodomain ATAD2A, amino-acids 981 ? 1108 (GenBank Accession No. NM_014109) with N-terminal GST-tag, MW = 42 kDa, expressed in an E. coli expression system.
| Schlagworte: | L16, ANCCA, ATAD2, EC=3.6.1.-, ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated... |
| Anwendung: | BRD binding assays, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 42 kD |
461,00 €
ATAD2B (953-1080), GST-tag, human recombinant protein
Artikelnummer: BPS-31125
Human bromodomain ATPase family, AAA domain containing 2B (variant 1), amino-acids 953 - 1080, (GenBank Accession No. NM_017552) with N-terminal GST-tag, MW = 42 kDa, expressed in an E. coli expression system.
| Schlagworte: | ATAD2B, KIAA1240, ATPase family AAA domain-containing protein 2B, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 42 kD |
461,00 €
ATAD2A Inhibitor Screening Assay Kit
Artikelnummer: BPS-32601
The ATAD2A Inhibitor Screening Assay Kit is designed to measure the inhibition of ATAD2A bromodomain binding to its substrate. The kit comes in a convenient AlphaLISA(R) format, with biotinylated histone peptide substrate, assay buffer, detection buffer and purified ATAD2A for 384 assays.
| Schlagworte: | KIAA1240, AAA domain containing 2B (variant 1), |
| Anwendung: | ATAD2A inhibitor screening |
1.563,00 €
ATAD2B Inhibitor Screening Assay Kit
Artikelnummer: BPS-32605
The ATAD2B Inhibitor Screening Assay Kit is designed to measure the inhibition of ATAD2B binding to its substrate. The kit comes in a convenient AlphaLISA format, with enough biotinylated histone peptide substrate, assay buffer, detection buffer and purified GST-tagged ATAD2B bromodomain to perform a total of 384...
| Schlagworte: | ATAD2B, KIAA1240, ATPase family AAA domain-containing protein 2B |
| Anwendung: | Bromodomain binding assays, inhibitor screening, selectivity profiling |
1.563,00 €
ATAD2A TR-FRET Assay Kit
Artikelnummer: BPS-32618
The ATAD2A TR-FRET Assay Kit is designed to measure the inhibition of ATAD2A binding to its substrate in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications.
| Schlagworte: | KIAA1240, AAA domain containing 2B (variant 1), |
| Anwendung: | Screening small molecular inhibitors for drug discovery, HTS applications |
| Spezies-Reaktivität: | human |
804,00 €
ATAD2B TR-FRET Assay Kit
Artikelnummer: BPS-32620
The ATAD2B TR-FRET Assay Kit is designed to measure the inhibition of ATAD2B binding to its substrate in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward...
| Schlagworte: | KIAA1240, AAA domain containing 2B (variant 1), |
| Anwendung: | Screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
804,00 €
ATAD2 bromodomain (human recombinant)
Artikelnummer: Cay14490-100
The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in linking protein complexes to acetylated nucleosomes, thereby controlling chromatin...
| Schlagworte: | L16, ATAD2, ANCCA, ANCCA, ATPase family AAA domain-containing protein 2, ATPase family AAA domain-containing protein 2,... |
| Anwendung: | Estrogen and androgen receptor coactivator |
| Exprimiert in: | E.coli |
| MW: | 43,1 kD |
491,00 €
Anti-ATAD2, clone CL0182
Artikelnummer: ATA-AMAb90541.100
Protein function: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone...
| Schlagworte: | Anti-L16, Anti-ATAD2, Anti-ANCCA, EC=3.6.1.-, Anti-ATPase family AAA domain-containing protein 2, Anti-AAA nuclear... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 320,00 €
Anti-ATAD2
Artikelnummer: ATA-HPA029424.100
Protein function: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone...
| Schlagworte: | Anti-L16, Anti-ATAD2, Anti-ANCCA, EC=3.6.1.-, Anti-ATPase family AAA domain-containing protein 2, Anti-AAA nuclear... |
| Anwendung: | IHC, WB, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €