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Zu "K22182" wurden 86 Artikel gefunden!
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Artikelnummer: NSJ-FY13051
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. TXNRD1 antibody detects Thioredoxin reductase 1, a selenocysteine-containing enzyme that maintains cellular redox balance by catalyzing the NADPH-dependent reduction of thioredoxin. The UniProt recommended name is Thioredoxin reductase 1...
| Schlagworte: | Anti-TXNRD1, Anti-Peroxidase TXNRD1, Anti-Thioredoxin reductase TR1, Anti-Thioredoxin reductase 1, cytoplasmic,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Artikelnummer: Cay15343-1
An inhibitor of TrxR (mean IC50 = 6.5 µM for the rat enzyme), inhibits cell growth in the NCI-60 panel of cancer cell lines (mean GI50 = 0.23 µM), inhibits IL-1beta-induced NF-kappaB DNA binding in A549 cells at 30 µM
| Schlagworte: | AW-464, 4-(2-benzothiazolyl)-4-hydroxy-2,5-cyclohexadien-1-one |
| Anwendung: | TrxR (thioredoxin reductase) inhibitor |
| CAS | 485842-97-5 |
| MW: | 243.3 D |
ab 88,00 €
Artikelnummer: E-AN200069P.100
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each...
| Schlagworte: | TR, GRIM12, GRIM-12, Peroxidase TXNRD1, Thioredoxin reductase TR1, KM-102-derived reductase-like factor, Thioredoxin... |
| Anwendung: | FCM, ICC/IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
389,00 €
Artikelnummer: Cay36636-1
LCS3 is an inhibitor of glutathione reductase (GR) and thioredoxin reductase (TrxR, IC50s = 3.3 and 3.8 µM, respectively). It decreases the glutathione (GSH) to oxidized GSH (GSSG) ratio in NCI H1650 and H23 lung adenocarcinoma cells in a concentration-dependent manner. LCS3 (3 µM) induces apoptosis in NCI H1650 and...
| Schlagworte: | N-(4-chlorophenyl)-5-nitro-2-furancarboxamide |
| Anwendung: | GR / TrxR inhibitor |
| CAS | 109844-92-0 |
| MW: | 266.6 D |
ab 50,00 €
Artikelnummer: Cay39624-200
Thioredoxin reductase 1 (TrxR1) is an oxidoreductase encoded by the TXNRD1 gene in humans and a member of the antioxidant thioredoxin system, which is involved in the maintenance of cellular thiol redox homeostasis. It exists as a homodimer and contains a dimer interface domain, FAD- and NADPH-binding domains, an...
| Schlagworte: | NADPH-dependent Thioredoxin Reductase, TrxR1, TR, TXNRD1, GRIM12, GRIM-12, EC=1.8.1.9, Thioredoxin reductase TR1,... |
| Anwendung: | WB, SDS-PAGE |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | ~55 kD |
1.110,00 €
Artikelnummer: ARG54100.100
Protein function: Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling. [The UniProt Consortium]
| Schlagworte: | Anti-SelZ, Anti-TXNRD2, Anti-TR-beta, Anti-KIAA1652, EC=1.8.1.9, Anti-Selenoprotein Z, Anti-Thioredoxin reductase TR3,... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Artikelnummer: ARG57177.50
Protein function: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the...
| Schlagworte: | Anti-TR, Anti-GRIM12, Anti-TXNRD1, Anti-GRIM-12, EC=1.8.1.9, Anti-Thioredoxin reductase TR1, Anti-KM-102-derived... |
| Anwendung: | WB, FC, ICC, IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
518,00 €
Artikelnummer: ARG63486.100
Protein function: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the...
| Schlagworte: | Anti-TR, Anti-GRIM12, Anti-TXNRD1, Anti-GRIM-12, EC=1.8.1.9, Anti-Thioredoxin reductase TR1, Anti-Thioredoxin reductase 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Artikelnummer: A304-791A
Protein function: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the...
| Schlagworte: | Anti-TR, Anti-GRIM12, Anti-TXNRD1, Anti-GRIM-12, EC=1.8.1.9, Anti-Thioredoxin reductase TR1, Anti-Thioredoxin reductase 1,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Artikelnummer: G-MOFI01171.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Artikelnummer: NSJ-R31003
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Thioredoxin reductase 2 is also known as TRXR2, TR3, SELZ, or TR-BETA. Thioredoxin reductases, are selenocysteine (sec)-containing flavoenzymes that maintain thioredoxins, small proteins that catalyze redox reactions, in the reduced state using the reducing...
| Schlagworte: | Anti-SelZ, Anti-TR-beta, Anti-KIAA1652, Anti-Selenoprotein Z, Anti-Thioredoxin reductase TR3, Anti-Thioredoxin reductase... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
790,00 €
Artikelnummer: NSJ-R36197-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Thioredoxin Reductase 1 Protein function: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation...
| Schlagworte: | Anti-TR, Anti-GRIM12, Anti-TXNRD1, Anti-GRIM-12, EC=1.8.1.9, Anti-Thioredoxin reductase TR1, Anti-Thioredoxin reductase 1,... |
| Anwendung: | WB, ELISA (peptide), IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €