Zu "K22128" wurden 20 Artikel gefunden!
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Yoda 1
Artikelnummer: TGM-T7506-100mg
Description: Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1 (EC50=17.1/26.6 µM). Yoda 1 is also an inhibitor of glycine transporter protein 2 (GlyT2). Target: Piezo Channel. Smiles: Clc1cccc(Cl)c1CSc1nnc(s1)-c1cnccn1. References: Ruhma S , Jie X , Dubin A E , et al. Chemical...
| Anwendung: | Piezo1 agonist |
| CAS | 448947-81-7 |
| MW: | 355.27 D |
ab 40,00 €
PIEZO1 Protein, Human, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-01863-100ug
Description: PIEZO1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.6 kDa and the accession number is Q92508.
| Schlagworte: | Protein FAM38A, Piezo-type mechanosensitive ion channel component 1, Membrane protein induced by beta-amyloid treatment,... |
| MW: | 33.6 kD |
ab 281,00 €
Yoda1
Artikelnummer: Cay21904-1
Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 µM for murine and human Piezo1-transfected HEK293T cells, respectively). It is selective for Piezo1 as it elicits Ca2+ flux in Piezo1- but not Piezo2-transfected HEK293T cells. Yoda1 slows the inactivation phase of murine Piezo1 transient currents and...
| Schlagworte: | 2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-pyrazine |
| Anwendung: | Piezo1 agonist |
| CAS | 448947-81-7 |
| MW: | 355.3 D |
ab 45,00 €
Piezo-type mechanosensitive ion channel component 2...
Artikelnummer: CSB-EP887983HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2427-2661aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: KSVAGVINQP LDVSVTITLG GYQPIFTMSA QQSQLKVMDQ QSFNKFIQAF SRDTGAMQFL ENYEKEDITV AELEGNSNSL WTISPPSKQK MIHELLDPNS SFSVVFSWSI QRNLSLGAKS EIATDKLSFP...
| Schlagworte: | PIEZO2, C18orf30, Protein FAM38B, Piezo-type mechanosensitive ion channel component 2, Recombinant Human Piezo-type... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 33.3 kD |
ab 292,00 €
Piezo-type mechanosensitive ion channel component 1...
Artikelnummer: CSB-EP852881HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2198-2431aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: RSVVGVVNQP IDVTVTLKLG GYEPLFTMSA QQPSIIPFTA QAYEELSRQF DPQPLAMQFI SQYSPEDIVT AQIEGSSGAL WRISPPSRAQ MKRELYNGTA DITLRFTWNF...
| Schlagworte: | Mib, FAM38A, PIEZO1, Protein FAM38A, Membrane protein induced by beta-amyloid treatment, Piezo-type mechanosensitive ion... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 33.6 kD |
ab 292,00 €
Anti-PIEZO1 / FAM38A
Artikelnummer: ARG57978.100
Protein function: Pore-forming subunit of a mechanosensitive non-specific cation channel (PubMed:23479567, PubMed:23695678). Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining...
| Schlagworte: | Anti-Mib, Anti-PIEZO1, Anti-FAM38A, Anti-Protein FAM38A, Anti-Membrane protein induced by beta-amyloid treatment,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
658,00 €
Anti-PIEZO2
Artikelnummer: E-AB-17942.120
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in...
| Schlagworte: | Anti-PIEZO2, Anti-C18orf30, Anti-Protein FAM38B, Anti-Piezo-type mechanosensitive ion channel component 2, PIEZO2... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Anti-PIEZO1, clone CL9714
Artikelnummer: ATA-AMAb91589.100
Protein function: Pore-forming subunit of a mechanosensitive non-specific cation channel (PubMed:23479567, PubMed:23695678). Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining...
| Schlagworte: | Anti-Mib, Anti-PIEZO1, Anti-FAM38A, Anti-Protein FAM38A, Anti-Membrane protein induced by beta-amyloid treatment,... |
| Anwendung: | WB, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 358,00 €
Anti-PIEZO2
Artikelnummer: ATA-HPA015986.100
Protein function: Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added...
| Schlagworte: | Anti-PIEZO2, Anti-C18orf30, Anti-Protein FAM38B, Anti-Piezo-type mechanosensitive ion channel component 2 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
Anti-PIEZO2
Artikelnummer: ATA-HPA031975.100
Protein function: Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added...
| Schlagworte: | Anti-PIEZO2, Anti-C18orf30, Anti-Protein FAM38B, Anti-Piezo-type mechanosensitive ion channel component 2 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
Dooku1
Artikelnummer: Cay39161-10
Dooku1 is an antagonist of yoda1-activated Piezo1 ion channels (IC50 = 1.3 µM in HEK293 cells expressing the human receptor). It is selective for Piezo1 activated by yoda1 (Cay-21904) over constituitively active Piezo1, transient receptor potential vanilloid 4 (TRPV4), and transient receptor potential canonical 4...
| Schlagworte: | 2-[[(2,6-dichlorophenyl)methyl]thio]-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole |
| Anwendung: | Yoda1-activated Piezo1 antagonist |
| CAS | 2253744-54-4 |
| MW: | 326.2 D |
ab 133,00 €
NEU
Anti-At2g48060/At2g48040/At2g48050
Artikelnummer: CSB-PA571430XA01DOA.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-Piezo-type mechanosensitive ion channel homolog, At2g48060/At2g48040/At2g48050 Antibody |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Arabidopsis thaliana (Mouse-ear cress) |
ab 1.529,00 €