Zu "K22128" wurden 13 Artikel gefunden!
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Dooku1
Artikelnummer: Cay39161-10
Dooku1 is an antagonist of yoda1-activated Piezo1 ion channels (IC50 = 1.3 µM in HEK293 cells expressing the human receptor). It is selective for Piezo1 activated by yoda1 (Cay-21904) over constituitively active Piezo1, transient receptor potential vanilloid 4 (TRPV4), and transient receptor potential canonical 4...
| Schlagworte: | 2-[[(2,6-dichlorophenyl)methyl]thio]-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole |
| Anwendung: | Yoda1-activated Piezo1 antagonist |
| CAS | 2253744-54-4 |
| MW: | 326.2 D |
ab 130,00 €
Yoda1
Artikelnummer: Cay21904-1
Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 µM for murine and human Piezo1-transfected HEK293T cells, respectively). It is selective for Piezo1 as it elicits Ca2+ flux in Piezo1- but not Piezo2-transfected HEK293T cells. Yoda1 slows the inactivation phase of murine Piezo1 transient currents and...
| Schlagworte: | 2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-pyrazine |
| Anwendung: | Piezo1 agonist |
| CAS | 448947-81-7 |
| MW: | 355.3 D |
ab 44,00 €
Anti-PIEZO1 / FAM38A
Artikelnummer: ARG57978.100
Protein function: Pore-forming subunit of a mechanosensitive non-specific cation channel (PubMed:23479567, PubMed:23695678). Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining...
| Schlagworte: | Anti-Mib, Anti-PIEZO1, Anti-FAM38A, Anti-Protein FAM38A, Anti-Membrane protein induced by beta-amyloid treatment,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
Anti-PIEZO2
Artikelnummer: E-AB-17942.120
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in...
| Schlagworte: | Anti-PIEZO2, Anti-C18orf30, Anti-Protein FAM38B, Anti-Piezo-type mechanosensitive ion channel component 2, PIEZO2... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
Anti-PIEZO1
Artikelnummer: G-CAB4340.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 352,00 €
Anti-PIEZO1, clone CL9714
Artikelnummer: ATA-AMAb91589.100
Protein function: Pore-forming subunit of a mechanosensitive non-specific cation channel (PubMed:23479567, PubMed:23695678). Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining...
| Schlagworte: | Anti-Mib, Anti-PIEZO1, Anti-FAM38A, Anti-Protein FAM38A, Anti-Membrane protein induced by beta-amyloid treatment,... |
| Anwendung: | WB, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 335,00 €
Anti-PIEZO2
Artikelnummer: ATA-HPA015986.100
Protein function: Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added...
| Schlagworte: | Anti-PIEZO2, Anti-C18orf30, Anti-Protein FAM38B, Anti-Piezo-type mechanosensitive ion channel component 2 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €
Anti-PIEZO2
Artikelnummer: ATA-HPA031975.100
Protein function: Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added...
| Schlagworte: | Anti-PIEZO2, Anti-C18orf30, Anti-Protein FAM38B, Anti-Piezo-type mechanosensitive ion channel component 2 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €
Human PIEZO-1 (Piezo-type mechanosensitive ion channel...
Artikelnummer: ELK-ELK0343.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PIEZO-1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PIEZO-1....
| Schlagworte: | Mib, PIEZO1, FAM38A, Protein FAM38A, Membrane protein induced by beta-amyloid treatment, Piezo-type mechanosensitive ion... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 352,00 €
Human PIEZO1 (Piezo-type mechanosensitive ion channel...
Artikelnummer: G-HUFI04961.96
Human PIEZO1 (Piezo-type mechanosensitive ion channel component 1) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Human PIEZO1 (Piezo-type mechanosensitive ion channel component 1) in serum, plasma & cell culture supernatant samples....
| Schlagworte: | Mib, FAM38A, PIEZO1, Protein FAM38A, Membrane protein induced by beta-amyloid treatment, Piezo-type mechanosensitive ion... |
| Anwendung: | Sandwich ELISA |
| Spezies-Reaktivität: | human |
641,00 €
PIEZO2 PrEST Antigen
Artikelnummer: ATA-APrEST72677.100
Protein function: Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
| Schlagworte: | PIEZO2, C18orf30, Protein FAM38B, Piezo-type mechanosensitive ion channel component 2 |
| Anwendung: | Control antigen |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
247,00 €
PIEZO2 PrEST Antigen
Artikelnummer: ATA-APrEST90769.100
Protein function: Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
| Schlagworte: | PIEZO2, C18orf30, Protein FAM38B, Piezo-type mechanosensitive ion channel component 2 |
| Anwendung: | Control antigen |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
247,00 €