Zu "K21357" wurden 51 Artikel gefunden!
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Anti-ULK1 (Phospho-Ser757) Rabbit (Clone RM48
Artikelnummer: Cay42818-100
Unc-51-like autophagy activating kinase 1 (ULK1), also known as autophagy-related 1 homolog (ATG1), is a kinase involved in initiating autophagy. It is composed of an N-terminal kinase domain, a proline serine-rich domain, and two C-terminal microtubule-interacting and transporter (MIT) domains. ULK1 forms a complex...
| Schlagworte: | ATG1, Autophagy-related 1 Homolog, Unc-51-like Autophagy Activating Kinase 1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
512,00 €
ULK-101
Artikelnummer: TGM-T5403-100mg
Description: ULK-101 is a potent and selective inhibitor of ULK1 (IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy. Target: Autophagy. Smiles: Fc1ccc(cc1)-c1cnc2c(cnn2c1)-c1csc(c1)C(=O)N[C@@H](C1CC1)C(F)(F)F. References: Martin KR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and...
| Anwendung: | ULK1 / ULK2 inhibitor |
| CAS | 2443816-45-1 |
| MW: | 460.45 D |
ab 112,00 €
BL-918
Artikelnummer: TGM-T8322-100mg
Description: BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM. Target: Autophagy. Smiles: Fc1ccc(NC(=O)[C@H](NC(=S)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2ccccc2)c(F)c1. References: Ouyang L, et al. Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective...
| Anwendung: | ULK1 activator |
| CAS | 2101517-69-3 |
| MW: | 533.44 D |
ab 45,00 €
LYN-1604
Artikelnummer: TGM-T4123-100mg
Description: LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. Target: Apoptosis, Autophagy. Smiles: C(CN1CCN(C(CN(CC(C)C)CC(C)C)=O)CC1)(OCC2=CC3=C(C=C2)C=CC=C3)C4=C(Cl)C=C(Cl)C=C4. References: Zhang L, Fu L, Zhang S, Zhang J,...
| Schlagworte: | LYN1604 |
| Anwendung: | ULK1 activator |
| CAS | 2088939-99-3 |
| MW: | 584.62 D |
ab 105,00 €
ULK, active human recombinant protein
Artikelnummer: BPS-40099
Human ULK1 (GenBank Accession No. NM_003565), amino-acids 2-end with N-terminal DDDDK tag (FLAG), MW = 113 kDa, expressed in FreeStyle 293-F cells Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
| Schlagworte: | ATG1, hATG1, Unc-51-like kinase 1, Autophagy-related protein 1 homolog, Serine/threonine-protein kinase ULK1, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 113 kD |
611,00 €
Anti-UNG1
Artikelnummer: 600-401-FV0
Anti-UNG1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with UNG1 from other sources has not been determined. Protein function: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-...
| Schlagworte: | Anti-ULK1, Anti-ATG1, Anti-hATG1, Anti-KIAA0722, EC=2.7.11.1, Anti-Unc-51-like kinase 1, Anti-Autophagy-related protein 1... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
834,00 €
LYN-1604
Artikelnummer: Cay24007-1
LYN-1604 is an activator of unc-51-like kinase 1 (ULK1, EC50 = 18.94 nM). It increases Beclin 1, LC3-II, and total LC3 protein levels and reduces levels of p62 in human MDA-MB-231 triple-negative breast cancer (TNBC) cells in a concentration-dependent manner, indicating an increase in autophagy. It also increases...
| Schlagworte: | 2-[bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(2-naphthalenylmethoxy)ethyl]-1-piperazinyl]-ethanone |
| Anwendung: | ULK1 activator |
| CAS | 2088939-99-3 |
| MW: | 584.6 D |
ab 111,00 €
Anti-phospho-ULK1 (Ser556)
Artikelnummer: NSJ-F48759-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex...
| Schlagworte: | Anti-phospho-ATG1, Anti-phospho-ULK1, Anti-phospho-hATG1, Anti-phospho-KIAA0722, EC=2.7.11.1, Anti-phospho-Unc-51-like... |
| Anwendung: | IF, Dot Blot, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 350,00 €
Anti-ULK1
Artikelnummer: NSJ-F47190-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ULK1 is a target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). [UniProt] Protein function: Serine/threonine-protein...
| Schlagworte: | Anti-ATG1, Anti-ULK1, Anti-hATG1, Anti-KIAA0722, EC=2.7.11.1, Anti-Unc-51-like kinase 1, Anti-Autophagy-related protein 1... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 350,00 €
Anti-phospho-ULK1 (Ser467)
Artikelnummer: NSJ-F48812-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ULK1 is involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1...
| Schlagworte: | Anti-phospho-ATG1, Anti-phospho-ULK1, Anti-phospho-hATG1, Anti-phospho-KIAA0722, EC=2.7.11.1, Anti-phospho-Unc-51-like... |
| Anwendung: | Dot Blot, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 350,00 €
Anti-phospho-ULK1 (Ser317)
Artikelnummer: NSJ-F48758-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex...
| Schlagworte: | Anti-phospho-ATG1, Anti-phospho-ULK1, Anti-phospho-hATG1, Anti-phospho-KIAA0722, EC=2.7.11.1, Anti-phospho-Unc-51-like... |
| Anwendung: | Dot Blot, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 350,00 €
Anti-ULK1
Artikelnummer: NSJ-F51530-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ULK1/ATG1 is involved in autophagy. It is required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex....
| Schlagworte: | Anti-ATG1, Anti-ULK1, Anti-hATG1, Anti-KIAA0722, EC=2.7.11.1, Anti-Unc-51-like kinase 1, Anti-Autophagy-related protein 1... |
| Anwendung: | WB, IHC, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 350,00 €