Zu "K20995" wurden 52 Artikel gefunden!
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Notch 3, His, Human
Artikelnummer: GSC-Z05703-100
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring...
| Schlagworte: | NOTCH3, Neurogenic locus notch homolog protein 3 |
| Ursprungsart: | human |
| MW: | 30.18 kD |
ab 524,00 €
Notch 3 hFc Chimera, Human
Artikelnummer: GSC-Z05704-100
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring...
| Schlagworte: | NOTCH3, Neurogenic locus notch homolog protein 3 |
| Ursprungsart: | human |
| MW: | 71.53 kD |
ab 524,00 €
![Notch 3[Biotin], His & Avi, Human](https://www.biomol.com/media/image/ef/ca/ce/GSC-Z04574-100_200x200.png "Notch 3[Biotin], His & Avi, Human")
Notch 3[Biotin], His & Avi, Human
Artikelnummer: GSC-Z04574-100
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring...
| Schlagworte: | NOTCH3, Neurogenic locus notch homolog protein 3 |
| Ursprungsart: | human |
| MW: | 47.7 kD |
ab 887,00 €
Anti-NOTCH3, C-terminal
Artikelnummer: ARG63870.100
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
| Schlagworte: | Anti-NOTCH3 |
| Anwendung: | ELISA, IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
871,00 €
Human NOTCH3 ELISA Kit
Artikelnummer: G-HUFI01943.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-NOTCH3
Artikelnummer: NSJ-R35352-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: CADASIL, CASIL Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released...
| Schlagworte: | Anti-NOTCH3, NOTCH3 Antibody |
| Anwendung: | IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
FLI-06
Artikelnummer: Cay21272-50
FLI-06 is a first-of-its-kind inhibitor of Notch signaling (EC50 = 2.3 µM) that acts upstream of alpha-secretase and beta-secretase cleavage. It disrupts the intracellular trafficking and processing of the Notch signaling pathway, inhibiting general secretion at a stage before exit from the endoplasmic reticulum...
| Schlagworte: | 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylic acid, cyclohexyl ester |
| Anwendung: | Notch signaling inhibitor |
| CAS | 313967-18-9 |
| MW: | 438.5 D |
ab 122,00 €
Anti-NOTCH3, clone 487CT6.9.2
Artikelnummer: NSJ-F40367-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in...
| Schlagworte: | Anti-NOTCH3, Anti-Neurogenic locus notch homolog protein 3, NOTCH3 Antibody |
| Anwendung: | WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-NOTCH3
Artikelnummer: NSJ-F49506-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural...
| Schlagworte: | Anti-NOTCH3, NOTCH3 Antibody |
| Anwendung: | WB, IF, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-NOTCH3
Artikelnummer: ARG59072.100
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of...
| Schlagworte: | Anti-NOTCH3 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
707,00 €
Anti-NOTCH3
Artikelnummer: ATA-HPA044392.100
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of...
| Schlagworte: | Anti-NOTCH3 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
CB-103
Artikelnummer: Cay36293-1
CB-103 is an inhibitor of Notch signaling. It binds to the b-trefoil domain (BTD) of recombination signal binding protein for immunoglobulin kappa J region (RBPJ) and inhibits the assembly of the RBPJ-Notch intracellular domain (NICD) transcription complex. CB-103 inhibits ligand-induced Notch signaling in HeLa...
| Schlagworte: | 6-[4-(1,1-dimethylethyl)phenoxy]-3-pyridinamine |
| Anwendung: | Notch signaling inhibitor |
| CAS | 218457-67-1 |
| MW: | 242.3 D |
ab 49,00 €