Zu "K20995" wurden 54 Artikel gefunden!
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Anti-NOTCH3, C-terminal
Artikelnummer: ARG63870.100
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
| Schlagworte: | Anti-NOTCH3 |
| Anwendung: | ELISA, IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
871,00 €
Human NOTCH3 ELISA Kit
Artikelnummer: G-HUFI01943.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-NOTCH3
Artikelnummer: NSJ-R35352-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: CADASIL, CASIL Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released...
| Schlagworte: | Anti-NOTCH3, NOTCH3 Antibody |
| Anwendung: | IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
FLI-06
Artikelnummer: Cay21272-50
FLI-06 is a first-of-its-kind inhibitor of Notch signaling (EC50 = 2.3 µM) that acts upstream of alpha-secretase and beta-secretase cleavage. It disrupts the intracellular trafficking and processing of the Notch signaling pathway, inhibiting general secretion at a stage before exit from the endoplasmic reticulum...
| Schlagworte: | 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylic acid, cyclohexyl ester |
| Anwendung: | Notch signaling inhibitor |
| CAS | 313967-18-9 |
| MW: | 438.5 D |
ab 126,00 €
Anti-NOTCH3, clone 487CT6.9.2
Artikelnummer: NSJ-F40367-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in...
| Schlagworte: | Anti-NOTCH3, Anti-Neurogenic locus notch homolog protein 3, NOTCH3 Antibody |
| Anwendung: | WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-NOTCH3
Artikelnummer: NSJ-F49506-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural...
| Schlagworte: | Anti-NOTCH3, NOTCH3 Antibody |
| Anwendung: | WB, IF, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-NOTCH3
Artikelnummer: ARG59072.100
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of...
| Schlagworte: | Anti-NOTCH3 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
707,00 €
Anti-NOTCH3
Artikelnummer: ATA-HPA044392.100
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of...
| Schlagworte: | Anti-NOTCH3 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
CB-103
Artikelnummer: Cay36293-1
CB-103 is an inhibitor of Notch signaling. It binds to the b-trefoil domain (BTD) of recombination signal binding protein for immunoglobulin kappa J region (RBPJ) and inhibits the assembly of the RBPJ-Notch intracellular domain (NICD) transcription complex. CB-103 inhibits ligand-induced Notch signaling in HeLa...
| Schlagworte: | 6-[4-(1,1-dimethylethyl)phenoxy]-3-pyridinamine |
| Anwendung: | Notch signaling inhibitor |
| CAS | 218457-67-1 |
| MW: | 242.3 D |
ab 51,00 €
IMR-1A
Artikelnummer: Cay37432-50
IMR-1A is an inhibitor of Notch ternary complex formation (IC50 = 0.5 µM) and an active metabolite of the mastermind-like 1 (MAM-1) chromatin recruitment inhibitor IMR-1 (Cay-27920). It binds to the intracellular domain of Notch (Kd = 2.9 µM) and disrupts the protein-protein interactions between Notch and MAM-1 and...
| Schlagworte: | 2-[2-methoxy-4-[(4-oxo-2-thioxo-5-thiazolidinylidene)methyl],phenoxy]-acetic acid |
| Anwendung: | Notch ternary complex formation inhibitor |
| CAS | 331862-41-0 |
| MW: | 325.4 D |
ab 95,00 €
Human NOTCH3 Protein, hFc Tag
Artikelnummer: DIM-PME100646.10
Recombinant human NOTCH3 protein with C-terminal human Fc tag. NOTCH3(Ala40-Glu467) hFc(Glu99-Ala330), Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543). Upon ligand activation through the released notch...
| Schlagworte: | CADASIL, CADASIL1, CASIL, IMF2, LMNS |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 70.9 kD |
ab 120,00 €
Anti-NOTCH3
Artikelnummer: CSB-PA586591.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NOTCH3. Antigen Species: Human
| Schlagworte: | Anti-NOTCH3, CADASIL antibody, CASIL antibody, NOTC3_HUMAN antibody, Notch 3 antibody, Notch 3 intracellular domain... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €