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Zu "K20994" wurden 34 Artikel gefunden!
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Artikelnummer: NSJ-RQ5542
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Neurogenic locus notch homolog protein 2 also known as notch 2 is a protein that in humans is encoded by the NOTCH2 gene. It is mapped to 1p12. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural...
Schlagworte: | , NOTCH2 Antibody |
Anwendung: | WB, Direct ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: Cay37432-10
IMR-1A is an inhibitor of Notch ternary complex formation (IC50 = 0.5 µM) and an active metabolite of the mastermind-like 1 (MAM-1) chromatin recruitment inhibitor IMR-1 (Cay-27920). It binds to the intracellular domain of Notch (Kd = 2.9 µM) and disrupts the protein-protein interactions between Notch and MAM-1 and...
Schlagworte: | 2-[2-methoxy-4-[(4-oxo-2-thioxo-5-thiazolidinylidene)methyl],phenoxy]-acetic acid |
Anwendung: | Notch ternary complex formation inhibitor |
CAS | 331862-41-0 |
MW: | 325.4 D |
ab 82,00 €
Artikelnummer: A302-084A
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: | Anti-NOTCH2 |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: A302-083A
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: | Anti-NOTCH2 |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: 100-401-406
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: | Anti-NOTCH2 |
Anwendung: | ELISA, IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
684,00 €
Artikelnummer: 100-401-408S
This antiserum is directed against human NOTCH 2. Based on sequences, we expect this antibody to react as well with rat and mouse NOTCH 2. Only one amino acid difference (conservative) occurs in mouse and rat. The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved...
Schlagworte: | Anti-NOTCH2 |
Anwendung: | ELISA, IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
180,00 €
Artikelnummer: IHC-00539
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: | Anti-NOTCH2, Anti-NOTCH-2, Anti-neurogenic locus notch homolog protein 2, Anti-AGS2. |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
-10 %
Artikelnummer: AG-20B-0052-C100
Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development...
Schlagworte: | Anti-NOTCH2, Anti-NOTCH-2, Anti-neurogenic locus notch homolog protein 2, Anti-AGS2. |
Anwendung: | FC |
Wirt: | Rat |
Spezies-Reaktivität: | human, mouse |
319,00 €
287,10 €
-10 %
Artikelnummer: AG-20B-0052B-C100
Recognizes human and mouse endogenous Notch-2 receptor. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1,...
Schlagworte: | Neurogenic Locus Notch Homolog Protein 2, Motch B |
Anwendung: | FC |
Wirt: | rat |
Spezies-Reaktivität: | human, mouse |
347,00 €
312,30 €
Artikelnummer: ARG23293.100
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: | Anti-Notch2 |
Anwendung: | FC |
Wirt: | Hamster |
Spezies-Reaktivität: | mouse, rat |
640,00 €
Artikelnummer: G-HUFI01879.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: 100-401-408
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: | Anti-NOTCH2 |
Anwendung: | ELISA, IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
684,00 €