Zu "K20994" wurden 56 Artikel gefunden!
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Anti-Notch2
Artikelnummer: A302-084A
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
| Schlagworte: | Anti-NOTCH2 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-Notch2
Artikelnummer: A302-083A
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
| Schlagworte: | Anti-NOTCH2 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-Notch2, intracellular (human specific)
Artikelnummer: 100-401-406
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
| Schlagworte: | Anti-NOTCH2 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
733,00 €
Anti-NOTCH 2 (Cleaved N terminal) (Human specific)
Artikelnummer: 100-401-408S
This antiserum is directed against human NOTCH 2. Based on sequences, we expect this antibody to react as well with rat and mouse NOTCH 2. Only one amino acid difference (conservative) occurs in mouse and rat. The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved...
| Schlagworte: | Anti-NOTCH2 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
180,00 €
Anti-Notch2 (IHC)
Artikelnummer: IHC-00539
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
| Schlagworte: | Anti-NOTCH2, Anti-NOTCH-2, Anti-neurogenic locus notch homolog protein 2, Anti-AGS2. |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-Notch2, clone 16F11
Artikelnummer: AG-20B-0052-C100
Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development...
| Schlagworte: | Anti-NOTCH2, Anti-NOTCH-2, Anti-neurogenic locus notch homolog protein 2, Anti-AGS2. |
| Anwendung: | FC |
| Wirt: | Rat |
| Spezies-Reaktivität: | human, mouse |
319,00 €
Anti-Notch2 , clone 16F11, Biotin conjugated
Artikelnummer: AG-20B-0052B-C100
Recognizes human and mouse endogenous Notch-2 receptor. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1,...
| Schlagworte: | Neurogenic Locus Notch Homolog Protein 2, Motch B |
| Anwendung: | FC |
| Wirt: | rat |
| Spezies-Reaktivität: | human, mouse |
347,00 €
Anti-Notch2, clone HMN2-35
Artikelnummer: ARG23293.100
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
| Schlagworte: | Anti-Notch2 |
| Anwendung: | FC |
| Wirt: | Hamster |
| Spezies-Reaktivität: | mouse, rat |
690,00 €
Human NOTCH2 ELISA Kit
Artikelnummer: G-HUFI01879.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-Notch2, cleaved, NT
Artikelnummer: 100-401-408
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
| Schlagworte: | Anti-NOTCH2 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
733,00 €
FLI-06
Artikelnummer: Cay21272-25
FLI-06 is a first-of-its-kind inhibitor of Notch signaling (EC50 = 2.3 µM) that acts upstream of alpha-secretase and beta-secretase cleavage. It disrupts the intracellular trafficking and processing of the Notch signaling pathway, inhibiting general secretion at a stage before exit from the endoplasmic reticulum...
| Schlagworte: | 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylic acid, cyclohexyl ester |
| Anwendung: | Notch signaling inhibitor |
| CAS | 313967-18-9 |
| MW: | 438.5 D |
ab 122,00 €
Anti-Notch 2
Artikelnummer: ARG58767.100
Protein function: Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes...
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €