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Anti-NOTCH2
Anti-NOTCH2

Artikelnummer: NSJ-RQ5542

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Neurogenic locus notch homolog protein 2 also known as notch 2 is a protein that in humans is encoded by the NOTCH2 gene. It is mapped to 1p12. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural...
Schlagworte: , NOTCH2 Antibody
Anwendung: WB, Direct ELISA
Wirt: Rabbit
Spezies-Reaktivität: human
755,00 €
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IMR-1A
IMR-1A

Artikelnummer: Cay37432-10

IMR-1A is an inhibitor of Notch ternary complex formation (IC50 = 0.5 µM) and an active metabolite of the mastermind-like 1 (MAM-1) chromatin recruitment inhibitor IMR-1 (Cay-27920). It binds to the intracellular domain of Notch (Kd = 2.9 µM) and disrupts the protein-protein interactions between Notch and MAM-1 and...
Schlagworte: 2-[2-methoxy-4-[(4-oxo-2-thioxo-5-thiazolidinylidene)methyl],phenoxy]-acetic acid
Anwendung: Notch ternary complex formation inhibitor
CAS 331862-41-0
MW: 325.4 D
ab 82,00 €
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Anti-Notch2
Anti-Notch2

Artikelnummer: A302-084A

Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: Anti-NOTCH2
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-Notch2
Anti-Notch2

Artikelnummer: A302-083A

Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: Anti-NOTCH2
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-Notch2, intracellular (human specific)
Anti-Notch2, intracellular (human specific)

Artikelnummer: 100-401-406

Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: Anti-NOTCH2
Anwendung: ELISA, IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: human
684,00 €
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Anti-NOTCH 2 (Cleaved N terminal) (Human specific)
Anti-NOTCH 2 (Cleaved N terminal) (Human specific)

Artikelnummer: 100-401-408S

This antiserum is directed against human NOTCH 2. Based on sequences, we expect this antibody to react as well with rat and mouse NOTCH 2. Only one amino acid difference (conservative) occurs in mouse and rat. The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved...
Schlagworte: Anti-NOTCH2
Anwendung: ELISA, IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: human
180,00 €
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Anti-Notch2 (IHC)
Anti-Notch2 (IHC)

Artikelnummer: IHC-00539

Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: Anti-NOTCH2, Anti-NOTCH-2, Anti-neurogenic locus notch homolog protein 2, Anti-AGS2.
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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-10 %
Anti-Notch2, clone 16F11
Anti-Notch2, clone 16F11

Artikelnummer: AG-20B-0052-C100

Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development...
Schlagworte: Anti-NOTCH2, Anti-NOTCH-2, Anti-neurogenic locus notch homolog protein 2, Anti-AGS2.
Anwendung: FC
Wirt: Rat
Spezies-Reaktivität: human, mouse
319,00 € 287,10 €
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-10 %
Anti-Notch2 , clone 16F11, Biotin conjugated
Anti-Notch2 , clone 16F11, Biotin conjugated

Artikelnummer: AG-20B-0052B-C100

Recognizes human and mouse endogenous Notch-2 receptor. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1,...
Schlagworte: Neurogenic Locus Notch Homolog Protein 2, Motch B
Anwendung: FC
Wirt: rat
Spezies-Reaktivität: human, mouse
347,00 € 312,30 €
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Anti-Notch2, clone HMN2-35
Anti-Notch2, clone HMN2-35

Artikelnummer: ARG23293.100

Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: Anti-Notch2
Anwendung: FC
Wirt: Hamster
Spezies-Reaktivität: mouse, rat
640,00 €
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Human NOTCH2 ELISA Kit
Human NOTCH2 ELISA Kit

Artikelnummer: G-HUFI01879.96

Anwendung: ELISA
Spezies-Reaktivität: human
641,00 €
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Anti-Notch2, cleaved, NT
Anti-Notch2, cleaved, NT

Artikelnummer: 100-401-408

Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of...
Schlagworte: Anti-NOTCH2
Anwendung: ELISA, IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: human
684,00 €
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