Zu "K19882" wurden 31 Artikel gefunden!
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ABC99
Artikelnummer: Cay25858-1
ABC99 is an N-hydroxyhydantoin (NHH) carbamate that inhibits the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM). It preserves Wnt3A signaling in the presence of NOTUM (EC50 = 89 nM in a cell-based reporter assay).Formal Name:...
| Schlagworte: | 7-(4-chlorobenzyl)-1,3-dioxohexahydroimidazo[1,5-a]pyrazin-2(3H)-yl-2,3-dihydro-4H-benzo[b][1,4]oxazine-4-carboxylate |
| Anwendung: | NOTUM inhibitor |
| CAS | 2331255-53-7 |
| MW: | 456.9 D |
ab 126,00 €
Human NOTUM / Protein notum homolog ELISA Kit
Artikelnummer: G-HUFI01515.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-NOTUM
Artikelnummer: 600-401-DD7
Anti-NOTUM Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NOTUM from other sources has not been determined. Protein function: May deacetylate GlcNAc residues on cell surface glycans. [The UniProt Consortium]
| Schlagworte: | Anti-NOTUM, EC=3.-.-.-, Anti-Protein notum homolog |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Palmitoleoyl-protein carboxylesterase NOTUM (NOTUM),...
Artikelnummer: CSB-EP747435HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 20-496aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: SEGRKTWRRR GQQPPPPPRT EAAPAAGQPV ESFPLDFTAV EGNMDSFMAQ VKSLAQSLYP CSAQQLNEDL RLHLLLNTSV TCNDGSPAGY YLKESRGSRR WLLFLEGGWY CFNRENCDSR...
| Schlagworte: | hNOTUM, Palmitoleoyl-protein carboxylesterase NOTUM, Recombinant Human Palmitoleoyl-protein carboxylesterase NOTUM (NOTUM) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 57.8 kD |
ab 292,00 €
NOTUM Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01825-100ug
Description: Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors. NOTUM Protein, Human, Recombinant (His) is expressed in E....
| Schlagworte: | NOTUM, hNOTUM, Palmitoleoyl-protein carboxylesterase NOTUM |
| MW: | 57.8 kD |
ab 266,00 €
ARUK3001185
Artikelnummer: TGM-T60537-100mg
Description: ARUK3001185 (Compound 8l) is a potent, selective, orally active, and brain-penetrant Notum inhibitor (IC50 = 6.7 nM), suitable for oral dosing in rodent models of disease [1]. Target: Others. Smiles: C(F)(F)(F)C1=C(Cl)C(=CC=C1Cl)N2C=CN=N2
| Anwendung: | NOTUM inhibitor |
| CAS | 2411969-39-4 |
| MW: | 282.05 D |
ab 89,00 €
NEU
Anti-Notum
Artikelnummer: CSB-PA784750XA01DLU.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-dNOTUM, Anti-Protein Notum, Anti-Protein wingful, Anti-Palmitoleoyl-protein carboxylesterase NOTUM, Notum Antibody |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Drosophila melanogaster (Fruit fly) |
1.529,00 €
NOTUM Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01825-10ug
Description: Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors. NOTUM Protein, Human, Recombinant (His) is expressed in E....
| Schlagworte: | Palmitoleoyl-protein carboxylesterase NOTUM , hNOTUM , NOTUM |
| MW: | 57.8 kD |
ab 99,00 €
Anti-PAE12
Artikelnummer: CSB-PA446474XA01DOA.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-Pectin acetylesterase 12, PAE12 Antibody |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Arabidopsis thaliana (Mouse-ear cress) |
1.529,00 €
ARUK3001185
Artikelnummer: Cay37113-1
ARUK3001185 is an inhibitor of palmitoleoyl-protein carboxylesterase NOTUM (IC50 = 6.7 nM), an enzyme involved in the deacylation of Wnt. It is selective for NOTUM over a panel of 39 serine hydrolases and 485 kinases, including casein kinase 1 (CK1) and glycogen synthase kinase 3 (GSK3), at 10 µM and a panel of 47...
| Schlagworte: | 1-Phenyl-1H-1,2,3-triazole 1, 1-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1H-1,2,3-triazole |
| Anwendung: | NOTUM inhibitor |
| CAS | 2411969-39-4 |
| MW: | 282.1 D |
ab 78,00 €
Mouse Protein notum homolog (NOTUM) ELISA kit
Artikelnummer: CSB-EL015955MO.48
Sample Types: serum, plasma, tissue homogenates, cell culture supernates Detection Range: 0.156 ng/mL-10 ng/mL Sensitivity: 0.039 ng/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Carboxylesterase that acts as a key negative...
| Schlagworte: | Palmitoleoyl-protein carboxylesterase NOTUM |
| Anwendung: | ELISA, Sandwich ELISA |
| Spezies-Reaktivität: | mouse |
ab 581,00 €
Human Protein notum homolog (NOTUM) ELISA kit
Artikelnummer: CSB-EL015955HU.48
Sample Types: serum, plasma, tissue homogenates Detection Range: 1.56 ng/mL-100 ng/mL Sensitivity: 0.39 ng/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Carboxylesterase that acts as a key negative regulator of the Wnt...
| Schlagworte: | hNOTUM, Palmitoleoyl-protein carboxylesterase NOTUM |
| Anwendung: | ELISA, Sandwich ELISA |
| Spezies-Reaktivität: | human |
ab 581,00 €