Zu "K19801" wurden 24 Artikel gefunden!
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NEU
UCB 9608
Artikelnummer: Cay43027-10
UCB 9608 is an inhibitor of PI4KIIIbeta (IC50 = 11 nM). It is selective for PI4KIIIbeta over 8 other phosphatidylinositol kinases at 10 µM. UCB 9608 inhibits the mixed lymphocyte reaction in isolated human peripheral blood mononuclear cells (PBMCs, IC50 = 37 nM). It increases heart allograft survival in mice when...
| Schlagworte: | (3S)-4-(6-amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methyl-1-piperazinecarboxamide |
| Anwendung: | PI4KIII beta (PI4KB, phosphatidylinositol 4-kinase B) inhibitor |
| CAS | 1616413-96-7 |
| MW: | 410.48 D |
ab 55,00 €
PIK-93
Artikelnummer: TGM-T2616-100mg
Description: PIK-93, the first potent synthetic PI4K inhibitor, exhibits an IC50 of 19 nM and also inhibits PI3Kalpha with an IC50 of 39 nM. Target: PI3K, mTOR, ATM/ATR, PI4K, DNA-PK, HSV, Carbonic Anhydrase, Virus Protease. Smiles: CC(=O)Nc1nc(C)c(s1)-c1ccc(Cl)c(c1)S(=O)(=O)NCCO. References: Knight ZA, Cell,...
| Schlagworte: | PIK 93 |
| Anwendung: | PI4K-beta inhibitor |
| CAS | 593960-11-3 |
| MW: | 389.88 D |
ab 38,00 €
PI4KIIIbeta Inhibitor 3
Artikelnummer: Cay39530-1
PI4KIIIbeta inhibitor 3 is an inhibitor of PI4KIIIbeta (IC50 = 19 nM). It is approximately 100-fold selective for PI4KIIIbeta over PI4KIIalpha, PI4KIIbeta, and PI4KIIIalpha, PI3Kalpha, PI3Kbeta, PI3Kgamma, and PI3Kdelta, and PI3KC3, as well as 100-500-fold selective over PI3KC2alpha, PI3KC2beta, and...
| Schlagworte: | 4-[5-amino-2-(3-pyridinyl)thiazolo[5,4-d]pyrimidin-7-yl]-N -(4-methylphenyl)-1-piperazinecarboxamide |
| Anwendung: | Phosphatidylinositol 4-kinase beta (PI4KB) inhibitor |
| CAS | 1245319-54-3 |
| MW: | 446.5 D |
ab 82,00 €
PI4KIII beta inhibitor 3
Artikelnummer: TGM-T12467-1mg
Description: PI4KIII beta inhibitor 3 is a novel, highly effective inhibitor of PI4KIIIbeta with an IC50 of 5.7 nM. Target: PI3K. Smiles: Cc1ccc(NC(=O)N2CCN(CC2)c2nc(N)nc3sc(nc23)-c2cccnc2)cc1. References: Jean Herman, et al. Autoimmune and inflammatory disorder therapy. From PCT Int. Appl. (2013), WO 2013034738 A1
| Anwendung: | PI4KIII beta inhibitor |
| CAS | 1245319-54-3 |
| MW: | 446.53 D |
ab 251,00 €
PIK-93
Artikelnummer: Cay10009212-10
PIK-93 is an inhibitor of phosphatidylinositol 4-kinase IIIbeta (PI4KIIIbeta, IC50 = 19 nM). It is selective for PI4KIIIbeta over PI4KIIIalpha and PI4KIIalpha (IC50s = 1,100 and >100,000 nM, respectively). However, it also inhibits the PI3K catalytic subunits (IC50s = 39, 590, 120, and 16 nM for p110alpha, p110beta,...
| Schlagworte: | N-[5-[4-chloro-3-[[(2-hydroxyethyl)amino]sulfonyl]phenyl]-4-methyl-2-thiazolyl]-acetamide |
| Anwendung: | PI4K-beta inhibitor |
| CAS | 593960-11-3 |
| MW: | 389.9 D |
ab 44,00 €
Anti-PI4KB
Artikelnummer: A303-733A
Protein function: Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking....
| Schlagworte: | Anti-NPIK, Anti-PI4KB, Anti-PI4K92, Anti-PIK4CB, Anti-PI4Kbeta, Anti-PI4K-beta, EC=2.7.1.67, Anti-PtdIns 4-kinase beta,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-PI4KB
Artikelnummer: A303-734A
Protein function: Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking....
| Schlagworte: | Anti-NPIK, Anti-PI4KB, Anti-PI4K92, Anti-PIK4CB, Anti-PI4Kbeta, Anti-PI4K-beta, EC=2.7.1.67, Anti-PtdIns 4-kinase beta,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-PI4K beta
Artikelnummer: 600-401-J92
Anti-PI4K beta was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with bat, rat, primate, mouse, and human based on 100% sequence homology. Cross-reactivity with PI4K beta from other sources has not been determined....
| Schlagworte: | Anti-NPIK, Anti-PI4KB, Anti-PIK4CB, Anti-PI4K92, EC=2.7.1.67, Anti-PI4Kbeta, Anti-PI4K-beta, Anti-PtdIns 4-kinase beta,... |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
719,00 €
Anti-PI4KB
Artikelnummer: ATA-HPA006280.100
Protein function: Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking....
| Schlagworte: | Anti-NPIK, Anti-PIK4CB, Anti-PI4K92, Anti-PI4KIII, Anti-PI4Kbeta, Anti-PI4K-beta, Anti-PtdIns 4-kinase beta,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-PI4KB
Artikelnummer: ATA-HPA006281.100
Protein function: Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking....
| Schlagworte: | Anti-NPIK, Anti-PIK4CB, Anti-PI4K92, Anti-PI4KIII, Anti-PI4Kbeta, Anti-PI4K-beta, Anti-PtdIns 4-kinase beta,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 358,00 €
Anti-PIK1
Artikelnummer: CSB-PA327934XA01SVG.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-N0795, Anti-YNL267W, Anti-PI4-kinase, Anti-PtdIns-4-kinase, Anti-Phosphatidylinositol 4-kinase PIK1, PIK1 Antibody |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
ab 1.529,00 €
Anti-pik1
Artikelnummer: CSB-PA604597XA01SXV.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-pik1, Anti-PI4-kinase, EC=2.7.1.67, Anti-SPAC22E12.16c, Anti-PtdIns-4-kinase, Anti-Phosphatidylinositol 4-kinase... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
ab 1.529,00 €