Zu "K19496" wurden 105 Artikel gefunden!
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T16A(inh)-A01
Artikelnummer: Cay18518-10
Transmembrane protein 16A (TMEM16A, also known as anoctamin-1) is a calcium-activated chloride channel (CaCC) with roles in transepithelial anion transport and smooth muscle contraction. T16A(inh)-A01 is an aminophenylthiazole that inhibits transient TMEM16A-mediated chloride currents with an IC50 value of ~1 µM....
| Schlagworte: | 2-[(5-ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl)thio]-N-[4-(4-methoxyphenyl)-2-thiazolyl]-acetamide |
| Anwendung: | TMEM16A inhibitor, CaCC blocker |
| CAS | 552309-42-9 |
| MW: | 416.5 D |
ab 49,00 €
MONNA
Artikelnummer: Cay21917-1
MONNA is a selective inhibitor of anoctamin-1 (ANO1, IC50 = 0.08 µM in Xenopus oocytes), a calcium-activated chloride channel (CaCC). It is selective for ANO1 over the chloride channels bestrophin-1, chloride channel protein 2, and cystic fibrosis transmembrane conductance regulator up to 10 µM. MONNA (10 µM)...
| Schlagworte: | 2-[(4-methoxy-2-naphthalenyl)amino]-5-nitro-benzoic acid |
| Anwendung: | TMEM16A blocker |
| CAS | 1572936-83-4 |
| MW: | 338.3 D |
ab 49,00 €
Anti-DOG1 (TMEM16A)
Artikelnummer: NSJ-R31414
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Anoctamin-1 (ANO1), also known as oral cancer overexpressed 2 (ORAOV2), Tumor-amplified and overexpressed sequence 2 (TMEM16A), and Discovered on gastrointestinal stromal tumors protein 1 (DOG1) is a protein that in humans is encoded by the ANO1 gene. This gene...
| Schlagworte: | Anti-DOG1, Anti-ANO1, Anti-Anoctamin-1, Anti-Transmembrane protein 16A, Anti-Oral cancer overexpressed protein 2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-DOG1 / TMEM16A / ANO1, clone DG1/447
Artikelnummer: NSJ-V2315-100UG
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide.
| Schlagworte: | Anti-ANO1, Anti-DOG1, Anti-Anoctamin-1, Anti-Transmembrane protein 16A, Anti-Oral cancer overexpressed protein 2,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 375,00 €
Anti-DOG1 / TMEM16A / ANO1, clone DG1/447
Artikelnummer: NSJ-V2315SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free.
| Schlagworte: | Anti-ANO1, Anti-DOG1, Anti-Anoctamin-1, Anti-Transmembrane protein 16A, Anti-Oral cancer overexpressed protein 2,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
810,00 €
Anti-DOG1, clone DOG1.1
Artikelnummer: ARG58023.50
Protein function: Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a...
| Schlagworte: | Anti-ANO1, Anti-DOG1, Anti-Anoctamin-1, Anti-Transmembrane protein 16A, Anti-Oral cancer overexpressed protein 2,... |
| Anwendung: | FC, ICC, IF, IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Anti-DOG1
Artikelnummer: NSJ-F46427-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ANO1 acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity). Protein function: Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the...
| Schlagworte: | Anti-DOG1, Anti-ANO1, Anti-Anoctamin-1, Anti-Transmembrane protein 16A, Anti-Oral cancer overexpressed protein 2,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-DOG-1, clone SQab1739
Artikelnummer: ARG66250.100
Protein function: Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a...
| Schlagworte: | Anti-ANO1, Anti-DOG1, Anti-Anoctamin-1, Anti-Transmembrane protein 16A, Anti-Oral cancer overexpressed protein 2,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 460,00 €
Anti-DOG1 / TMEM16A / ANO1, clone DG1/2564R
Artikelnummer: NSJ-V7326IHC-7ML
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*. Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to...
| Schlagworte: | Anti-DOG1, Anti-ANO1, Anti-Anoctamin-1, Anti-Transmembrane protein 16A, Anti-Oral cancer overexpressed protein 2,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
810,00 €
Anti-DOG1 / TMEM16A / ANO1, clone DG1/2831R
Artikelnummer: NSJ-V7453-100UG
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Expression of DOG1/ANO1/TMEM16A protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. TMEM16A is rarely expressed in other soft tissue tumors, which, due to...
| Schlagworte: | Anti-DOG1, Anti-ANO1, Anti-Anoctamin-1, Anti-Transmembrane protein 16A, Anti-Oral cancer overexpressed protein 2,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 375,00 €
Anti-DOG1 / TMEM16A / ANO1, clone DG1/2831R
Artikelnummer: NSJ-V7453IHC-7ML
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*. Expression of DOG1/ANO1/TMEM16A protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. TMEM16A is rarely expressed in other soft tissue tumors,...
| Schlagworte: | Anti-DOG1, Anti-ANO1, Anti-Anoctamin-1, Anti-Transmembrane protein 16A, Anti-Oral cancer overexpressed protein 2,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
810,00 €
Anti-DOG1 / TMEM16A / ANO1, clone DG1/2831R
Artikelnummer: NSJ-V7453SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free. Expression of DOG1/ANO1/TMEM16A protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. TMEM16A is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to...
| Schlagworte: | Anti-DOG1, Anti-ANO1, Anti-Anoctamin-1, Anti-Transmembrane protein 16A, Anti-Oral cancer overexpressed protein 2,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
810,00 €