Zu "K19390" wurden 5 Artikel gefunden!
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Baloxavir marboxil
Artikelnummer: TGM-T6195-100mg
Description: Baloxavir marboxil (S-033188) is a novel cap-dependent endonuclease inhibitor designed for the treatment of influenza A and B virus infections. Target: Influenza Virus. Smiles: O(COC(OC)=O)C1=C2N(N([C@]3(N(C2=O)CCOC3)[H])[C@H]4C=5C(CSC=6C4=CC=CC6)=C(F)C(F)=CC5)C=CC1=O. References: Koszalka P , Tilmanis...
| Schlagworte: | S-033188 |
| Anwendung: | Targets Influenza virus polymerase acidic protein (PA) |
| CAS | 1985606-14-1 |
| MW: | 571.55 D |
ab 42,00 €
Baloxavir
Artikelnummer: TGM-T14495-100mg
Description: Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Target: Influenza Virus. Smiles: Oc1c2C(=O)N3CCOC[C@H]3N([C@@H]3c4ccccc4SCc4c(F)c(F)ccc34)n2ccc1=O. References: Omoto S, et al. Characterization of influenza virus variants induced...
| Schlagworte: | Baloxavir acid, S-033447 |
| Anwendung: | Targets Influenza virus polymerase acidic protein (PA) |
| CAS | 1985605-59-1 |
| MW: | 483.49 D |
ab 71,00 €
L-742001 Hydrochloride
Artikelnummer: TGM-T25590-100mg
Description: L-742001 Hydrochloride is an RNA polymerase inhibitor. Target: Others. Smiles: Cl.OC(=O)C(\O)=C\C(=O)C1(Cc2ccc(Cl)cc2)CCN(Cc2ccccc2)CC1. References: Yan Z, Zhang L, Fu H, Wang Z, Lin J. Design of the influenza virus inhibitors targeting the PA endonuclease using 3D-QSAR modeling, side-chain hopping, and...
| Schlagworte: | L742001 Hydrochloride, L-742001, L742001, L 742001 |
| Anwendung: | Influenza PA endonuclease inhibitor |
| CAS | 174605-64-2 |
| MW: | 450.36 D |
ab 1.820,00 €
L-742,001 (hydrochloride)
Artikelnummer: Cay40920-1
L-742,001 is an inhibitor of influenza virus PA endonuclease (IC50 = 0.5 µM), an essential subdomain of the viral RNA polymerase. It reduces viral titers in PR8 influenza-infected MDCK cells when used at a concentration of 10 µM.Formal Name:...
| Schlagworte: | 4-[4-[(4-chlorophenyl)methyl]-1-(phenylmethyl)-4-piperidinyl]-2-hydroxy-4-oxo-2-butenoic acid, monohydrochloride |
| Anwendung: | Influenza PA endonuclease inhibitor |
| CAS | 174605-64-2 |
| MW: | 450.4 D |
ab 67,00 €
Baloxavir
Artikelnummer: Cay35125-100
Baloxavir is an active metabolite of baloxavir marboxil (Cay-33214). It inhibits influenza virus cap-dependent endonuclease (CEN) and CEN/RNA-dependent RNA polymerase (CEN/RdRp) activities in cell-free assays (IC50s = 2.5 and 1.6 nM, respectively). Baloxavir reduces viral titers in MDCK cells infected with...
| Schlagworte: | BXA, S-033447,... |
| Anwendung: | Baloxavir marboxil active metabolite |
| CAS | 1985605-59-1 |
| MW: | 483.5 D |
ab 44,00 €
