Zu "K19388" wurden 5 Artikel gefunden!
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Pimodivir
Artikelnummer: Cay29321-10
Pimodivir is an inhibitor of influenza virus polymerase basic protein 2 (PB2, KD = i = ~1.6 µM) and inhibits the activity of Axl and calcium/calmodulin-dependent protein kinase IIbeta (CaMKIIbeta) by greater than 50% in a panel of 65 human and rat kinases. Pimodivir decreases the replication of seven adamantine- and...
| Schlagworte: | JNJ 63623872, JNJ 872, VX 787,... |
| Anwendung: | Influenza virus PB2 inhibitor |
| CAS | 1629869-44-8 |
| MW: | 399.4 D |
ab 144,00 €
Pimodivir
Artikelnummer: TGM-T4377-100mg
Description: Pimodivir (VX-787), an influenza A virus polymerases inhibitor via oral, interacts with the viral PB2 subunit. Target: Influenza Virus. Smiles: OC(=O)[C@H]1C2CCC(CC2)[C@@H]1Nc1nc(ncc1F)-c1c[nH]c2ncc(F)cc12. References: Smee DF, et al. Activities of JNJ63623872 and oseltamivir against influenza A H1N1pdm...
| Schlagworte: | VX-787 |
| Anwendung: | Targets Influenza virus polymerase basic protein 2 (PB2) |
| CAS | 1629869-44-8 |
| MW: | 399.39 D |
ab 30,00 €
Pimodivir HCl
Artikelnummer: TGM-T4377L-25mg
Description: Pimodivir is an inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. The cell-based EC50 for VX-787 is 1.6 nM in a cytopathic effect (CPE) assay. VX-787 is active against a diverse panel of influenza A virus strains. Target:...
| Schlagworte: | Pimodivir hydrochloride hemihydrate, Pimodivir hydrochloride |
| Anwendung: | Targets Influenza virus polymerase basic protein 2 (PB2) |
| CAS | 1777721-70-6 |
| MW: | 444.86 D |
1.440,00 €
Polymerase basic protein 2 (PB2), recombinant Influenza A...
Artikelnummer: CSB-EP361051IFZ_A4_.1
Organism: Influenza A virus (strain A/Puerto Rico/8/1934 H1N1). Source: E.coli. Expression Region: 1-759aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MERIKELRNL MSQSRTREIL TKTTVDHMAI IKKYTSGRQE KNPALRMKWM MAMKYPITAD KRITEMIPER NEQGQTLWSK...
| Schlagworte: | Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3 |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | Influenza A virus |
| MW: | 93.6 kD |
ab 247,00 €
Polymerase basic protein 2 (PB2), recombinant Influenza A...
Artikelnummer: CSB-BP361051IFZ_A4_.1
Organism: Influenza A virus (strain A/Puerto Rico/8/1934 H1N1). Source: Baculovirus. Expression Region: 1-759aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MERIKELRNL MSQSRTREIL TKTTVDHMAI IKKYTSGRQE KNPALRMKWM MAMKYPITAD KRITEMIPER NEQGQTLWSK...
| Schlagworte: | Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3 |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | Influenza A virus |
| MW: | 92.9 kD |
ab 489,00 €
