Zu "K19261" wurden 28 Artikel gefunden!
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Sisunatovir
Artikelnummer: Cay42124-10
An RSV fusion inhibitor (IC50 = 0.9 nM), reduces RSV A2 replication in a plaque reduction assay in vitro (EC50 = 1.3 nM), decreases lung viral titers in a mouse model of RSV infection at 1, 10, or 50 mg/kg. Formulation: A solid. InChI:...
| Schlagworte: | RV521,... |
| Anwendung: | RSV fusion inhibitor |
| CAS | 1903763-82-5 |
| MW: | 446.44 D |
ab 163,00 €
respiratory syncytial virus B Fusion glycoprotein F0 (F),...
Artikelnummer: CSB-YP516611HXK.1
Organism: Human respiratory syncytial virus B (strain B1). Source: Yeast. Expression Region: 137-574aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: FLGFLLGVGS AIASGIAVSK VLHLEGEVNK IKNALLSTNK AVVSLSNGVS VLTSKVLDLK NYINNQLLPI VNQQSCRISN IETVIEFQQK NSRLLEINRE FSVNAGVTTP...
| Schlagworte: | F, Recombinant Human respiRatory syncytial virus B Fusion glycoprotein F0 (F), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | Human respiratory syncytial virus B |
| MW: | 50.1 kD |
ab 242,00 €
Sisunatovir
Artikelnummer: TGM-T24747-2mg
Description: RV521 is a highly effective fusion inhibitor. It designed to treat RSV disease by the target of a surface protein that mediates RSV binding to cellular receptors. Target: Others. Smiles: NCc1ccc2n(CCCC(F)(F)F)c(CN3C(=O)C4(CC4)c4ccc(F)cc34)nc2c1
| Schlagworte: | RV521, RV-521, RV 521, RV521 free base |
| Anwendung: | Targets Pneumoviridae fusion glycoprotein F0 (F) |
| CAS | 1903763-82-5 |
| MW: | 446.44 D |
ab 83,00 €
Clesrovimab
Artikelnummer: TGM-T77132-10mg
Description: Clesrovimab (MK1654) is an anti-respiratory syncytial virus protein F human monoclonal antibody for the prevention and treatment of respiratory syncytial virus infections. Target: Others. References: Qiu X, et al. Development of mRNA vaccines against respiratory syncytial virus (RSV). Cytokine Growth...
| Schlagworte: | MK-1654 |
| Anwendung: | Targets Pneumoviridae fusion glycoprotein F0 (F) |
| CAS | 2429913-18-6 |
ab 430,00 €
Palivizumab
Artikelnummer: TGM-T76907-100mg
Description: Palivizumab (MEDI 493) is a humanized RSV-specific monoclonal antibody that selectively inhibits epitopes at the F protein A antigenic site of RSV subtypes A and B for the prevention of respiratory syncytial virus infection (RSV). Target: RSV. References: Palivizumab, a humanized respiratory syncytial...
| Schlagworte: | MEDI 493, Synagis |
| Anwendung: | Targets Pneumoviridae fusion glycoprotein F0 (F) |
| CAS | 188039-54-5 |
ab 215,00 €
Sisunatovir hydrochloride
Artikelnummer: TGM-T9197-100mg
Description: Sisunatovir hydrochloride (RV521 HCl) is an orally available inhibitor of the RSV-F protein that has exhibited potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses in vitro (IC50 = 1.4 nM for RSV-A, IC50 = 1.0 nM for RSV-B). Target: RSV. Smiles:...
| Schlagworte: | Sisunatovir HCl, RV521 HCl |
| Anwendung: | Targets Pneumoviridae fusion glycoprotein F0 (F) |
| CAS | 1903763-83-6 |
| MW: | 482.9 D |
ab 49,00 €
Presatovir
Artikelnummer: TGM-TQ0085-100mg
Description: Presatovir (GS-5806) (GS-5806) is a novel, orally bioavailable RSV fusion inhibitor (mean EC50: 0.43 nM). Target: RSV. Smiles: Cc1cn2nc(cc2nc1N1CC[C@H](N)C1)[C@@H]1CCCCN1C(=O)c1cc(Cl)ccc1NS(C)(=O)=O. References: Samuel D, et al. GS-5806 inhibits pre- to postfusion conformational changes of the...
| Schlagworte: | GS-5806 |
| Anwendung: | Targets Pneumoviridae fusion glycoprotein F0 (F) |
| CAS | 1353625-73-6 |
| MW: | 532.06 D |
ab 55,00 €
Nirsevimab (YTE Mutant)
Artikelnummer: BPS-83759-1
Nirsevimab, also known as MEDI8897, is a recombinant neutralizing monoclonal antibody developed against human respiratory syncytial virus (RSV). It is an IgG1kappa antibody, that has a triple mutation in the Fc region designed to increase its serum half-life. The YTE (M252Y/S254T/T256E) mutation increases the...
| Schlagworte: | F, Fusion glycoprotein F0 |
| Anwendung: | Biochemical, cellular assays |
| Wirt: | Hamster |
| Spezies-Reaktivität: | human |
| CAS | 1989556-22-0 |
ab 1.500,00 €
Anti-RSV F (11A9), Epitope II, biotinylated
Artikelnummer: NOV-DA091BDL.100ug
Respiratory syncytial virus (RSV) is a highly contagious pathogen of the respiratory tract, primarily in infants and the elderly. A vaccine against RSV is currently not available, but is desired due to the high disease burden.RSV has two major surface glycoproteins (G and F) that play important roles in the initial...
| Schlagworte: | Anti-F, Biotinylated RSV F Antibody (11A9), Epitope II |
| Wirt: | Human |
| Spezies-Reaktivität: | Biotinylated RSV F Antibody (11A9), Epitope II |
ab 450,00 €
Anti-RSV Pre-F (3C12), Epitope Phi
Artikelnummer: NOV-DA101.100ug
Respiratory syncytial virus (RSV) is a highly contagious pathogen of the respiratory tract, primarily in infants and the elderly. A vaccine against RSV is currently not available, but is desired due to the high disease burden.RSV has two major surface glycoproteins (G and F) that play important roles in the initial...
| Schlagworte: | Anti-F, RSV Pre-F Antibody (3C12), Epitope Phi |
| Wirt: | Human |
| Spezies-Reaktivität: | RSV Pre-F Antibody (3C12), Epitope Phi |
ab 250,00 €
Anti-RSV F (4D5), Epitope I, biotinylated
Artikelnummer: NOV-DA102BDL.100ug
Respiratory syncytial virus (RSV) is a highly contagious pathogen of the respiratory tract, primarily in infants and the elderly. A vaccine against RSV is currently not available, but is desired due to the high disease burden.RSV has two major surface glycoproteins (G and F) that play important roles in the initial...
| Schlagworte: | Anti-F, Biotinylated RSV F Antibody (4D5), Epitope I |
| Wirt: | Human |
| Spezies-Reaktivität: | Biotinylated RSV F Antibody (4D5), Epitope I |
ab 495,00 €
Anti-RSV F (4B9), Epitope III
Artikelnummer: NOV-DA110.100ug
Respiratory syncytial virus (RSV) is a highly contagious pathogen of the respiratory tract, primarily in infants and the elderly. A vaccine against RSV is currently not available, but is desired due to the high disease burden.RSV has two major surface glycoproteins (G and F) that play important roles in the initial...
| Schlagworte: | Anti-F, RSV F Antibody (4B9), Epitope III |
| Wirt: | Human |
| Spezies-Reaktivität: | RSV F Antibody (4B9), Epitope III |
ab 328,00 €