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Zu "K18952" wurden 61 Artikel gefunden!
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Artikelnummer: E-AN301942L.100
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent...
| Schlagworte: | Anti-PRKCZ, Anti-nPKC-zeta, Anti-Protein kinase C zeta type, Recombinant PKC zeta Monoclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 304,00 €
Artikelnummer: NSJ-FY12835
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Pan-PKC antibody detects protein kinase C isoforms alpha, beta, and zeta, encoded by the PRKCA, PRKCB, and PRKCZ genes. PKC proteins are a family of serine/threonine kinases activated by...
| Schlagworte: | Anti-PRKCZ, Anti-nPKC-zeta, Anti-Protein kinase C zeta type, Pan-PKC Antibody / PRKCA/PRKCB/PRKCZ |
| Anwendung: | WB, IHC, ICC, IF, IP, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Artikelnummer: Cay17482-1
The atypical protein kinase C isoform, PKCzeta, is critical for mediating mitogenic signal transduction, cell survival, and some of the physiological actions of insulin. PKCzeta pseudosubstrate inhibitor is a synthetic peptide that corresponds to a pseudosubstrate domain of this PKC isoform. It selectively,...
| Schlagworte: | Protein Kinase Czeta Pseudosubstrate Inhibitor,... |
| Anwendung: | PKCzeta inhibitor |
| CAS | 799764-07-1 |
| MW: | 1718 D |
ab 148,00 €
Artikelnummer: ARG51788.100
Protein function: Calcium- and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory...
| Schlagworte: | Anti-phospho-PKC2, Anti-phospho-PRKCZ, Anti-phospho-nPKC-zeta, EC=2.7.11.13, Anti-phospho-Protein kinase C zeta type |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
ab 471,00 €
Artikelnummer: ARG55524.100
Protein function: Calcium- and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory...
| Schlagworte: | Anti-PKC2, Anti-PRKCZ, Anti-nPKC-zeta, EC=2.7.11.13, Anti-Protein kinase C zeta type |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Artikelnummer: E-AB-32609.120
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor...
| Schlagworte: | Anti-PKC2, Anti-PRKCZ, Anti-nPKC-zeta, EC=2.7.11.13, Anti-Protein kinase C zeta type, PKC zeta Polyclonal Antibody |
| Anwendung: | WB, IHC (paraffin), IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 89,00 €
Artikelnummer: Cay25556-1
PKC-9 is an inhibitor of PKCzeta that is 8,000-, 20,671-, 711-, 918-, 1,895-, 12,424-, 10-, and 1,218-fold selective for PKCzeta over PKCalpha, PKCbetaII, PKCgamma, PKCdelta, PKCepsilon, PKCeta, PKCiota, and PKCtheta, respectively. It also inhibits 27 additional kinases in a panel of 37 kinases when used at a...
| Schlagworte: | 4-[3-[7-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl]-benzenamine |
| Anwendung: | PKCzeta inhibitor |
| CAS | 1132609-87-0 |
| MW: | 423.5 D |
ab 133,00 €
Artikelnummer: ARG57610.100
Protein function: Calcium- and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory...
| Schlagworte: | Anti-phospho-PKC2, Anti-phospho-PRKCZ, Anti-phospho-nPKC-zeta, EC=2.7.11.13, Anti-phospho-Protein kinase C zeta type |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Artikelnummer: Cay28463-1
CRT0066854 is an inhibitor of PKCiota and PKCzeta (IC50s = 132 and 639 nM, respectively). It also inhibits the Rho-associated kinase II (ROCK2) kinase domain (IC50 = 620 nM). It is selective for these atypical PKCs and ROCK2 over typical PKCs and 98 other kinases in a panel at 1 µM. CRT0066854 decreases...
| Schlagworte: | (2S)-3-phenyl-N1-[5,6,7,8-tetrahydro-2-(4-pyridinyl)[1]benzothieno[2,3-d]pyrimidin-4-yl]-1,2-propanediamine |
| Anwendung: | PKCiota / PKCzeta inhibitor |
| CAS | 1438881-19-6 |
| MW: | 415.6 D |
ab 76,00 €
Artikelnummer: Cay34445-1
Myr-ZIP is a cell-permeable inhibitor of the constitutively active protein kinase C (PKC) isoform PKMzeta (Ki = 0.076-2.11 µM). It also inhibits PKCalpha when used at a concentration of 10 µM. Myr-ZIP (5 µM) prevents PKC translocation to the plasma membrane induced by ionomycin (Cay-10004974, Cay-11932) in HEK293...
| Schlagworte: | Myristoylated Zeta-Pseudosubstrate Inhibitory Peptide, Myristoylated-ZIP,... |
| Anwendung: | PKMzeta inhibitor |
| MW: | 1928.4 D |
ab 281,00 €
Artikelnummer: ATA-HPA021851.100
Protein function: Calcium- and diacylglycerol-independent serine/threonine- protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory...
| Schlagworte: | Anti-PKC2, Anti-PRKCZ, Anti-nPKC-zeta, Anti-Protein kinase C zeta type |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 330,00 €
Artikelnummer: ELK-ELK1680.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PKCz. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PKCz. Next,...
| Schlagworte: | PKC2, PRKCZ, nPKC-zeta, Protein kinase C zeta type |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €