Zu "K18671" wurden 22 Artikel gefunden!
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Chidamide
Artikelnummer: Cay13686-1
Chidamide is an inhibitor of histone deacetylases (HDACs, IC50s = 0.095, 0.160, 0.067, 0.733, 0.078, and 0.432 µM for HDAC1-3, 8, 10, and 11, respectively). It is selective for these HDACs over HDAC4-7 and 9 (IC50s = >30 µM for all). Chidamide also inhibits nicotinamide phosphoribosyltransferase (Nampt, IC50 = 2.1...
| Schlagworte: | CS 055, HBI 8000, Tucidinostat, N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-benzamide |
| Anwendung: | HDAC inhibitor |
| CAS | 1616493-44-7 |
| MW: | 390.4 D |
ab 50,00 €
KD 5170
Artikelnummer: Cay13214-1
KD 5170 is a mercaptoketone-based inhibitor of class I and II histone deacetylases (HDACs, IC50s = 20, 2,060, 75, 26, 950, 14, 85, 2,500, 150, and 18 nM for HDAC1-10, respectively). It exhibits broad spectrum antitumor activity in vitro and in vivo. KD 5170 increases the acetylation of histones and activates...
| Schlagworte: | ethanethioic acid S-[2-[6-[[[4-[3-(dimethylamino)propoxy]phenyl]sulfonyl]amino]-3-pyridinyl]-2-oxoethyl] ester |
| Anwendung: | HDAC inhibitor |
| CAS | 940943-37-3 |
| MW: | 451.6 D |
ab 46,00 €
HDAC-10 (FLAG), active human recombinant protein
Artikelnummer: BPS-50060
Active human HDAC10 (a.a. 2-631) (GenBank Accession No. NM_032019) with N-terminal FLAG-tag, MW= 67 kDa, expressed in Sf9 cells via a baculovirus expression system
| Schlagworte: | HD10, HDAC10, Histone deacetylase 10, Polyamine deacetylase HDAC10, |
| Anwendung: | Enzyme kinetics, inhibitor screening, profiling |
| MW: | 67 kD |
606,00 €
Anti-HDAC10
Artikelnummer: 600-401-J75
Anti-HDAC10 was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with human based on 100% sequence homology. Cross-reactivity with HDAC10 from other sources has not been determined. HDAC10 is located in the nucleus and cytoplasm,...
| Schlagworte: | Anti-HD10, Anti-HDAC10, EC=3.5.1.98, Anti-Histone deacetylase 10 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
684,00 €
Anti-HDAC10
Artikelnummer: ARG41799.100
Protein function: Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine (PubMed:28516954). Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine...
| Schlagworte: | Anti-HD10, Anti-HDAC10, Anti-Histone deacetylase 10, Anti-Polyamine deacetylase HDAC10 |
| Anwendung: | ICC, IF, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
624,00 €
Anti-HDAC10
Artikelnummer: G-CAB6184.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €
Anti-HDAC10
Artikelnummer: ATA-HPA056514.100
Protein function: Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine (PubMed:28516954). Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine...
| Schlagworte: | Anti-HD10, Anti-HDAC10, Anti-Histone deacetylase 10, Anti-Polyamine deacetylase HDAC10 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
Anti-HDAC10
Artikelnummer: E-AB-92707.120
The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and...
| Schlagworte: | HD10, HDAC10, Histone deacetylase 10, Polyamine deacetylase HDAC10, HDAC10 Polyclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Anti-Histone deacetylase 10
Artikelnummer: ELK-ES2519.100
The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and...
| Schlagworte: | Anti-HD10, Anti-HDAC10, Anti-Histone deacetylase 10, Anti-Polyamine deacetylase HDAC10, Histone deacetylase 10 rabbit pAb |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 169,00 €
Anti-HDAC10
Artikelnummer: 600-401-J76
Anti-HDAC10 was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with human based on 100% sequence homology. Cross-reactivity with HDAC10 from other sources has not been determined. HDAC10 is located in the nucleus and cytoplasm,...
| Schlagworte: | Anti-HD10, Anti-HDAC10, EC=3.5.1.98, Anti-Histone deacetylase 10 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
684,00 €
Anti-HDAC10
Artikelnummer: 600-401-J77
Anti-HDAC10 was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with human based on 100% sequence homology. Cross-reactivity with HDAC10 from other sources has not been determined. HDAC10 is located in the nucleus and cytoplasm,...
| Schlagworte: | Anti-HD10, Anti-HDAC10, EC=3.5.1.98, Anti-Histone deacetylase 10 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
684,00 €
Anti-HDAC10
Artikelnummer: 600-401-J78
Anti-HDAC10 was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with human based on 100% sequence homology. Cross-reactivity with HDAC10 from other sources has not been determined. HDAC10 is located in the nucleus and cytoplasm,...
| Schlagworte: | Anti-HD10, Anti-HDAC10, EC=3.5.1.98, Anti-Histone deacetylase 10 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
684,00 €