Zu "K18529" wurden 18 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
APS-2-79 (hydrochloride)
Artikelnummer: Cay22137-5
APS-2-79 is an inhibitor of MAPK signaling dependent on kinase suppressor of Ras (KSR). It inhibits ATPbiotin binding to KSR2 in KSR2-MEK1 complexes (IC50 = 120 nM), stabilizes KSR2 in an inactive state, and reduces interactions between B-RAF and KSR2-MEK1 complexes. APS-2-79 (5 µM) inhibits KSR-stimulated...
| Schlagworte: | 6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)-4-quinazolinamine, monohydrochloride |
| Anwendung: | KSR-dependent MAPK signaling modulator |
| CAS | 2002381-31-7 |
| MW: | 423.9 D |
ab 44,00 €
Human KSR2 ELISA Kit
Artikelnummer: G-HUFI01627.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Mouse KSR2 ELISA Kit
Artikelnummer: G-MOFI00490.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
694,00 €
Anti-KSR2
Artikelnummer: ATA-HPA035536.100
Protein function: Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Acts as MAP2K1/MEK1-dependent allosteric activator of BRAF, upon binding to MAP2K1/MEK1, dimerizes with BRAF and...
| Schlagworte: | Anti-KSR2, Anti-hKSR2, Anti-Kinase suppressor of Ras 2 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
Anti-Ksr2
Artikelnummer: ELK-ES5584.100
domain:The protein kinase domain is predicted to be catalytically inactive.,function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting...
| Schlagworte: | Anti-hKSR2, Anti-Kinase suppressor of Ras 2, Ksr2 rabbit pAb |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 169,00 €
Anti-KSR2, CT (KSR2, Kinase suppressor of Ras 2) (Azide...
Artikelnummer: 037646-APC.200
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Applications: Suitable for use in Western Blot,...
| Schlagworte: | Anti-KSR2, Anti-hKSR2, EC=2.7.11.1, Anti-Kinase suppressor of Ras 2 |
| Anwendung: | FLISA, FC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
993,00 €
Anti-KSR2, CT (KSR2, Kinase suppressor of Ras 2) (Azide...
Artikelnummer: 037646-Biotin.200
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Applications: Suitable for use in Western Blot,...
| Schlagworte: | Anti-KSR2, Anti-hKSR2, EC=2.7.11.1, Anti-Kinase suppressor of Ras 2 |
| Anwendung: | ELISA, FC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
993,00 €
Anti-KSR2, CT (KSR2, Kinase suppressor of Ras 2) (Azide...
Artikelnummer: 037646-FITC.200
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Applications: Suitable for use in Western Blot,...
| Schlagworte: | Anti-KSR2, Anti-hKSR2, EC=2.7.11.1, Anti-Kinase suppressor of Ras 2 |
| Anwendung: | FLISA, FC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
993,00 €
Anti-KSR2, CT (KSR2, Kinase suppressor of Ras 2) (Azide...
Artikelnummer: 037646-HRP.200
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Applications: Suitable for use in Western Blot,...
| Schlagworte: | Anti-KSR2, Anti-hKSR2, EC=2.7.11.1, Anti-Kinase suppressor of Ras 2 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
993,00 €
Anti-KSR2, CT (KSR2, Kinase suppressor of Ras 2)
Artikelnummer: 037646.200
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Applications: Suitable for use in Western Blot,...
| Schlagworte: | Anti-KSR2, Anti-hKSR2, EC=2.7.11.1, Anti-Kinase suppressor of Ras 2 |
| Anwendung: | ELISA, FC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
728,00 €
Anti-Ksr2, CT (Ksr2, Kinase suppressor of Ras 2) (Azide...
Artikelnummer: 037647-APC.200
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production (By similarity). Applications: Suitable for use in...
| Schlagworte: | Anti-Ksr2, EC=2.7.11.1, Anti-Kinase suppressor of Ras 2 |
| Anwendung: | FLISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
993,00 €
Anti-Ksr2, CT (Ksr2, Kinase suppressor of Ras 2) (Azide...
Artikelnummer: 037647-Biotin.200
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production (By similarity). Applications: Suitable for use in...
| Schlagworte: | Anti-Ksr2, EC=2.7.11.1, Anti-Kinase suppressor of Ras 2 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
993,00 €