Zu "K18052" wurden 72 Artikel gefunden!
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Sotrastaurin
Artikelnummer: Cay16726-1
Sotrastaurin is a protein kinase C (PKC) inhibitor that displays immunosuppressive activity, blocking T cell activation through the disruption of downstream NF-kappaB signaling. In cell-free assays, sotrastaurin was reported to inhibit PKCalpha, betaI, delta, epsilon, eta, and theta with Ki values of 0.95, 0.64,...
| Schlagworte: | AEB071, 3-(1H-indol-3-yl)-4-[2-(4-methyl-1-piperazinyl)-4-quinazolinyl]-1H-pyrrole-2,5-dione |
| Anwendung: | PKC inhibitor, immunosuppressor |
| CAS | 425637-18-9 |
| MW: | 438.5 D |
ab 76,00 €
VTX-27
Artikelnummer: SYN-1206-M001
Soluble in DMSO. VTX-27 is a potent and selective inhibitor of the PKCtheta enzyme, with over 1000-fold against classical isoforms and over 10000-fold against atypical isoforms. Target: PKC theta
| Schlagworte: | VTX27 |
| Anwendung: | PKC theta inhibitor |
| CAS | 1321924-70-2 |
| MW: | 418,9 D |
ab 339,00 €
Anti-phospho-PKC theta (Ser695)
Artikelnummer: ARG51669.100
Protein function: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that mediates non- redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple...
| Schlagworte: | Anti-phospho-PRKCT, Anti-phospho-PRKCQ, Anti-phospho-nPKC-theta, EC=2.7.11.13, Anti-phospho-Protein kinase C theta type |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-phospho-PKC theta (Ser676)
Artikelnummer: ARG51775.100
Protein function: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that mediates non- redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple...
| Schlagworte: | Anti-phospho-PRKCQ, Anti-phospho-PRKCT, Anti-phospho-nPKC-theta, EC=2.7.11.13, Anti-phospho-Protein kinase C theta type |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-PRKCQ
Artikelnummer: A304-232A
Protein function: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that mediates non- redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple...
| Schlagworte: | Anti-PRKCQ, Anti-PRKCT, Anti-nPKC-theta, EC=2.7.11.13, Anti-Protein kinase C theta type |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-PRKCQ
Artikelnummer: A304-233A
Protein function: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that mediates non- redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple...
| Schlagworte: | Anti-PRKCQ, Anti-PRKCT, Anti-nPKC-theta, EC=2.7.11.13, Anti-Protein kinase C theta type |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
PKCtheta Pseudosubstrate Inhibitor
Artikelnummer: Cay17483-1
PKCtheta pseudosubstrate inhibitor is a synthetic peptide that corresponds to amino acid residues of the pseudosubstrate domain of protein kinase Ctheta (PKCtheta). It selectively, reversibly, and substrate-competitively inhibits PKCtheta activity and, thus, is used to delineate the signaling functions of PKCtheta,...
| Schlagworte: | Protein Kinase Ctheta Pseudosubstrate Inhibitor,... |
| Anwendung: | PRKCQ inhibitor |
| MW: | 2173.6 D |
ab 144,00 €
LXS-196
Artikelnummer: LKT-L943721.1
Selective inhibitor of protein kinase C (PKC).
| Schlagworte: | LXS 196, LXS196, NVP-LXS196 |
| Anwendung: | Selective PKC inhibitor |
| CAS | 1874276-76-2 |
| MW: | 472.48 D |
ab 123,00 €
LXS-196
Artikelnummer: Cay31455-1
LXS-196 is a PKC inhibitor (IC50s = 1.9 and 0.4 nM for PKCalpha and PKCtheta, respectively). It is selective for PKCalpha and PKCtheta over GSK3beta (IC50 = 3,100 nM). It inhibits proliferation of TMD8 B cell lymphoma and 92.1 uveal melanoma cells (IC50s = 900 and 184 nM, respectively) but not SK-MEL-28 skin...
| Schlagworte: | 3-amino-N-[3-(4-amino-4-methyl-1-piperidinyl)-2-pyridinyl]-6-[3-(trifluoromethyl)-2-pyridinyl]-2-pyrazinecarboxamide |
| Anwendung: | PKC inhibitor |
| CAS | 1874276-76-2 |
| MW: | 472.5 D |
ab 78,00 €
Anti-PKC theta / PRKCQ
Artikelnummer: NSJ-RQ5754
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Protein kinase C theta is an enzyme that in humans is encoded by the PRKCQ gene. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members...
| Schlagworte: | Anti-PRKCQ, Anti-PRKCT, Anti-nPKC-theta, Anti-Protein kinase C theta type, PKC theta Antibody / PRKCQ |
| Anwendung: | WB, IHC (paraffin), Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-PRKCQ
Artikelnummer: ATA-HPA065279.100
Protein function: Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that mediates non-redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple...
| Schlagworte: | Anti-PRKCT, Anti-PRKCQ, Anti-nPKC-theta, Anti-Protein kinase C theta type |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-PRKCQ
Artikelnummer: ATA-HPA073098.100
Protein function: Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that mediates non-redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple...
| Schlagworte: | Anti-PRKCT, Anti-PRKCQ, Anti-nPKC-theta, Anti-Protein kinase C theta type |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €