Zu "K17726" wurden 19 Artikel gefunden!
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TP-0472993
Artikelnummer: Cay39757-10
TP-0472993 is an inhibitor of the cytochrome P450 (CYP) isoforms CYP4A11 and CYP4F2 (IC50s = 140 and 40 nM, respectively). It is selective for CYP4A11 and CYP4F2 over a panel of eight additional CYPs at 10 µM. TP-0472993 inhibits 20-HETE (Cay-90030) production in rat renal microsomes (IC50 = 347 nM). In vivo,...
| Schlagworte: | 1-[4-[[[6-(1H-pyrazol-3-yl)-3-pyridinyl]oxy]methyl]-1-piperidinyl]-ethanone |
| Anwendung: | CYP4A11 / CYP4F2 inhibitor |
| CAS | 2126874-77-7 |
| MW: | 300.4 D |
ab 137,00 €
Anti-CYP4F2
Artikelnummer: CSB-PA001980.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYPIVF2, Anti-20-HETE synthase, Anti-Cytochrome P450 4F2, Anti-Cytochrome P450-LTB-omega, Anti-Arachidonic acid... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 106,00 €
Anti-CYP4F2
Artikelnummer: CSB-PA916473.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-CYPIVF2, Anti-20-HETE synthase, Anti-Cytochrome P450 4F2, Anti-Cytochrome P450-LTB-omega, Anti-Arachidonic acid... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
18-hydroxy Oleoyl Leucine-d7
Artikelnummer: Cay9004331-1
18-hydroxy Oleoyl leucine-d7 is intended for use as an internal standard for the quantification of 18-hydroxy oleoyl leucine by GC- or LC-MS. 18-hydroxy oleoyl leucine is a omega-hydroxy metabolite of the N-acyl amide mitochondrial uncoupling agent N-oleoyl leucine (Cay-20064). It is formed from N-oleoyl leucine by...
| Anwendung: | GC-MS, LC-MS internal standard, quantification, CYP4F2 N-oleoyl leucine product |
| MW: | 418.7 D |
ab 66,00 €
Oleic Acid-hydroxy Oleoyl Leucine-d7
Artikelnummer: Cay9004332-1
Oleic acid-hydroxy oleoyl leucine-d7 is intended for use as an internal standard for the quantification of oleic acid-hydroxy oleoyl leucine by GC- or LC-MS. Oleic acid-hydroxy oleoyl leucine is a very long-chain fatty acid composed of oleic acid (Cay-90260, Cay-24659) connected to hydroxy oleoyl leucine.Synonyms:...
| Schlagworte: | C18:1-hydroxy Oleoyl Leucine-d7, OAHOL-d7 |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, VLC fatty acid N-hydroxy-acyl amino acid ester |
| MW: | 683.1 D |
ab 66,00 €
Human CYP4F2 (Cytochrome P450 4F2) ELISA Kit
Artikelnummer: ELK-ELK7582.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CYP4F2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CYP4F2....
| Schlagworte: | CYPIVF2, 20-HETE synthase, Cytochrome P450 4F2, Cytochrome P450-LTB-omega, Arachidonic acid omega-hydroxylase,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
20-HEPE
Artikelnummer: Cay19322-25
20-HEPE is a metabolite of eicosapentaenoic acid (EPA, Cay-90110, Cay-21908, Cay-90110.1) that is formed via omega-oxidation of EPA by cytochrome P450 (CYP) omega-oxidases, including human CYP4F3B. It activates peroxisome proliferator-activated receptor alpha (PPARalpha) in COS-7 cells expressing a luciferase...
| Schlagworte: | 20-hydroxy-5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid |
| Anwendung: | EPA metabolite |
| CAS | 116477-57-7 |
| MW: | 318.5 D |
ab 328,00 €
22-HDHA
Artikelnummer: Cay19321-25
22-HDHA is an oxidation product of docosahexaenoic acid (DHA, Cay-90310). In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in...
| Schlagworte: | 22-hydroxy Docosahexaenoic Acid, 22-OH DHA, 22-hydroxy-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid |
| Anwendung: | DHA oxidation product |
| CAS | 90780-46-4 |
| MW: | 344.5 D |
ab 391,00 €
Anti-CYP4F2
Artikelnummer: ATA-HPA014048.100
Protein function: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, eicosanoids and vitamins (PubMed:18577768, PubMed:10833273, PubMed:10660572, PubMed:11997390, PubMed:17341693, PubMed:18574070). Mechanistically, uses molecular oxygen inserting one...
| Schlagworte: | Anti-CYPIVF2, Anti-20-HETE synthase, Anti-Cytochrome P450 4F2, Anti-Cytochrome P450-LTB-omega, Anti-Arachidonic acid... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
Anti-CYP4F2
Artikelnummer: ATA-HPA058960.100
Protein function: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, eicosanoids and vitamins (PubMed:18577768, PubMed:10833273, PubMed:10660572, PubMed:11997390, PubMed:17341693, PubMed:18574070). Mechanistically, uses molecular oxygen inserting one...
| Schlagworte: | Anti-CYPIVF2, Anti-20-HETE synthase, Anti-Cytochrome P450 4F2, Anti-Cytochrome P450-LTB-omega, Anti-Arachidonic acid... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
Anti-CYP4F2
Artikelnummer: E-AB-90083.120
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the...
| Schlagworte: | CYPIVF2, 20-HETE synthase, Cytochrome P450 4F2, Cytochrome P450-LTB-omega, Arachidonic acid omega-hydroxylase,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 198,00 €
Anti-CP4F3
Artikelnummer: ELK-ES9129.100
This gene, CYP4F3, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts...
| Schlagworte: | Anti-LTB4H, Anti-CYPIVF3, Anti-20-HETE synthase, Anti-Cytochrome P450 4F3, Anti-Cytochrome P450-LTB-omega,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse, |
ab 169,00 €