Zu "K17726" wurden 27 Artikel gefunden!
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TP0472993
Artikelnummer: TGM-T67916-100mg
Description: CYP4A11/CYP4F2-IN-2 is a potent and orally active dual inhibitor of cytochrome P450 (CYP) 4A11 and CYP4F2, with IC50 values of 140 nM and 40 nM, respectively. Extractable from liver and kidney, CYP4A11/CYP4F2-IN-2 has the potential to treat kidney diseases. Target: P450. Smiles:...
| Anwendung: | CYP4A11 / CYP4F2 inhibitor |
| CAS | 2126874-77-7 |
| MW: | 300.36 D |
ab 45,00 €
TP-0472993
Artikelnummer: Cay39757-10
TP-0472993 is an inhibitor of the cytochrome P450 (CYP) isoforms CYP4A11 and CYP4F2 (IC50s = 140 and 40 nM, respectively). It is selective for CYP4A11 and CYP4F2 over a panel of eight additional CYPs at 10 µM. TP-0472993 inhibits 20-HETE (Cay-90030) production in rat renal microsomes (IC50 = 347 nM). In vivo,...
| Schlagworte: | 1-[4-[[[6-(1H-pyrazol-3-yl)-3-pyridinyl]oxy]methyl]-1-piperidinyl]-ethanone |
| Anwendung: | CYP4A11 / CYP4F2 inhibitor |
| CAS | 2126874-77-7 |
| MW: | 300.4 D |
ab 140,00 €
TS-011
Artikelnummer: TGM-T13215-10mg
Description: N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide (TS-011) is a selective 20-Hydroxyeicosatetraenoic acid synthesis inhibitor. Target: Others. Smiles: O\N=C\Nc1ccc(N2CCOCC2)c(Cl)c1. References: Marumo T, et al. The inhibitor of 20-HETE synthesis, TS-011, improves cerebral microcirculatory...
| Schlagworte: | TS-011 |
| Anwendung: | 20-HETE synthesis inhibitor |
| CAS | 339071-18-0 |
| MW: | 255.7 D |
ab 106,00 €
20-HEPE
Artikelnummer: Cay19322-25
20-HEPE is a metabolite of eicosapentaenoic acid (EPA, Cay-90110, Cay-21908, Cay-90110.1) that is formed via omega-oxidation of EPA by cytochrome P450 (CYP) omega-oxidases, including human CYP4F3B. It activates peroxisome proliferator-activated receptor alpha (PPARalpha) in COS-7 cells expressing a luciferase...
| Schlagworte: | 20-hydroxy-5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid |
| Anwendung: | EPA metabolite |
| CAS | 116477-57-7 |
| MW: | 318.5 D |
ab 356,00 €
Anti-CYP4F2
Artikelnummer: CSB-PA001980.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYPIVF2, Anti-20-HETE synthase, Anti-Cytochrome P450 4F2, Anti-Cytochrome P450-LTB-omega, Anti-Arachidonic acid... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
Anti-CYP4F2
Artikelnummer: CSB-PA916473.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-CYPIVF2, Anti-20-HETE synthase, Anti-Cytochrome P450 4F2, Anti-Cytochrome P450-LTB-omega, Anti-Arachidonic acid... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
22-HDHA
Artikelnummer: Cay19321-25
22-HDHA is an oxidation product of docosahexaenoic acid (DHA, Cay-90310). In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in...
| Schlagworte: | 22-hydroxy Docosahexaenoic Acid, 22-OH DHA, 22-hydroxy-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid |
| Anwendung: | DHA oxidation product |
| CAS | 90780-46-4 |
| MW: | 344.5 D |
ab 400,00 €
Anti-CYP4F2
Artikelnummer: ATA-HPA014048.100
Protein function: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, eicosanoids and vitamins (PubMed:18577768, PubMed:10833273, PubMed:10660572, PubMed:11997390, PubMed:17341693, PubMed:18574070). Mechanistically, uses molecular oxygen inserting one...
| Schlagworte: | Anti-CYPIVF2, Anti-20-HETE synthase, Anti-Cytochrome P450 4F2, Anti-Cytochrome P450-LTB-omega, Anti-Arachidonic acid... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-CYP4F2
Artikelnummer: ATA-HPA058960.100
Protein function: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, eicosanoids and vitamins (PubMed:18577768, PubMed:10833273, PubMed:10660572, PubMed:11997390, PubMed:17341693, PubMed:18574070). Mechanistically, uses molecular oxygen inserting one...
| Schlagworte: | Anti-CYPIVF2, Anti-20-HETE synthase, Anti-Cytochrome P450 4F2, Anti-Cytochrome P450-LTB-omega, Anti-Arachidonic acid... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
TS-011
Artikelnummer: Cay9002862-100
TS-011 is an inhibitor of 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis. It inhibits 20-HETE synthesis in human and rat renal microsomes (IC50s = 8.42 and 9.19 nM, respectively), as well as by the cytochrome P450 (CYP) isoforms CYP4F2, CYP4F3A, CYP4F3B, and CYP4A11 in cell-free assays (IC50s = 30.4, 42.6,...
| Schlagworte: | N-[3-chloro-4-(4-morpholinyl)phenyl]-N'-hydroxy-methanimidamide |
| Anwendung: | 20-HETE synthesis inhibitor |
| CAS | 339071-18-0 |
| MW: | 255.7 D |
ab 153,00 €
Human CYP4F2 (Cytochrome P450 4F2) ELISA Kit
Artikelnummer: ELK-ELK7582.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CYP4F2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CYP4F2....
| Schlagworte: | CYPIVF2, 20-HETE synthase, Cytochrome P450 4F2, Cytochrome P450-LTB-omega, Arachidonic acid omega-hydroxylase,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
18-hydroxy Oleoyl Leucine-d7
Artikelnummer: Cay9004331-1
18-hydroxy Oleoyl leucine-d7 is intended for use as an internal standard for the quantification of 18-hydroxy oleoyl leucine by GC- or LC-MS. 18-hydroxy oleoyl leucine is a omega-hydroxy metabolite of the N-acyl amide mitochondrial uncoupling agent N-oleoyl leucine (Cay-20064). It is formed from N-oleoyl leucine by...
| Anwendung: | GC-MS, LC-MS internal standard, quantification, CYP4F2 N-oleoyl leucine product |
| MW: | 418.7 D |
ab 67,00 €