Zu "K17721" wurden 48 Artikel gefunden!
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NEU
Anti-Recombinant CYP2C19, clone C112575
Artikelnummer: E-AN302955L.100
Protein function: A cytochrome P450 monooxygenase involved in the metabolism of polyunsaturated fatty acids (PUFA) (PubMed:18577768, PubMed:19965576, PubMed:20972997). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons...
| Schlagworte: | Anti-CYP2C19, Anti-CYPIIC19, Anti-CYPIIC17, Anti-Cytochrome P450-11A, Anti-Cytochrome P450-254C, Anti-Cytochrome P450... |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
Anti-CYP2C19 (recombinant antibody)
Artikelnummer: ABS-RN-14895.100
Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide. Identity-Mouse (%): 68%. Homologies: Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 79%, Pig - 80%, Cynomolgus monkey - 91%. IHC Verification: succeed. WB Verification: -. IP...
| Schlagworte: | Anti-CYP2C19, Anti-CYPIIC17, Anti-CYPIIC19, Anti-Cytochrome P450-11A, Anti-Cytochrome P450 2C19, Anti-Cytochrome... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Anti-CYP2C19
Artikelnummer: ABS-KC-44894.100
Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide. Identity-Mouse (%): 68%. Homologies: Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 79%, Pig - 80%, Cynomolgus monkey - 91%. IHC Verification: succeed. WB Verification: -. IP...
| Schlagworte: | Anti-CYP2C19, Anti-CYPIIC17, Anti-CYPIIC19, Anti-Cytochrome P450-11A, Anti-Cytochrome P450 2C19, Anti-Cytochrome... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
5-hydroxy Omeprazole
Artikelnummer: Cay10009028-500
5-hydroxy Omeprazole is a metabolite of the H+/K+-ATPase inhibitor omeprazole (Cay-14880). It is formed from omeprazole by the cytochrome P450 (CYP) isoform CYP2C19.Formal Name: 4-methoxy-6-[[(6-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-3-pyridinemethanol. CAS Number: 92340-57-3. Synonyms: 5-hydroxy...
| Schlagworte: | 4-methoxy-6-[[(6-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-3-pyridinemethanol |
| Anwendung: | Omeprazole metabolite |
| CAS | 92340-57-3 |
| MW: | 361.4 D |
ab 468,00 €
(±)4-Hydroxymephenytoin
Artikelnummer: Cay16124-5
(±)4-Hydroxymephenytoin is a metabolite of (R)-mephenytoin (Cay-25891) and (S)-mephenytoin (Cay-11913). It is formed from (R)- and (S)-mephenytoin by the cytochrome P450 (CYP) isoform CYP2C19 in the liver.Formal Name: 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione. CAS Number: 61837-65-8. Molecular...
| Schlagworte: | 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione |
| Anwendung: | (S)-mephenytoin metabolite |
| CAS | 61837-65-8 |
| MW: | 234.3 D |
ab 164,00 €
(±)-N-3-Benzylnirvanol
Artikelnummer: Cay27298-10
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (-)-N-3-benzylnirvanol. (+)-N-3-benzylnirvanol and (-)-N-3-benzylnirvanol are inhibitors of the cytochrome P450 (CYP) isoform CYP2C19 (Kis = 0.25 and 5.3 µM, respectively). (±)-N-3-Benzylnirvanol (20 mg/kg, i.p.) lowers plasma levels of...
| Schlagworte: | 5-ethyl-5-phenyl-3-(phenylmethyl)-2,4-imidazolidinedione |
| Anwendung: | CYP2C19 inhibitor |
| CAS | 93879-40-4 |
| MW: | 294.4 D |
ab 58,00 €
Clopidogrel Carboxylic Acid (hydrochloride)
Artikelnummer: Cay17871-1
Clopidogrel carboxylic acid is an inactive metabolite of (±)-clopidogrel (Cay-13657) and (S)-(+)-clopidogrel (Cay-21002). It is formed from (±)-clopidogrel and (S)-(+)-clopidogrel by carboxylesterase 1 (CES1).Formal Name: alphaS-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, monohydrochloride....
| Schlagworte: | SR26334, alphaS-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, monohydrochloride |
| Anwendung: | Clopidogrel metabolite, reference standard |
| CAS | 144750-42-5 |
| MW: | 344.3 D |
ab 76,00 €
3'-O-Methylfluorescein
Artikelnummer: CDX-M0098-M005
Light red to brown powder. Soluble in DMSO. Used in fluorimetric studies. Fluorescent probe. Selective fluorometric substrate for CYP2C19 and CYP1A1. Reaction product of the substrate 3-O-methylfluorescein phosphate (OMFP) is hydrolyzed by phosphatases to yield O-methylfluorescein (OMF) that is detected at a 485nm...
| Schlagworte: | Methylfluorescein |
| Anwendung: | Fluorescent probe, CYP2C19 and CYP1A1 selective fluorometric substrate |
| CAS | 70672-05-8 |
| MW: | 346,33 D |
ab 129,00 €
Voriconazole N-oxide
Artikelnummer: Cay28047-5
Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole (Cay-15633). It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19.Formal Name:...
| Schlagworte: | UK 121265,... |
| Anwendung: | Major voriconazole metabolite |
| CAS | 618109-05-0 |
| MW: | 365.3 D |
ab 251,00 €
Human CYP2C19 / Cytochrome P450 2C19 ELISA Kit
Artikelnummer: G-HUFI01988.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Stiripentol
Artikelnummer: Cay17781-5
Stiripentol is a third-generation antiepileptic compound. It is a positive allosteric modulator of GABAA receptors, potentiating GABA-mediated activation to a greater extent in receptors expressing alpha3 subunits and to a lower extent in those containing beta1 or epsilon subunits. It also inhibits GABA reuptake in...
| Schlagworte: | BCX 2600, 1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol |
| Anwendung: | Synaptosomal GABA uptake inhibitor, CYP3A4 / CYP1A2 / CYP2C19 inhibitor |
| CAS | 49763-96-4 |
| MW: | 234.3 D |
ab 105,00 €
Pantoprazole Sulfide
Artikelnummer: Cay22251-10
Pantoprazole sulfide is a metabolite of the gastric H+/K+ ATPase pump inhibitor pantoprazole (Cay-21345). Pantoprazole is metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4 to form pantoprazole sulfide.Formal Name: 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole. CAS...
| Schlagworte: | Pantoprazole thioether, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole |
| Anwendung: | Pantoprazole metabolite |
| CAS | 102625-64-9 |
| MW: | 367.4 D |
ab 51,00 €