Zu "K17709" wurden 26 Artikel gefunden!
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Human CYP2B6 (Cytochrome P450 2B6) ELISA Kit
Artikelnummer: ELK-ELK5323.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CYP2B6. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CYP2B6....
| Schlagworte: | CYPIIB6, Cytochrome P450 2B6, Cytochrome P450 IIB1, 1,4-cineole 2-exo-monooxygenase |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
(Z)-4-hydroxy Tamoxifen
Artikelnummer: Cay14854-1
(Z)-4-hydroxy Tamoxifen is an active metabolite of the estrogen receptor (ER) modulator tamoxifen (Cay-13258). It is primarily formed from tamoxifen by the cytochrome P450 (CYP) isoforms CYP2D6 and CYP2B6. (Z)-4-hydroxy Tamoxifen (10 nM) decreases progesterone receptor (PR) mRNA expression induced by the estrogen...
| Schlagworte: | trans-4-hydroxy Tamoxifen, ICI 79280, 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol |
| Anwendung: | Tamoxifen metabolite |
| CAS | 68047-06-3 |
| MW: | 387.5 D |
ab 50,00 €
2-Phenyl-2-(1-piperidinyl)propane
Artikelnummer: Cay17799-10
2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM, IC50 = 5.1 µM). It is 15-fold more selective for inhibition of CYP2B6 over CYP2D6 and 40-60-fold more selective for CYP2B6 over CYP1A2, CYP2A6, CYP2Cs, and...
| Schlagworte: | 1-(alpha,alpha-dimethylbenzyl)-Piperidine, PPP, 1-(1-methyl-1-phenylethyl)-piperidine |
| Anwendung: | CYP2B6 inactivator |
| CAS | 92321-29-4 |
| MW: | 203.3 D |
ab 60,00 €
Human CYP2B6 / Cytochrome P450 2B6 protein ELISA Kit
Artikelnummer: G-HUFI00566.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-CYP2B6Antibody
Artikelnummer: NSJ-R34297-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Cytochrome P450, family 2, subfamily B, polypeptide 6 Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an...
| Schlagworte: | Anti-CYP2B6, Anti-CYPIIB6, EC=1.14.13.-, Anti-Cytochrome P450 2B6, Anti-Cytochrome P450 IIB1, Anti-1,4-cineole... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
4'-hydroxy Tamoxifen
Artikelnummer: Cay19519-5
4'-hydroxy Tamoxifen is an estrogen receptor (ER) antagonist (IC50 = 2.4 nM for the rabbit receptor) and active metabolite of tamoxifen (Cay-13258, Cay-11629). It is formed from tamoxifen by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP2B6, and CYP2C19. 4'-hydroxy Tamoxifen inhibits the proliferation of...
| Schlagworte: | 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-phenol |
| Anwendung: | Tamoxifen CYP2D6 / CYP2B6 metabolite |
| CAS | 82413-23-8 |
| MW: | 387.5 D |
ab 222,00 €
Anti-CYP2B6
Artikelnummer: E-AB-16374.120
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression...
| Schlagworte: | Anti-CYP2B6, Anti-CYPIIB6, EC=1.14.13.-, Anti-Cytochrome P450 2B6, Anti-Cytochrome P450 IIB1, Anti-1,4-cineole... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 71,00 €
(+)-Cedrol
Artikelnummer: Cay25769-100
(+)-Cedrol is a sesquiterpene alcohol that has been used in Cannabis testing and has diverse biological activities. It inhibits the growth of L. sulphureus, G. trabeum, L. betulina, and T. versicolor wood decay fungi when used at a concentration of 100 µg/ml. (+)-Cedrol inhibits the cytochrome P450 (CYP) isoforms...
| Schlagworte: | alpha-Cedrol, (3R,3aS,6R,7R,8aS)-octahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-6-ol |
| Anwendung: | Bioactive sesquiterpene alcohol, CYP2B6 & CYP3A4 inhibitor |
| CAS | 77-53-2 |
| MW: | 222.4 D |
ab 92,00 €
Anti-CYP2B6
Artikelnummer: E-AB-63706.120
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression...
| Schlagworte: | Anti-CYP2B6, Anti-CYPIIB6, EC=1.14.13.-, Anti-Cytochrome P450 2B6, Anti-Cytochrome P450 IIB1, Anti-1,4-cineole... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
8-hydroxy Efavirenz
Artikelnummer: Cay27853-1
8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz (Cay-14412). 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic...
| Schlagworte: | (4S)-6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one |
| Anwendung: | Oxidative metabolite |
| CAS | 205754-33-2 |
| MW: | 331.7 D |
810,00 €
Anti-CYP2B6
Artikelnummer: G-CAB1463.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 352,00 €
Anti-CYP2B6
Artikelnummer: ATA-HPA062973.100
Protein function: A cytochrome P450 monooxygenase involved in the metabolism of endocannabinoids and steroids (PubMed:21289075, PubMed:12865317). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via...
| Schlagworte: | Anti-CYPIIB6, Anti-Cytochrome P450 2B6, Anti-Cytochrome P450 IIB1, Anti-1,4-cineole 2-exo-monooxygenase |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €