Zu "K17691" wurden 22 Artikel gefunden!
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Cobicistat
Artikelnummer: Cay23433-10
Cobicistat is an inhibitor of the cytochrome P450 (CYP) isomer CYP3A (IC50s = 30-285 nM for CYP3A metabolism of various HIV protease inhibitors). It is selective for CYP3A over other CYP isomers (IC50 = >25 µM for CYP1A2, 2C8, 2C9, and 2C19). Cobicistat does not inhibit HIV-1 protease (IC50 = >30 µM) or affect HIV...
| Schlagworte: | GS-9350,... |
| Anwendung: | CYP3A inhibitor |
| CAS | 1004316-88-4 |
| MW: | 776 D |
ab 56,00 €
16alpha-hydroxy Prednisolone
Artikelnummer: Cay27169-25
16alpha-hydroxy Prednisolone is a metabolite of 22(R)-budesonide. It is formed from 22(R)-budesonide by the cytochrome P450 (CYP) isoform CYP3A in human liver microsomesFormal Name: (11beta,16alpha)-11,16,17,21-tetrahydroxy-pregna-1,4-diene-3,20-dione. CAS Number: 13951-70-7. Molecular Formula: C21H28O6. Formula...
| Schlagworte: | (11beta,16alpha)-11,16,17,21-tetrahydroxy-pregna-1,4-diene-3,20-dione |
| Anwendung: | 22(R)-Budesonide metabolite |
| CAS | 13951-70-7 |
| MW: | 376.4 D |
ab 49,00 €
Anti-CYP3A7
Artikelnummer: G-PACO22778.100
CYP3A7 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, WB applications. CYP3A7 Antibody is a high quality polyclonal antibody for research use only.. Protein function: A cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and...
| Schlagworte: | Anti-P450HLp2, Anti-CYPIIIA7, Anti-Cytochrome P450 3A7, Anti-Cytochrome P450-HFLA |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
559,00 €
Human CYP3A7 (Cytochrome P450 3A7) ELISA Kit
Artikelnummer: ELK-ELK7465.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CYP3A7. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CYP3A7....
| Schlagworte: | CYPIIIA7, P450HLp2, Cytochrome P450 3A7, Cytochrome P450-HFLA |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Cytochrome P450 3A7 (CYP3A7), human, recombinant
Artikelnummer: CSB-EP006444HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-503aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MDLIPNLAVE TWLLLAVSLI LLYLYGTRTH GLFKKLGIPG PTPLPFLGNA LSFRKGYWTF DMECYKKYRK VWGIYDCQQP MLAITDPDMI KTVLVKECYS VFTNRRPFGP VGFMKNAISI AEDEEWKRIR...
| Schlagworte: | CYPIIIA7, P450HLp2, Cytochrome P450 3A7, Cytochrome P450-HFLA, Recombinant Human Cytochrome P450 3A7 (CYP3A7) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 64.4 kD |
ab 292,00 €
Anti-CYP3A7
Artikelnummer: CSB-PA007546.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-P450HLp2, Anti-CYPIIIA7, Anti-Cytochrome P450 3A7, Anti-Cytochrome P450-HFLA, Aryl hydrocarbon hydroxylase antibody,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
Anti-CYP3A7
Artikelnummer: CSB-PA929315.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-P450HLp2, Anti-CYPIIIA7, Anti-Cytochrome P450 3A7, Anti-Cytochrome P450-HFLA, Cytochrome P450, family 3, subfamily A,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
284,00 €
NEU
CYP3A7 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-03881-100ug
Description: CYP3A7 Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is P24462.
| Schlagworte: | Cytochrome P450-HFLA , CYPIIIA7 , Cytochrome P450 3A7 , P450HLp2 , CYP3A7 |
| MW: | 64.4 kD |
ab 93,00 €
N-desmethyl Diltiazem (hydrochloride)
Artikelnummer: Cay34977-25
N-desmethyl Diltiazem is an active metabolite of the calcium channel inhibitor diltiazem. It is formed from diltiazem by the cytochrome P450 (CYP) isoforms CYP3A4, CYP3A5, and CYP3A7. N-desmethyl Diltiazem binds to isolated rat cerebral cortex homogenates (IC50 = 323 nM) and inhibits spontaneous contractions in...
| Schlagworte: | 3-(acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one, monohydrochloride |
| Anwendung: | Diltiazem active metabolite |
| CAS | 130606-60-9 |
| MW: | 437 D |
ab 44,00 €
CYP3A7 (human), recombinant protein
Artikelnummer: ABS-PP-4400-L.100
Protein function: A cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and vitamins during embryogenesis (PubMed:9555064, PubMed:11093772, PubMed:14559847, PubMed:12865317, PubMed:17178770). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the...
| Schlagworte: | Cytochrome P450 3A7, CYPIIIA7, Cytochrome P450-HFLA, P450HLp2, Recombinant Human CYP3A7 Protein |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 26 kD |
ab 115,00 €
Anti-CYP3A7 (Cytochrome P450-HFLA, CYPIIIA7, Cytochrome...
Artikelnummer: C8929-04C.50
CYP3A7 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is...
| Schlagworte: | EC=1.14.14.1 |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
850,00 €
Cytochrome P450 3A7 BioAssay(TM) ELISA Kit
Artikelnummer: 471974.96
Sample Type:, Cell line of choice, Intended Use: The Cytochrome P450 3A7 Colorimetric Cell-Based ELISA allows for qualitative detection of CytochromeP4503A7 in plated and fixed cells. Sensitivity: >5000cells/well, Assay Time: 4.5 hours, Reactivity: Human, Detection Method: Colorimetric 450 nm, Format: Cell-Based...
| Schlagworte: | P450HLp2, CYPIIIA7, Cytochrome P450 3A7, Cytochrome P450-HFLA |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
920,00 €