Zu "K17689" wurden 86 Artikel gefunden!

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11beta-hydroxy Testosterone
11beta-hydroxy Testosterone

Artikelnummer: Cay38301-1

11beta-hydroxy Testosterone is a metabolite of testosterone. It is formed from testosterone primarily by the cytochrome P450 (CYP) isoform CYP3A4. Formal name: 11beta,17beta-dihydroxy-androst-4-en-3-one. CAS Number: 1816-85-9. Synonyms: NSC 12168. Molecular Formula: C19H28O3. Formula Weight: 304.4. Purity: >95%....
Schlagworte: NSC 12168, 11beta,17beta-dihydroxy-androst-4-en-3-one
Anwendung: Testosterone metabolite
CAS 1816-85-9
MW: 304.4 D
ab 34,00 €
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6beta-hydroxy Triamcinolone acetonide
6beta-hydroxy Triamcinolone acetonide

Artikelnummer: Cay40122-1

6beta-hydroxy Triamcinolone acetonide is a metabolite of the synthetic corticosteroid triamcinolone acetonide (Cay-18026). It is formed from triamcinolone acetonide by the cytochrome P450 (CYP) isoforms CYP3A4, CYP3A5, and CYP3A7. 6beta-hydroxy Triamcinolone acetonide has been found in wastewater effluent. Formal...
Schlagworte: 6beta-hydroxy TrA, 9-fluoro-6beta,11beta,21-trihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Anwendung: Triamcinolone acetonide metabolite
CAS 3869-32-7
MW: 450.5 D
636,00 €
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-10 %
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Human CYP3A4 (Cytochrome P450 3A4) ELISA Kit
Human CYP3A4 (Cytochrome P450 3A4) ELISA Kit

Artikelnummer: ELK-ELK3947.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CYP3A4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CYP3A4....
Schlagworte: CYP3A3, CYPIIIA3, CYPIIIA4, Nifedipine oxidase, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome...
Anwendung: ELISA
Spezies-Reaktivität: human
365,00 € ab 328,50 €
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6-hydroxy Buspirone
6-hydroxy Buspirone

Artikelnummer: Cay39807-1

6-hydroxy Buspirone is an active metabolite of the anxiolytic buspirone. It is formed from buspirone by the cytochrome P450 (CYP) isoform CYP3A4. 6-hydroxy Buspirone binds to the serotonin (5-HT) receptor subtype 5-HT1A in rat hippocampus and dorsal raphe (EC50s = 4 and 1 µM, respectively) and is a dopamine D2, D3,...
Schlagworte: BMS-52821, BMY 28674, 6-hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione
Anwendung: Active buspirone metabolite
CAS 125481-61-0
MW: 401.5 D
ab 314,00 €
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6beta-hydroxy Dexamethasone
6beta-hydroxy Dexamethasone

Artikelnummer: Cay22099-2.5

6beta-hydroxy Dexamethasone is an active metabolite of the synthetic glucocorticoid dexamethasone (Cay-11015). It is formed from dexamethasone by the cytochrome P450 (CYP) isoform CYP3A4. 6beta-hydroxy Dexamethasone (1 mg/kg) reduces cortisol (hydrocortisone, Cay-20739) production in rats.Formal Name:...
Schlagworte: 6beta-hydroxydexamethasone, 6-hydroxyDEX, 6OH-DEX,...
Anwendung: Dexamethasone active metabolite
CAS 55879-47-5
MW: 408.5 D
374,00 €
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7alpha-hydroxy-3-oxo-5beta-Cholan-24-oic Acid
7alpha-hydroxy-3-oxo-5beta-Cholan-24-oic Acid

Artikelnummer: Cay38159-10

7alpha-hydroxy-3-oxo-5beta-Cholan-24-oic acid is a metabolite of chenodeoxycholic acid (Cay-35346, Cay-10011286). It is formed from chenodeoxycholic acid primarily by the cytochrome P450 (CYP) isoform CYP3A4 but also by CYP3A5 and other P450 enzymes at lower rates.Formal Name:...
Schlagworte: 3-keto-7alpha-hydroxy-5beta-Cholanic Acid, 3-Oxochenodeoxycholic Acid, (5beta)-7alpha-hydroxy-3-oxo-cholan-24-oic acid
Anwendung: Chenodeoxycholic acid metabolite
CAS 4185-00-6
MW: 390.6 D
ab 117,00 €
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N-Acetyl-4-benzoquinone imine
N-Acetyl-4-benzoquinone imine

Artikelnummer: Cay16115-500

N-Acetyl-4-benzoquinone imine (NAPQI) is a cytochrome P450 3A4 and 2E1 metabolite of acetaminophen that can be toxic to the liver when acetaminophen is consumed in large doses. At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione. However, following toxic doses of...
Schlagworte: N-Acetyl-p-benzoquinonimine, NAPQI, N-(4-oxo-2,5-cyclohexadien-1-ylidene)-acetamide
Anwendung: Paracetamol metabolite
CAS 50700-49-7
MW: 149.2 D
ab 158,00 €
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Norhydrocodone (hydrochloride)
Norhydrocodone (hydrochloride)

Artikelnummer: Cay15901-1

Norhydrocodone (Cay-15901) is an analytical reference material categorized as an opioid. It is an active metabolite of hydrocodone (Cay-ISO60144). This product is intended for research and forensic applications.Formal Name: 4,5alpha-epoxy-3-methoxy-morphinan-6-one, monohydrochloride. CAS Number: 71968-04-2....
Schlagworte: 4,5alpha-epoxy-3-methoxy-morphinan-6-one, monohydrochloride
Anwendung: Analytical reference material, Opioid, Active hydrocodone metabolite
CAS 71968-04-2
MW: 321.8 D
ab 109,00 €
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EDDP (perchlorate) (CRM)
EDDP (perchlorate) (CRM)

Artikelnummer: CayISO60143-1

EDDP (perchlorate) (CRM) (Cay-ISO60143) is a certified reference material that is categorized as a metabolite. It is an inactive metabolite of methadone (Cay-ISO00145, Cay-ISO60145), produced by N-demethylation in the liver, primarily by cytochrome P450 (CYP) isoform 3A4. The activity of CYP3A4 varies widely among...
Schlagworte: 5-ethyl-3,4-dihydro-1,2-dimethyl-4,4-diphenyl-2H-pyrrolium, perchlorate
Anwendung: Certified reference material, inactive methadone metabolite
CAS 31161-17-8
MW: 377.9 D
28,00 €
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Voriconazole N-oxide
Voriconazole N-oxide

Artikelnummer: Cay28047-1

Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole (Cay-15633). It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19.Formal Name:...
Schlagworte: UK 121265,...
Anwendung: Major voriconazole metabolite
CAS 618109-05-0
MW: 365.3 D
ab 218,00 €
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SB 202474
SB 202474

Artikelnummer: Cay18749-1

SB 202190 (Cay-10010399) and SB 203580 (Cay-13067) are potent, selective inhibitors of the MAP kinases p38alpha and p38beta. SB 202474 is a structural analog of SB 202190 and SB 203580 that is used as a negative control in studies of p38 inhibition.Formal Name:...
Schlagworte: 4-[4-ethyl-2-(4-methoxyphenyl)-1H-imidazol-5-yl]-pyridine
Anwendung: Irreversible CYP3A inhibitor
CAS 172747-50-1
MW: 279.3 D
189,00 €
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Naringin
Naringin

Artikelnummer: Cay17923-25

Naringin is a natural flavanone glycoside formed from naringenin and neohesperidose. It undergoes extensive metabolism in the liver, giving rise to naringenin and other bioactive metabolites that have anti-oxidant, anti-inflammatory, and anti-apoptotic effects. Naringin is a weak inhibitor of CYP3A4, providing 14%...
Schlagworte: NSC 5548,...
Anwendung: Weak CYP3A4 inhibitor
CAS 10236-47-2
MW: 580.5 D
ab 50,00 €
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