Zu "K17683" wurden 27 Artikel gefunden!
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7-Methylcoumarin
Artikelnummer: CDX-M0116-G025
7-Methylcoumarin is an inhibitor for CYP2A6. It has strong hepatoprotective activity, which could be attributed to its potent antioxidant effects. 7-Methylcoumarin has moderate antimicrobial activity. The compound can be used as internal standard during HPLC analysis.
| Schlagworte: | 7-Methyl-2H-chromen-2-one, NSC19511, BRN0122625 |
| Anwendung: | CYP2A6 inhibitor |
| CAS | 2445-83-2 |
| MW: | 160.17 D |
131,00 €
trans-3'-Hydroxycotinine
Artikelnummer: Cay16100-1
trans-3'-Hydroxycotinine (3HC) is a product of CYP2A6 metabolism of the primary nicotine metabolite, cotinine (Cay-15314). Cotinine has a longer metabolic half-life compared to 3HC (16 hours vs. 5 hours). The ratio of 3HC to cotinine, termed the nicotine metabolite ratio, correlates with nicotine clearance from the...
| Schlagworte: | 3HC, 3R-hydroxy-1-methyl-5S-(3-pyridinyl)-2-pyrrolidinone |
| Anwendung: | Nicotine metabolite, CYP2A6 activity biomarker |
| CAS | 34834-67-8 |
| MW: | 192.2 D |
ab 77,00 €
beta-Nicotyrine
Artikelnummer: Cay16333-1
beta-Nicotyrine is an alkaloid that has been found in tobacco. It reduces the number of dsDNA breaks induced by the tobacco-specific carcinogen nitrosamine (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, Cay-16414) in a comet assay using HepaRG hepatocellular carcinoma cells when used at concentrations of 5 and 50...
| Schlagworte: | NSC 127943, NSC 407276, alpha-Nicotyrine, 3-(1-methyl-1H-pyrrol-2-yl)-pyridine |
| Anwendung: | Nicotine metabolite, CYP2A6 / CYP2A13 inhibitor |
| CAS | 487-19-4 |
| MW: | 158.2 D |
ab 65,00 €
(±)-Cotinine-d3
Artikelnummer: Cay15805-10
(±)-Cotinine-d3 is intended for use as an internal standard for the quantification of cotinine by GC- or LC-MS. Cotinine is an alkaloid found in tobacco and a major metabolite of nicotine (Cay-16535). It is formed by oxidation of nicotine by the cytochrome P450 (CYP) isoform CYP2A6.Formal Name:...
| Schlagworte: | 1-(methyl-d3)-5-(3-pyridinyl)-2-pyrrolidinone |
| Anwendung: | GC-MS, LC-MS, Internal standard, Nicotine metabolite |
| CAS | 110952-70-0 |
| MW: | 179.2 D |
ab 110,00 €
Human CYP2A6 ELISA Kit
Artikelnummer: G-HUFI02376.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-CYP2A6
Artikelnummer: G-CAB15044.100
IF 1:50 - 1:200. Protein function: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4- cineole 2-exo-monooxygenase....
| Schlagworte: | Anti-CYP2A6, Anti-CYP2A3, Anti-CYPIIA6, EC=1.14.13.-, Anti-Cytochrome P450(I), Anti-Cytochrome P450 2A6, Anti-Cytochrome... |
| Anwendung: | IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 352,00 €
Anti-CYP2A6
Artikelnummer: G-CAB5815.100
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 352,00 €
Anti-CYP2A6/CYP2A7/CYP2A13 (PACO01811)
Artikelnummer: G-PACO01811.50
CYP2A6/CYP2A7/CYP2A13 Antibody from Assay Genie with reactivity against Human and for use in ELISA, WB applications. CYP2A6/CYP2A7/CYP2A13 Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the...
| Schlagworte: | Anti-CYP2A6, Anti-CYP2A3, Anti-CYPIIA6, EC=1.14.13.-, Anti-Cytochrome P450(I), Anti-Cytochrome P450 2A6, Anti-Cytochrome... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
320,00 €
Anti-CYP2A7
Artikelnummer: G-PACO06399.50
CYP2A7 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, WB, IHC applications. CYP2A7 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes,...
| Schlagworte: | Anti-CYP2A7, Anti-CYPIIA7, EC=1.14.14.1, Anti-Cytochrome P450 2A7, Anti-Cytochrome P450 IIA4 |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
320,00 €
Anti-CYP2A7
Artikelnummer: G-PACO22785.100
CYP2A7 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, WB applications. CYP2A7 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this...
| Schlagworte: | Anti-CYP2A7, Anti-CYPIIA7, EC=1.14.14.1, Anti-Cytochrome P450 2A7, Anti-Cytochrome P450 IIA4 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
448,00 €
Hydroxymetronidazole
Artikelnummer: Cay35249-1
Hydroxymetronidazole is an active metabolite of the antibiotic metronidazole (Cay-9002409). It is formed from metronidazole primarily by the cytochrome P450 (CYP) isoform CYP2A6. Hydroxymetronidazole is active against B. fragilis, B. thetaiotaomicron, B. distasonis, and B. ovatus (MICs = 1, 2, 1, and 2 µg/ml,...
| Schlagworte: | hydroxy-MNZ, 2-(hydroxymethyl)-5-nitro-1H-imidazole-1-ethanol |
| Anwendung: | Metronidazole active metabolite |
| CAS | 4812-40-2 |
| MW: | 187.2 D |
ab 42,00 €
Anti-CYP2A6
Artikelnummer: E-AB-92681.120
This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression...
| Schlagworte: | CYP2A3, CYP2A6, CYPIIA6, EC=1.14.14.-, Cytochrome P450(I), Cytochrome P450 2A6, Cytochrome P450 IIA3, Coumarin... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 198,00 €