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Zu "K17683" wurden 36 Artikel gefunden!
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Artikelnummer: Cay15805-10
(±)-Cotinine-d3 is intended for use as an internal standard for the quantification of cotinine by GC- or LC-MS. Cotinine is an alkaloid found in tobacco and a major metabolite of nicotine (Cay-16535). It is formed by oxidation of nicotine by the cytochrome P450 (CYP) isoform CYP2A6.Formal Name:...
| Schlagworte: | 1-(methyl-d3)-5-(3-pyridinyl)-2-pyrrolidinone |
| Anwendung: | GC-MS, LC-MS, internal standard, nicotine metabolite |
| CAS | 110952-70-0 |
| MW: | 179.2 D |
ab 123,00 €
Artikelnummer: Cay16100-1
trans-3'-Hydroxycotinine (3HC) is a product of CYP2A6 metabolism of the primary nicotine metabolite, cotinine (Cay-15314). Cotinine has a longer metabolic half-life compared to 3HC (16 hours vs. 5 hours). The ratio of 3HC to cotinine, termed the nicotine metabolite ratio, correlates with nicotine clearance from the...
| Schlagworte: | 3HC, 3R-hydroxy-1-methyl-5S-(3-pyridinyl)-2-pyrrolidinone |
| Anwendung: | Nicotine metabolite, CYP2A6 activity biomarker |
| CAS | 34834-67-8 |
| MW: | 192.2 D |
ab 85,00 €
Artikelnummer: Cay16333-1
beta-Nicotyrine is an alkaloid that has been found in tobacco. It reduces the number of dsDNA breaks induced by the tobacco-specific carcinogen nitrosamine (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, Cay-16414) in a comet assay using HepaRG hepatocellular carcinoma cells when used at concentrations of 5 and 50...
| Schlagworte: | NSC 127943, NSC 407276, alpha-Nicotyrine, 3-(1-methyl-1H-pyrrol-2-yl)-pyridine |
| Anwendung: | Nicotine metabolite, CYP2A6 / CYP2A13 inhibitor |
| CAS | 487-19-4 |
| MW: | 158.2 D |
ab 72,00 €
Artikelnummer: G-HUFI02376.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: G-PACO01811.50
CYP2A6/CYP2A7/CYP2A13 Antibody from Assay Genie with reactivity against Human and for use in ELISA, WB applications. CYP2A6/CYP2A7/CYP2A13 Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the...
| Schlagworte: | Anti-CYP2A6, Anti-CYP2A3, Anti-CYPIIA6, EC=1.14.13.-, Anti-Cytochrome P450(I), Anti-Cytochrome P450 2A6, Anti-Cytochrome... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
225,00 €
Artikelnummer: Cay35249-1
Hydroxymetronidazole is an active metabolite of the antibiotic metronidazole (Cay-9002409). It is formed from metronidazole primarily by the cytochrome P450 (CYP) isoform CYP2A6. Hydroxymetronidazole is active against B. fragilis, B. thetaiotaomicron, B. distasonis, and B. ovatus (MICs = 1, 2, 1, and 2 µg/ml,...
| Schlagworte: | hydroxy-MNZ, 2-(hydroxymethyl)-5-nitro-1H-imidazole-1-ethanol |
| Anwendung: | Metronidazole active metabolite |
| CAS | 4812-40-2 |
| MW: | 187.2 D |
ab 48,00 €
Artikelnummer: CDX-M0116-G025
7-Methylcoumarin is an inhibitor for CYP2A6. It has strong hepatoprotective activity, which could be attributed to its potent antioxidant effects. 7-Methylcoumarin has moderate antimicrobial activity. The compound can be used as internal standard during HPLC analysis.
| Schlagworte: | 7-Methyl-2H-chromen-2-one, NSC19511, BRN0122625 |
| Anwendung: | CYP2A6 inhibitor |
| CAS | 2445-83-2 |
| MW: | 160.17 D |
131,00 €
Artikelnummer: CSB-EP006410HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 29-494aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: SKGKLPPGPT PLPFIGNYLQ LNTEQMYNSL MKISERYGPV FTIHLGPRRV VVLCGHDAVR EALVDQAEEF SGRGEQATFD WVFKGYGVVF SNGERAKQLR RFSIATLRDF...
| Schlagworte: | CYP2A6, CYP2A3, CYPIIA6, EC=1.14.13.-, Cytochrome P450(I), Cytochrome P450 2A6, Cytochrome P450 IIA3, Coumarin... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 60.8 kD |
ab 292,00 €
Artikelnummer: CSB-EP006410HUe1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 29-494aa. Protein Length: Partial. Tag Info: Tag-Free. Target Protein Sequence: SKGKLPPGPT PLPFIGNYLQ LNTEQMYNSL MKISERYGPV FTIHLGPRRV VVLCGHDAVR EALVDQAEEF SGRGEQATFD WVFKGYGVVF SNGERAKQLR RFSIATLRDF GVGKRGIEER IQEEAGFLID ALRGTGGANI DPTFFLSRTV...
| Schlagworte: | CYP2A6, CYP2A3, CYPIIA6, EC=1.14.13.-, Cytochrome P450(I), Cytochrome P450 2A6, Cytochrome P450 IIA3, Coumarin... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 53.5 kD |
ab 439,00 €
Artikelnummer: CSB-PA001953.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYP2A7, Anti-CYPIIA7, EC=1.14.14.1, Anti-Cytochrome P450 2A7, Anti-Cytochrome P450 IIA4, CYP2A7Cytochrome P450 2A7... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
126,00 €
Artikelnummer: CSB-PA004739.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYP2A6, Anti-CYP2A3, Anti-CYPIIA6, EC=1.14.13.-, Anti-Cytochrome P450(I), Anti-Cytochrome P450 2A6, Anti-Cytochrome... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
Artikelnummer: CSB-PA007526.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYP2A6, Anti-CYP2A3, Anti-CYPIIA6, EC=1.14.13.-, Anti-Cytochrome P450(I), Anti-Cytochrome P450 2A6, Anti-Cytochrome... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €