Zu "K17399" wurden 35 Artikel gefunden!
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SGI-1027
Artikelnummer: Cay11165-5
SGI-1027 is an inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 µM, respectively, with Poly(dI-dC) as the substrate). It has been shown to cause the degradation of DNMT1 and to reactivate silenced tumor suppressor genes by reducing CpG island hypermethylation.Formal Name:...
| Schlagworte: | DNA Methyltransferase Inhibitor II, N-[4-[(2-amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)-benzamide |
| Anwendung: | DNMT1 / DNMT3A / DNMT3B inhibitor |
| CAS | 1020149-73-8 |
| MW: | 461.5 D |
ab 58,00 €
Anti-DNMT3B
Artikelnummer: E-AB-60798.60
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo...
| Schlagworte: | Anti-Dnmt3b, Anti-DNMT3B, Anti-M.HsaIIIB, EC=2.1.1.37, Anti-DNA MTase HsaIIIB, Anti-DNA methyltransferase HsaIIIB,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 243,00 €
Anti-DNMT3B
Artikelnummer: BPS-25219
DNMT3B (UniProtKB/Swiss Prot entry Q9UBC3) catalyses the genome wide de novo methylation of CpG residues, which regulates gene expression. DNMT3B is essential for development. DNA methylation on CpG residues is coordinated with methylation of histones. Six different isoforms of DNMT3B, produced by alternative...
| Schlagworte: | Anti-DNMT3B, Anti-Dnmt3b, Anti-M.HsaIIIB, EC=2.1.1.37, Anti-DNA MTase HsaIIIB, Anti-DNA methyltransferase HsaIIIB,... |
| Anwendung: | ELISA, WB, IF |
| Spezies-Reaktivität: | human |
933,00 €
DNMT3B, active, murine recombinant, N-terminal His-tag
Artikelnummer: BPS-51105
Murine DNA methyltransferase 3beta (DNMT3B) (GenBank Accession No. NM_001003961), amino acids 2-859 (end), with N-terminal His-tag and C-terminal FLAG-tag, MW = 99 kDa, expressed in Sf9 cells via a Baculovirus expression system.
| Schlagworte: | Dnmt3b, M.MmuIIIB, EC=2.1.1.37, DNA MTase MmuIIIB, DNA methyltransferase MmuIIIB, DNA (cytosine-5)-methyltransferase 3B, |
| Anwendung: | Enzyme kinetics, inhibitor screening, profiling |
| MW: | 99 kD |
708,00 €
DNMT3B Assay kit
Artikelnummer: BPS-52034
The DNMT3B Direct Activity Assay Kit is designed to measure DNMT3B activity using purified DNMT3B/3L or cell extracts containing DNMT3B. The DNMT3B Direct Activity Assay Kit comes in a convenient format, with a 96-well plate precoated with DNMT substrate
| Schlagworte: | DNA (cytosine-5)-methyltransferase 3B, Dnmt3b, EC=2.1.1.37, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, M.HsaIIIB... |
| Anwendung: | Enzyme kinetics, HTS |
1.563,00 €
Anti-Dnmt3b
Artikelnummer: NSJ-F40611-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3b is a DNA methyltransferase which is...
| Schlagworte: | Anti-Dnmt3b, Anti-DNMT3B, Anti-M.HsaIIIB, EC=2.1.1.37, Anti-DNA MTase HsaIIIB, Anti-DNA methyltransferase HsaIIIB,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-Dnmt3b
Artikelnummer: ARG54845.100
Protein function: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as...
| Schlagworte: | Anti-DNMT3B, Anti-Dnmt3b, Anti-M.HsaIIIB, EC=2.1.1.37, Anti-DNA MTase HsaIIIB, Anti-DNA methyltransferase HsaIIIB,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
616,00 €
Anti-DNMT3B
Artikelnummer: ATA-HPA001595.100
Protein function: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as...
| Schlagworte: | Anti-Dnmt3b, Anti-DNMT3B, Anti-M.HsaIIIB, EC=2.1.1.37, Anti-DNA MTase HsaIIIB, Anti-DNA methyltransferase HsaIIIB,... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
DNMT3B/DNMT3L Complex (human, recombinant)
Artikelnummer: Cay36311-10
Synonyms: DNA (Cytosine-5)-Methyltransferase 3B, DNA (Cytosine-5)-Methyltransferase 3-Like, DNA Methyltransferase HsaIIIB, DNA MTase HsaIIIB, M.HsaIIIB. Purity: >90% estimated by SDS-PAGE. Source: Active recombinant human N-terminal GST-tagged DNMT3B and N-terminal His-tagged DNMT3L expressed in insect cells. Amino...
| Schlagworte: | DNA (Cytosine-5)-Methyltransferase 3B, DNA (Cytosine-5)-Methyltransferase 3-Like, DNA Methyltransferase HsaIIIB, DNA MTase... |
| Anwendung: | Enzyme assays |
| Ursprungsart: | human |
801,00 €
Anti-Dnmt3b
Artikelnummer: NSJ-RQ6614
0.5mg/ml if reconstituted with 0.2ml sterile DI water. DNA (cytosine-5-)-methyltransferase 3 beta, is an enzyme that in humans in encoded by the DNMT3B gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have...
| Schlagworte: | Anti-DNMT3B, Anti-Dnmt3b, Anti-M.HsaIIIB, EC=2.1.1.37, Anti-DNA MTase HsaIIIB, Anti-DNA methyltransferase HsaIIIB,... |
| Anwendung: | WB, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey |
790,00 €
Anti-DNMT3b
Artikelnummer: NSJ-RQ6863
0.5mg/ml if reconstituted with 0.2ml sterile DI water. DNA (cytosine-5-)-methyltransferase 3 beta, is an enzyme that in humans in encoded by the DNMT3B gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have...
| Schlagworte: | Anti-DNMT3B, Anti-Dnmt3b, Anti-M.HsaIIIB, EC=2.1.1.37, Anti-DNA MTase HsaIIIB, Anti-DNA methyltransferase HsaIIIB,... |
| Anwendung: | WB, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
790,00 €
Anti-DNMT3B
Artikelnummer: NSJ-RQ6973
0.5mg/ml if reconstituted with 0.2ml sterile DI water. DNA (cytosine-5-)-methyltransferase 3 beta, is an enzyme that in humans in encoded by the DNMT3B gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have...
| Schlagworte: | Anti-Dnmt3b, Anti-DNMT3B, Anti-M.HsaIIIB, EC=2.1.1.37, Anti-DNA MTase HsaIIIB, Anti-DNA methyltransferase HsaIIIB,... |
| Anwendung: | WB, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey, rat |
790,00 €