Zu "K17398" wurden 62 Artikel gefunden!
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Anti-DNMT3A / DNA (cytosine-5)-methyltransferase 3A
Artikelnummer: NSJ-FY13240
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. DNMT3A antibody detects DNA (cytosine-5)-methyltransferase 3A, an enzyme responsible for establishing de novo DNA methylation patterns during development and differentiation. The UniProt recommended name is DNA (cytosine-5)-methyltransferase...
| Schlagworte: | Anti-DNMT3A, Anti-DNA methyltransferase HsaIIIA, Anti-Cysteine methyltransferase DNMT3A, Anti-DNA... |
| Anwendung: | WB, IHC, ICC, IF, IP, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
SGI-1027
Artikelnummer: Cay11165-10
SGI-1027 is an inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 µM, respectively, with Poly(dI-dC) as the substrate). It has been shown to cause the degradation of DNMT1 and to reactivate silenced tumor suppressor genes by reducing CpG island hypermethylation.Formal Name:...
| Schlagworte: | DNA Methyltransferase Inhibitor II, N-[4-[(2-amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)-benzamide |
| Anwendung: | DNMT1 / DNMT3A / DNMT3B inhibitor |
| CAS | 1020149-73-8 |
| MW: | 461.5 D |
ab 56,00 €
Anti-DNA Methyltransferase 3a (Clone 64B1446)
Artikelnummer: Cay13484-1
Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, three...
| Schlagworte: | DNMT3a |
| Anwendung: | WB, IF/ICC, ChIP, IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
549,00 €
Anti-Dnmt3a, clone 64B1446
Artikelnummer: 200-301-H70
Anti-Dnmt3a Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Dnmt3a from human and mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Dnmt3a from other sources has not been determined. Protein function: Required for...
| Schlagworte: | Anti-Dnmt3a, Anti-M.MmuIIIA, EC=2.1.1.37, Anti-DNA MTase MmuIIIA, Anti-DNA methyltransferase MmuIIIA, Anti-DNA... |
| Anwendung: | IFM, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
940,00 €
Azacytidine
Artikelnummer: LKT-A9602.100
| Schlagworte: | Azacitidine |
| Anwendung: | DNA methyltransferase inhibitor |
| CAS | 320-67-2 |
| MW: | 244.2 D |
ab 83,00 €
Anti-DNMT3A
Artikelnummer: A304-278A
Protein function: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate...
| Schlagworte: | Anti-Dnmt3a, Anti-DNMT3A, Anti-M.HsaIIIA, EC=2.1.1.37, Anti-DNA MTase HsaIIIA, Anti-DNA methyltransferase HsaIIIA,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-DNMT3A
Artikelnummer: BPS-25218
DNMT3A (UniProtKB/Swiss Prot entry Q9Y6K1) catalyses the genome wide de novo methylation of CpG residues. DNA methylation on CpG residues by DNMT3A regulates gene expression and is essential for development. DNMT3A is strongly expressed in embryonic stem cells, but low in adult somatic cells. DNA methylation is...
| Schlagworte: | Anti-Dnmt3a, Anti-DNMT3A, Anti-M.HsaIIIA, Anti-DNA MTase HsaIIIA, Anti-DNA methyltransferase HsaIIIA, Anti-Cysteine... |
| Anwendung: | ELISA, WB, IP |
| Spezies-Reaktivität: | human |
933,00 €
DNMT3a, active human recombinant protein
Artikelnummer: BPS-51103
Active humanDNMT3a (GenBank Accession No. NM_175629), (a-a 2-913), with N-terminal GST tag, MW=128 kDa, expressed in baculovirus expression system.
| Schlagworte: | Dnmt3a, DNMT3A, M.HsaIIIA, DNA MTase HsaIIIA, DNA methyltransferase HsaIIIA, Cysteine methyltransferase DNMT3A, DNA... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 128 kD |
715,00 €
DNMT3A Assay kit
Artikelnummer: BPS-52033
The DNMT3A Direct Activity Assay Kit is designed to measure DNMT3A activity using purified DNMT3A/3L or cell extracts containing DNMT3A. The DNMT3A Direct Activity Assay Kit comes in a convenient format, with a 96-well plate precoated with DNMT substrate,
| Schlagworte: | DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, EC=2.1.1.37, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, M.HsaIIIA... |
| Anwendung: | Enzyme kinetics, HTS |
1.373,00 €
Anti-DNA Methyltransferase 3a (Clone 64B814.1)
Artikelnummer: Cay13482-1
Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting, and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, three...
| Schlagworte: | DNMT3a |
| Anwendung: | WB, IF, ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
549,00 €
Anti-DNMT3A
Artikelnummer: E-AB-14623.120
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo...
| Schlagworte: | Anti-Dnmt3a, Anti-DNMT3A, Anti-M.HsaIIIA, EC=2.1.1.37, Anti-DNA MTase HsaIIIA, Anti-DNA methyltransferase HsaIIIA,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-Dnmt3a
Artikelnummer: NSJ-F40558-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is...
| Schlagworte: | Anti-Dnmt3a, Anti-DNMT3A, Anti-M.HsaIIIA, EC=2.1.1.37, Anti-DNA MTase HsaIIIA, Anti-DNA methyltransferase HsaIIIA,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €