Zu "K16835" wurden 30 Artikel gefunden!
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Anacetrapib
Artikelnummer: TGM-T1928-5mg
Description: Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum...
| Schlagworte: | MK-0859 |
| Anwendung: | Targets cholesteryl ester transfer protein (CETP) |
| CAS | 875446-37-0 |
| MW: | 637.51 D |
ab 31,00 €
Dalcetrapib
Artikelnummer: TGM-T6048-100mg
Description: Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 µM), increases the plasma HDL cholesterol. Target: CETP. Smiles: CCC(CC)CC1(CCCCC1)C(=O)Nc1ccccc1SC(=O)C(C)C. References: Niesor EJ, et al. J Lipid Res. 2010, 51(12), 3443-3454.
| Schlagworte: | JTT-705, RO4607381 |
| Anwendung: | Targets cholesteryl ester transfer protein (CETP) |
| CAS | 211513-37-0 |
| MW: | 389.59 D |
ab 38,00 €
Evacetrapib
Artikelnummer: TGM-T6262-100mg
Description: Evacetrapib (LY2484595) (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3. Target: CETP. Smiles:...
| Schlagworte: | LY2484595 |
| Anwendung: | Targets cholesteryl ester transfer protein (CETP) |
| CAS | 1186486-62-3 |
| MW: | 638.65 D |
ab 34,00 €
Obicetrapib calcium
Artikelnummer: TGM-T68504-100mg
Description: Obicetrapib calcium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial effect for cardiovascular disease risk reduction. Target: Others
| Anwendung: | Targets cholesteryl ester transfer protein (CETP) |
| CAS | 866399-89-5 |
| MW: | 1483.28 D |
ab 2.121,00 €
Obicetrapib
Artikelnummer: TGM-T28225-10mg
Description: Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein. Target: CETP. Smiles: N(CC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)([C@@H]2C=3C(N(C(OCC)=O)[C@H](CC)C2)=CC=C(C(F)(F)F)C3)C=4N=CC(OCCCC(O)=O)=CN4. References: Filippatos TD, et al. Cholesteryl ester transfer protein inhibitors: challenges...
| Schlagworte: | TA8995, AMG 899, AMG-899, Obicetrapib (free base), AMG899, Obicetrapib, TA-8995 |
| Anwendung: | Targets cholesteryl ester transfer protein (CETP) |
| CAS | 866399-87-3 |
| MW: | 722.6 D |
ab 194,00 €
Cholesteryl ester transfer protein (CETP), human,...
Artikelnummer: CSB-EP005267HUd8.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 18-493aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal MBP-tagged and C-terminal 6xHis-tagged. Target Protein Sequence: CSKGTSHEAG IVCRITKPAL LVLNHETAKV IQTAFQRASY PDITGEKAMM LLGQVKYGLH NIQISHLSIA SSQVELVEAK SIDVSIQNVS...
| Schlagworte: | Lipid transfer protein I, Cholesteryl ester transfer protein, Recombinant Human Cholesteryl ester transfer protein (CETP) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 96.9 kD |
ab 292,00 €
Anacetrapib
Artikelnummer: Cay21558-10
Anacetrapib is an inhibitor of cholesterol ester transfer protein (CETP) with IC50 values of 17 and 15 nM for CETP-dependent transfer of cholesterol esters and triglycerides, respectively. It decreases plasma levels of LDL and triglycerides, reduces atherosclerotic lesion sizes, and increases HDL levels in the...
| Schlagworte: | MK-0859,... |
| Anwendung: | Cholesteryl ester transfer protein inhibitor |
| CAS | 875446-37-0 |
| MW: | 637.5 D |
ab 82,00 €
Evacetrapib
Artikelnummer: Cay23670-5
Evacetrapib is a benzazepine inhibitor of cholesteryl ester transfer protein (CETP, IC50s = 5.5 and 26 nM for human recombinant and plasma-derived proteins, respectively). It is selective for CETP over a panel of cell surface and nuclear receptors with no significant inhibition at 1 µM. Evacetrapib (1-10 µM) reduces...
| Schlagworte: | trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethy... |
| Anwendung: | Cholesteryl ester transfer protein (CETP) inhibitor |
| CAS | 1186486-62-3 |
| MW: | 638.7 D |
ab 111,00 €
Torcetrapib
Artikelnummer: Cay15028-50
Torcetrapib is an inhibitor of cholesteryl ester transfer protein (CETP, IC50s = 47 and 51 nM for cholesteryl and triglyceride transfer, respectively). It is selective for CETP over phospholipid transfer protein (PLTP), lecithin:cholesterol acyltransferase (LCAT), and hepatic and lipoprotein lipases at 10 µM....
| Schlagworte: | CP 529,414,... |
| Anwendung: | CETP inhibitor |
| CAS | 262352-17-0 |
| MW: | 600.5 D |
ab 133,00 €
Anti-CETP
Artikelnummer: ARG57305.100
Protein function: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride...
| Schlagworte: | Anti-Lipid transfer protein I, Anti-Cholesteryl ester transfer protein |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Human Cholesteryl Ester Transfer Protein (CETP) ELISA Kit
Artikelnummer: ARG81216.96
Protein function: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride...
| Schlagworte: | Anti-Lipid transfer protein I, Anti-Cholesteryl ester transfer protein |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.480,00 €
Human CETP / Cholesteryl ester transfer protein ELISA Kit
Artikelnummer: G-HUFI00808.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €