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Zu "K16315" wurden 27 Artikel gefunden!
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Artikelnummer: NSJ-FY12349
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. The HASPIN antibody targets Serine/threonine-protein kinase haspin, a cell cycle-regulated kinase encoded by the GSG2 gene. Haspin is best known for phosphorylating histone H3 at threonine 3 (H3T3ph), a key mitotic modification that recruits...
| Schlagworte: | Anti-HASPIN, Anti-H-haspin, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin,... |
| Anwendung: | WB, ICC/IF, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Artikelnummer: A302-241A
Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression...
| Schlagworte: | Anti-GSG2, Anti-H-haspin, EC=2.7.11.1, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Artikelnummer: Cay19089-10
LDN-192960 is an inhibitor of haspin protein kinase and dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) with IC50 values of 10 and 48 nM, respectively. It is selective for haspin and DYRK2 over TRKB, CLK1, DYRK1A, DYRK3, ROS, HIPK1, HIPK2, PIM-1, and PIM-2 kinases (IC50s = 720-91,000...
| Schlagworte: | 3-[(2,7-dimethoxy-9-acridinyl)thio]-1-propanamine, dihydrochloride |
| Anwendung: | HASPIN / DYRK2 inhibitor |
| CAS | 2309172-48-1 |
| MW: | 401.4 D |
ab 145,00 €
Artikelnummer: TGM-T14959-5mg
Description: CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM). Target: Others. Smiles: OC(=O)C(F)(F)F.CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1. References: Huertas D, et al. Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene. 2012 Mar...
| Anwendung: | Haspin Kinase Inhibitor |
| CAS | 1333377-65-3 |
| MW: | 292.34 D |
ab 49,00 €
Artikelnummer: Cay11478-1
CHR-6494 is a haspin protein kinase inhibitor (IC50 = 2 nM) selective over 27 other protein kinases, including Aurora B kinase (IC50 > 1 µM). Haspin is a kinase necessary for mitosis that selectively phosphorylates histone 3 at the threonine 3 residue (H3T3ph). CHR-6494 decreases phosphorylation of H3T3 and arrests...
| Schlagworte: | 3-(1H-indazol-5-yl)-N-propyl-imidazo[1,2-b]pyridazin-6-amine |
| Anwendung: | Haspin Kinase Inhibitor |
| CAS | 1333377-65-3 |
| MW: | 292.3 D |
ab 49,00 €
Artikelnummer: E-AB-18068.120
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle....
| Schlagworte: | Anti-H-haspin, EC=2.7.11.1, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Artikelnummer: E-AB-19975.120
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle....
| Schlagworte: | Anti-H-haspin, EC=2.7.11.1, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Artikelnummer: ATA-HPA027422.100
Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase...
| Schlagworte: | Anti-H-haspin, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin, Anti-Haploid germ... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Artikelnummer: ATA-HPA030698.100
Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase...
| Schlagworte: | Anti-H-haspin, Anti-Germ cell-specific gene 2 protein, Anti-Serine/threonine-protein kinase haspin, Anti-Haploid germ... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Artikelnummer: TGM-T11830-100mg
Description: LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin, with IC50 values of 48 nM and 10 nM, respectively. Target: Others. Smiles: COC1=CC2=C(C=C1)N=C3C=CC(OC)=CC3=C2SCCCN.Cl.Cl. References: Cuny GD, et al. Structure-activity relationship study of...
| Anwendung: | HASPIN / DYRK2 inhibitor |
| CAS | 2309172-48-1 |
| MW: | 401.35 D |
ab 725,00 €
Artikelnummer: ARG45572.50
Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase...
| Schlagworte: | Anti-H-haspin, Anti-H-haspin, Anti-Germ cell-specific gene 2 protein, Anti-Germ cell-specific gene 2 protein,... |
| Anwendung: | FC, ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
501,00 €
Artikelnummer: ABS-PP-10677-L.100
Protein function: Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase...
| Schlagworte: | Serine/threonine-protein kinase haspin, Germ cell-specific gene 2 protein, H-haspin, Haploid germ cell-specific nuclear... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 17 kD |
ab 115,00 €