Zu "K16311" wurden 28 Artikel gefunden!
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Anti-SIK2 / Salt-inducible kinase 2
Artikelnummer: NSJ-FY13008
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. SIK2 antibody detects Salt-inducible kinase 2, a serine/threonine kinase that regulates metabolism, stress response, and cell cycle progression. The UniProt recommended name is Salt-inducible kinase 2 (SIK2). This enzyme is part of the...
| Schlagworte: | Anti-SIK2, Anti-Qin-induced kinase, Anti-Salt-inducible kinase 2, Anti-Serine/threonine-protein kinase SIK2,... |
| Anwendung: | WB, IHC, IF, ICC/IF, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
HG-9-91-01
Artikelnummer: Cay19179-1
HG-9-91-01 is an inhibitor of salt-inducible kinases (SIKs, IC50s = 0.92, 6.6, and 9.6 nM for SIK1, SIK2, and SIK3, respectively). It also inhibits Src, Lck, Yes, and BTK, as well as FGF and Ephrin receptors. HG-9-91-01 increases LPS-stimulated IL-10 production and suppresses pro-inflammatory cytokine secretion in...
| Schlagworte: | N-(2,4-dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-[6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-urea |
| Anwendung: | Salt-inducible kinase inhibitor |
| CAS | 1456858-58-4 |
| MW: | 567.7 D |
ab 97,00 €
Anti-SIK2
Artikelnummer: A302-676A
Protein function: Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. [The UniProt Consortium]
| Schlagworte: | Anti-SIK2, Anti-SIK-2, EC=2.7.11.1, Anti-Qin-induced kinase, Anti-Salt-inducible kinase 2, Anti-Serine/threonine-protein... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-SIK2
Artikelnummer: A302-677A
Protein function: Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. [The UniProt Consortium]
| Schlagworte: | Anti-SIK2, Anti-SIK-2, EC=2.7.11.1, Anti-Qin-induced kinase, Anti-Salt-inducible kinase 2, Anti-Serine/threonine-protein... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
SIK2, GST-tag
Artikelnummer: BPS-40264
Recombinant human QIK, full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | SIK2, SIK-2, Qin-induced kinase, Salt-inducible kinase 2, Serine/threonine-protein kinase SIK2, Serine/threonine-protein... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 150 kD |
901,00 €
Human Snf1lk2 / SIK2 ELISA Kit
Artikelnummer: G-HUFI01927.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-SIK2
Artikelnummer: ARG57588.100
Protein function: Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. [The UniProt Consortium]
| Schlagworte: | Anti-SIK2, Anti-SIK-2, EC=2.7.11.1, Anti-Qin-induced kinase, Anti-Salt-inducible kinase 2, Anti-Serine/threonine-protein... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
ARN3236
Artikelnummer: Cay31457-1
ARN3236 is an inhibitor of salt-inducible kinase 2 (SIK2, IC50 = 50s = 21.63 and 6.63 nM, respectively). It inhibits TNF-alpha secretion in RAW 264.7 cells (IC50 = ~2.5 µM) and reduces phosphorylation of the SIK2 targets CRTC3 and HDAC4 in macrophages when used at a concentration of 3 µM. ARN3236 inhibits growth of...
| Schlagworte: | 3-(2,4-dimethoxyphenyl)-4-(3-thienyl)-1H-pyrrolo[2,3-b]pyridine |
| Anwendung: | SIK2 inhibitor |
| CAS | 1613710-01-2 |
| MW: | 336.4 D |
ab 67,00 €
Anti-SIK2
Artikelnummer: ATA-HPA016026.100
Protein function: Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2)....
| Schlagworte: | Anti-SIK2, Anti-SIK-2, EC=2.7.11.1, Anti-Qin-induced kinase, Anti-Salt-inducible kinase 2, Anti-Serine/threonine-protein... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Chemi-Verse(TM) SIK2 Kinase Assay Kit
Artikelnummer: BPS-82106
The Chemi-Verse(TM) SIK2 Kinase Assay Kit is designed to measure SIK2 (salt inducible kinase 2) kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant SIK2 kinase, kinase substrate, ATP,...
| Schlagworte: | SIK2, SIK-2, Qin-induced kinase, Salt-inducible kinase 2, Serine/threonine-protein kinase SIK2, Serine/threonine-protein... |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.219,00 €
Human SIK2 (Salt Inducible Kinase 2) ELISA Kit
Artikelnummer: ELK-ELK7416.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SIK2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SIK2. Next,...
| Schlagworte: | SIK2, SIK-2, Qin-induced kinase, Salt-inducible kinase 2, Serine/threonine-protein kinase SIK2, Serine/threonine-protein... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
YKL-05-099
Artikelnummer: TGM-T17271-100mg
Description: YKL-05-099 is an inhibitor of the salt-inducible kinase(SIK1 and SIK3 , IC50s: 10 and 30 nM, respectively). It has a slightly less potent SIK2-inhibitory (IC50:40 nM). Target: SIK. Smiles: COc1ccc(nc1)N1C(=O)N(Cc2cnc(Nc3ccc(cc3OC)C3CCN(C)CC3)nc12)c1c(C)cccc1Cl. References: Sundberg TB, et al....
| Anwendung: | SIK2 inhibitor |
| CAS | 1936529-65-5 |
| MW: | 600.11 D |
ab 65,00 €