Zu "K16195" wurden 82 Artikel gefunden!
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PKR Inhibitor
Artikelnummer: Cay15323-1
The activity of double-stranded RNA-activated protein kinase (PKR) is altered by viral infection as well as by various neuropathologies. A primary phosphorylation target of PKR is eukaryotic initiation factor 2 subunit alpha (eIF2alpha), blocking translation and driving apoptosis. PKR Inhibitor is an...
| Schlagworte: | C16, GW 506033X, Protein Kinase RNA-activated, 6,8-dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one |
| Anwendung: | EIF2AK2 inhibitor |
| CAS | 608512-97-6 |
| MW: | 268.3 D |
ab 49,00 €
2-Aminopurine (hydrochloride)
Artikelnummer: Cay18609-50
2-Aminopurine is a fluorescent analog of guanosine and adenosine that is used as a site-specific probe of nucleic acid structure and dynamics. It base pairs with cytosine in a wobble configuration or with thymine in a Watson-Crick geometry. In addition to its usefulness in studies of base stacking interactions,...
| Schlagworte: | 2-AP, 9H-purin-2-amine, dihydrochloride |
| Anwendung: | EIF2AK2 inhibitor, nucleic acid structure probe |
| CAS | 1428126-74-2 |
| MW: | 208.1 D |
ab 67,00 €
Anti-PKR
Artikelnummer: ARG51245.100
Protein function: IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA...
| Schlagworte: | Anti-PKR, Anti-EIF2AK2, Anti-p68 kinase, EC=2.7.10.2, EC=2.7.11.1, Anti-Protein kinase R, Anti-eIF-2A protein kinase 2,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 471,00 €
Anti-phospho-PKR (Thr446)
Artikelnummer: ARG51761.100
Protein function: IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA...
| Schlagworte: | Anti-phospho-PKR, Anti-phospho-EIF2AK2, Anti-phospho-p68 kinase, EC=2.7.10.2, EC=2.7.11.1, Anti-phospho-Protein kinase R,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 471,00 €
Anti-phospho-PKR (Thr451)
Artikelnummer: ARG51769.100
Protein function: IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA...
| Schlagworte: | Anti-phospho-PKR, Anti-phospho-EIF2AK2, Anti-phospho-p68 kinase, EC=2.7.10.2, EC=2.7.11.1, Anti-phospho-Protein kinase R,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 471,00 €
Anti-PKR, clone 1441CT628.33.40
Artikelnummer: ARG55753.100
Protein function: IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA...
| Schlagworte: | Anti-PKR, Anti-EIF2AK2, Anti-p68 kinase, EC=2.7.10.2, EC=2.7.11.1, Anti-Protein kinase R, Anti-eIF-2A protein kinase 2,... |
| Anwendung: | ICC, IF, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
616,00 €
Anti-PKR
Artikelnummer: 600-401-DP7
Anti-PKR Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with PKR from other sources has not been determined. Protein function: IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral...
| Schlagworte: | Anti-PKR, Anti-EIF2AK2, Anti-p68 kinase, EC=2.7.11.1, EC=2.7.10.2, Anti-Protein kinase R, Anti-eIF-2A protein kinase 2,... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Anti-PKR
Artikelnummer: 600-401-DP8
Anti-PKR Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with PKR from other sources has not been determined. Protein function: IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral...
| Schlagworte: | Anti-PKR, Anti-EIF2AK2, Anti-p68 kinase, EC=2.7.11.1, EC=2.7.10.2, Anti-Protein kinase R, Anti-eIF-2A protein kinase 2,... |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Anti-EIF2AK2 / PRKR / PKR
Artikelnummer: NSJ-R31995
0.5mg/ml if reconstituted with 0.2ml sterile DI water. EIF2AK2 (Eukaryotic Translation Initiation Factor 2-Alpha Kinase 2), also called PKR, is an enzyme that in humans is encoded by the EIF2AK2 gene. Activation of EIF2AK2 allows the kinase to phosphorylate its natural substrate, the alpha subunit of eukaryotic...
| Schlagworte: | Anti-PKR, Anti-EIF2AK2, Anti-p68 kinase, EC=2.7.11.1, EC=2.7.10.2, Anti-Protein kinase R, Anti-eIF-2A protein kinase 2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-PKR
Artikelnummer: NSJ-F40174-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Interferon-induced, double-stranded RNA-activated protein kinase (PRKR/PKR) is a serine-threonine kinase. Activation by dsRNAs leads to autophosphorylation of PKR and allows the kinase to phosphorylate its natural substrate, the alpha subunit of eukaryotic protein...
| Schlagworte: | Anti-PKR, Anti-EIF2AK2, Anti-p68 kinase, EC=2.7.11.1, EC=2.7.10.2, Anti-Protein kinase R, Anti-eIF-2A protein kinase 2,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-PRKR
Artikelnummer: NSJ-F40175-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Interferon-induced, double-stranded RNA-activated protein kinase is a serine-threonine kinase. Activation by dsRNAs leads to autophosphorylation of PRKR and allows the kinase to phosphorylate its natural substrate, the alpha subunit of eukaryotic protein synthesis...
| Schlagworte: | Anti-PKR, Anti-EIF2AK2, Anti-p68 kinase, EC=2.7.11.1, EC=2.7.10.2, Anti-Protein kinase R, Anti-eIF-2A protein kinase 2,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-EIF2AK2
Artikelnummer: E-AB-16039.120
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by...
| Schlagworte: | Anti-PKR, Anti-EIF2AK2, Anti-p68 kinase, EC=2.7.10.2, EC=2.7.11.1, Anti-Protein kinase R, Anti-eIF-2A protein kinase 2,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €