Zu "K16194" wurden 18 Artikel gefunden!

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eIF2alpha Activator 2
eIF2alpha Activator 2

Artikelnummer: Cay40130-1

eIF2alpha activator 2 is an activator of eukaryotic translation initiation factor 2alpha kinase 1 (EIF2AK1), also known as heme-regulated inhibitor kinase (HRI). It activates HRI and induces eIF2alpha phosphorylation in a surrogate cell-based reporter assay. eIF2alpha activator 2 selectively inhibits the...
Schlagworte: Eukaryotic Translation Initiation Factor 2 Subunit 1 Activator 2,...
Anwendung: EIF2AK1/HRI activator
CAS 1501618-04-7
MW: 446.4 D
ab 66,00 €
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Hemin chloride
Hemin chloride

Artikelnummer: Cay16487-1

Hemin chloride is an oxidized form of heme that inhibits eukaryotic translation initiation factor 2alpha kinase 1 (eIF2alphaK1), a repressor of eIF-2alpha. This alters the initiation of mRNA translation, evoking a wide array of cellular effects. Hemin chloride is used experimentally to induce the expression of heme...
Schlagworte: (SP-5-13)-chloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,8-dipropanoato(4-)-kappaN21, kappaN22, kappaN23,...
Anwendung: EIF2AK1 inhibitor
CAS 16009-13-5
MW: 652 D
ab 66,00 €
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Anti-EIF2AK1
Anti-EIF2AK1

Artikelnummer: A302-685A

Protein function: Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser- 48' and 'Ser-51', thus preventing its recycling....
Schlagworte: Anti-HCR, Anti-HRI, Anti-PRO1362, Anti-EIF2AK1, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled...
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-EIF2AK1
Anti-EIF2AK1

Artikelnummer: A302-686A

Protein function: Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser- 48' and 'Ser-51', thus preventing its recycling....
Schlagworte: Anti-HCR, Anti-HRI, Anti-PRO1362, Anti-EIF2AK1, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled...
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-EIF2AK1
Anti-EIF2AK1

Artikelnummer: E-AB-18852.120

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Inhibits protein...
Schlagworte: Anti-HCR, Anti-HRI, Anti-EIF2AK1, Anti-PRO1362, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled...
Anwendung: WB, IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 71,00 €
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Anti-EIF2AK1
Anti-EIF2AK1

Artikelnummer: E-AB-52765.120

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Inhibits protein...
Schlagworte: Anti-HCR, Anti-HRI, Anti-EIF2AK1, Anti-PRO1362, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled...
Anwendung: WB, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 71,00 €
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Anti-EIF2AK1
Anti-EIF2AK1

Artikelnummer: G-CAB14119.100

WB 1:500 - 1:2000. Protein function: Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser- 48' and 'Ser-51', thus...
Schlagworte: Anti-HCR, Anti-HRI, Anti-EIF2AK1, Anti-PRO1362, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, rat
ab 352,00 €
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Anti-EIF2AK1
Anti-EIF2AK1

Artikelnummer: G-CAB3415.100

Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 352,00 €
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Anti-EIF2AK1
Anti-EIF2AK1

Artikelnummer: ATA-HPA016496.100

Protein function: Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to various stress conditions (PubMed:32132706, PubMed:32132707). Key activator of the integrated stress response (ISR) required for adaptation...
Schlagworte: Anti-HCR, Anti-hHRI, Anti-PRO1362, Anti-Heme-regulated inhibitor, Anti-Heme-controlled repressor, Anti-Hemin-sensitive...
Anwendung: ICC, IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: human
ab 300,00 €
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Anti-EIF2AK1
Anti-EIF2AK1

Artikelnummer: E-AB-90737.120

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Metabolic-stress...
Schlagworte: HCR, hHRI, PRO1362, Heme-regulated inhibitor, Heme-controlled repressor, Hemin-sensitive initiation factor 2-alpha kinase,...
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, rat
ab 198,00 €
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Anti-EIF2AK1 (KO Validated)
Anti-EIF2AK1 (KO Validated)

Artikelnummer: E-AB-92534.120

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Metabolic-stress...
Schlagworte: HCR, hHRI, PRO1362, Heme-regulated inhibitor, Heme-controlled repressor, Hemin-sensitive initiation factor 2-alpha kinase,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 218,00 €
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-10 %
Rabattaktion
Anti-HRI
Anti-HRI

Artikelnummer: ELK-ES2566.100

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],...
Schlagworte: Anti-HCR, Anti-hHRI, Anti-PRO1362, Anti-Heme-regulated inhibitor, Anti-Heme-controlled repressor, Anti-Hemin-sensitive...
Anwendung: WB, IHC, IF, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, monkey
169,00 € ab 152,10 €
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