Zu "K16194" wurden 32 Artikel gefunden!
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Hemin chloride
Artikelnummer: Cay16487-1
Hemin chloride is an oxidized form of heme that inhibits eukaryotic translation initiation factor 2alpha kinase 1 (eIF2alphaK1), a repressor of eIF-2alpha. This alters the initiation of mRNA translation, evoking a wide array of cellular effects. Hemin chloride is used experimentally to induce the expression of heme...
| Schlagworte: | (SP-5-13)-chloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,8-dipropanoato(4-)-kappaN21, kappaN22, kappaN23,... |
| Anwendung: | EIF2AK1 inhibitor |
| CAS | 16009-13-5 |
| MW: | 652 D |
ab 76,00 €
Anti-EIF2AK1
Artikelnummer: A302-685A
Protein function: Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser- 48' and 'Ser-51', thus preventing its recycling....
| Schlagworte: | Anti-HCR, Anti-HRI, Anti-PRO1362, Anti-EIF2AK1, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-EIF2AK1
Artikelnummer: A302-686A
Protein function: Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser- 48' and 'Ser-51', thus preventing its recycling....
| Schlagworte: | Anti-HCR, Anti-HRI, Anti-PRO1362, Anti-EIF2AK1, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-EIF2AK1
Artikelnummer: E-AB-18852.120
The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Inhibits protein...
| Schlagworte: | Anti-HCR, Anti-HRI, Anti-EIF2AK1, Anti-PRO1362, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Anti-EIF2AK1
Artikelnummer: E-AB-52765.120
The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Inhibits protein...
| Schlagworte: | Anti-HCR, Anti-HRI, Anti-EIF2AK1, Anti-PRO1362, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-EIF2AK1
Artikelnummer: ATA-HPA016496.100
Protein function: Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to various stress conditions (PubMed:32132706, PubMed:32132707). Key activator of the integrated stress response (ISR) required for adaptation...
| Schlagworte: | Anti-HCR, Anti-hHRI, Anti-PRO1362, Anti-Heme-regulated inhibitor, Anti-Heme-controlled repressor, Anti-Hemin-sensitive... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-EIF2AK1
Artikelnummer: CSB-PA002969.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-HCR, Anti-hHRI, Anti-PRO1362, Anti-Heme-regulated inhibitor, Anti-Heme-controlled repressor, Anti-Hemin-sensitive... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, monkey |
ab 126,00 €
EIF2alpha activator 2
Artikelnummer: TGM-T62637-2mg
Description: EIF2alpha activator 2 (Compound 1) is a phosphorylated activator of eukaryotic initiation factor 2alpha (eIF2alpha), exhibiting anti-proliferative effects in K562 cells (IC50: 4.79 µM) and PBMC cells (IC50: 10.52 µM). Target: Others. Smiles:...
| Anwendung: | EIF2AK1/HRI activator |
| CAS | 1501618-04-7 |
| MW: | 446.39 D |
86,00 €
eIF2alpha Activator 2
Artikelnummer: Cay40130-1
eIF2alpha activator 2 is an activator of eukaryotic translation initiation factor 2alpha kinase 1 (EIF2AK1), also known as heme-regulated inhibitor kinase (HRI). It activates HRI and induces eIF2alpha phosphorylation in a surrogate cell-based reporter assay. eIF2alpha activator 2 selectively inhibits the...
| Schlagworte: | Eukaryotic Translation Initiation Factor 2 Subunit 1 Activator 2,... |
| Anwendung: | EIF2AK1/HRI activator |
| CAS | 1501618-04-7 |
| MW: | 446.4 D |
ab 76,00 €
NEU
Anti-EIF2AK1 (KO Validated)
Artikelnummer: E-AB-92534.120
The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Metabolic-stress...
| Schlagworte: | HCR, hHRI, PRO1362, Heme-regulated inhibitor, Heme-controlled repressor, Hemin-sensitive initiation factor 2-alpha kinase,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 268,00 €
NEU
Anti-EIF2AK1
Artikelnummer: E-AB-90737.120
The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Metabolic-stress...
| Schlagworte: | HCR, hHRI, PRO1362, Heme-regulated inhibitor, Heme-controlled repressor, Hemin-sensitive initiation factor 2-alpha kinase,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 243,00 €
PhosphoSens-Red Kinase Screening Kit, - AQT0621
Artikelnummer: AQT-CSKS-AQT0621-KR-1000
PhosphoSens Sensor Peptide Substrate AQT0621 is recommended for EIF2AK1 (HRI) PhosphoSens-Red assays
| Schlagworte: | for EIF2AK1 (HRI) PhosphoSens-Red assays |
| Anwendung: | HTS, standard plate readers, hit validation, IC50 screening |
| Spezies-Reaktivität: | human |
ab 729,00 €