Zu "K16060" wurden 55 Artikel gefunden!
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Birinapant
Artikelnummer: Cay19699-5
Birinapant is a bivalent mimetic of the Diablo homolog known as second mitochondria-derived activator of caspase (Smac). It is an antagonist of cellular inhibitor of apoptosis 1 (cIAP1, or BIRC2), cIAP2 (BIRC3), and XIAP (BIRC4), binding each at nanomolar concentrations. Birinapant causes rapid cIAP1 degradation,...
| Schlagworte: | TL-32711,... |
| Anwendung: | Antineoplastic, XIAP / cIAP1 inhibitor |
| CAS | 1260251-31-7 |
| MW: | 806.9 D |
ab 77,00 €
GDC-0152
Artikelnummer: Cay17810-10
Inhibitor of apoptosis proteins (IAPs), which block various signaling pathways leading to apoptotic cell death, are commonly over-expressed in cancer cells. GDC-0152 is a potent inhibitor of specific IAPs that binds baculoviral IAP repeat (BIR) domains (Kis = 28, 14, 17, and 43 nM for XIAP BIR3, NL-IAP BIR, BIRC2...
| Schlagworte: | N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-(4-phenyl-1,2,3-thiadiazol-5-yl)-L-prolinamide |
| Anwendung: | Caspase activator |
| CAS | 873652-48-3 |
| MW: | 498.6 D |
ab 60,00 €
Birinapant, Free Base (TL-32711, CAS 1260251-31-7), >99%
Artikelnummer: LC-B-9135_10mg
Soluble in DMSO
| Schlagworte: | TL-32711,... |
| Anwendung: | Antineoplastic, XIAP / cIAP1 inhibitor |
| CAS | 1260251-31-7 |
| MW: | 806,94 D |
ab 108,00 €
Human Baculoviral IAP repeat-containing protein 2 /...
Artikelnummer: G-HUFI00959.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-cIAP
Artikelnummer: 600-401-AK2
Anti-cIAP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with cIAP from other sources has not been determined. Protein function: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and...
| Schlagworte: | Anti-API1, Anti-hIAP2, Anti-BIRC2, Anti-IAP-2, Anti-C-IAP1, Anti-hIAP-2, EC=6.3.2.-, Anti-IAP homolog B, Anti-RING finger... |
| Anwendung: | ELISA, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
684,00 €
Anti-cIAP2 / BIRC3
Artikelnummer: NSJ-R32217
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Baculoviral IAP repeat-containing protein 3 (also known as cIAP2) is a protein that in humans is encoded by the BIRC3 gene. cIAP2 is a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors...
| Schlagworte: | Anti-API2, Anti-BIRC3, Anti-hIAP1, Anti-hIAP-1, Anti-C-IAP2, EC=6.3.2.-, Anti-IAP homolog C, Anti-Apoptosis inhibitor 2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
755,00 €
Anti-BIRC3
Artikelnummer: NSJ-R36028-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Baculoviral IAP repeat-containing 3 Protein function: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic...
| Schlagworte: | Anti-API2, Anti-IAP-1, Anti-hIAP1, Anti-BIRC3, Anti-C-IAP2, Anti-hIAP-1, EC=6.3.2.-, Anti-IAP homolog C, Anti-Apoptosis... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
Anti-BIRC3
Artikelnummer: NSJ-R36100-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Baculoviral IAP repeat-containing 3 Protein function: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic...
| Schlagworte: | Anti-API2, Anti-IAP-1, Anti-hIAP1, Anti-BIRC3, Anti-C-IAP2, Anti-hIAP-1, EC=6.3.2.-, Anti-IAP homolog C, Anti-Apoptosis... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, rat |
755,00 €
Anti-cIAP1 / BIRC2
Artikelnummer: NSJ-RQ4201
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Baculoviral IAP repeat-containing protein 2 (also known as cIAP1) is a protein that in humans is encoded by the BIRC2 gene.The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor...
| Schlagworte: | Anti-API1, Anti-BIRC2, Anti-hIAP2, Anti-C-IAP1, Anti-hIAP-2, Anti-IAP homolog B, Anti-RING finger protein 48,... |
| Anwendung: | WB, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Anti-cIAP2
Artikelnummer: NSJ-F49443-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum...
| Schlagworte: | Anti-API2, Anti-IAP-1, Anti-hIAP1, Anti-BIRC3, Anti-C-IAP2, Anti-hIAP-1, EC=6.3.2.-, Anti-IAP homolog C, Anti-Apoptosis... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-cIAP1
Artikelnummer: ARG58194.100
Protein function: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling, and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and...
| Schlagworte: | Anti-API1, Anti-hIAP2, Anti-BIRC2, Anti-C-IAP1, Anti-hIAP-2, Anti-IAP homolog B, Anti-RING finger protein 48,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
Anti-BIRC2 / cIAP1
Artikelnummer: ARG58209.50
Protein function: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling, and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and...
| Schlagworte: | Anti-API1, Anti-hIAP2, Anti-BIRC2, Anti-C-IAP1, Anti-hIAP-2, Anti-IAP homolog B, Anti-RING finger protein 48,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
508,00 €