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Zu "K15409" wurden 36 Artikel gefunden!
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Artikelnummer: E-AN200125P.100
This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of...
| Schlagworte: | EC=2.7.11.1, SFRS protein kinase 1, SRSF protein kinase 1, SR-protein-specific kinase 1, Serine/arginine-rich... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
389,00 €
Artikelnummer: Cay42958-1
SPHINX is an inhibitor of serine/arginine-rich protein kinase 1 (SRPK1, IC50 = 0. µM). It is selective for SRPK1 over SRPK2 (IC50 = >10 µM). SPHINX (10 µM) inhibits EGF-induced increases in phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1) in ARPE-19 retinal epithelial cells. It decreases lesion area...
| Schlagworte: | 5-methyl-N-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]-2-furancarboxamide |
| Anwendung: | SRPK1 inhibitor |
| CAS | 848057-98-7 |
| MW: | 354.33 D |
ab 57,00 €
Artikelnummer: Cay21582-5
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1, IC50 = 5.9 nM). It is selective for SRPK1 over a panel of 50 kinases at a concentration of 1 µM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1), an SRPK1 substrate, in PC3 cells (EC50 = 360 nM) and...
| Schlagworte: | 5-(4-pyridinyl)-N-[2-[4-(2-pyridinylmethyl)-1-piperazinyl]-5-(trifluoromethyl)phenyl]-2-furancarboxamide |
| Anwendung: | SRPK1 inhibitor |
| CAS | 1818389-84-2 |
| MW: | 507.5 D |
ab 56,00 €
Artikelnummer: Cay16284-5
Serine/arginine-rich protein kinase 1 (SRPK1) targets proteins that contain multiple serine/arginine (SR) dipeptides, including SR-rich splicing factor 1, SRSF1. SRPIN340 is an isonicotinamide compound that inhibits SRPK1 (Ki = 0.89 µM). It is about 10-fold less effective against SRPK2 and does not inhibit the...
| Schlagworte: | SRPK Inhibitor, N-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide |
| Anwendung: | SRPK1 inhibitor |
| CAS | 218156-96-8 |
| MW: | 349.4 D |
ab 49,00 €
Artikelnummer: A302-461A
Protein function: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central...
| Schlagworte: | EC=2.7.11.1, Anti-SFRS protein kinase 1, Anti-SRSF protein kinase 1, Anti-SR-protein-specific kinase 1,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Artikelnummer: A302-462A
Protein function: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central...
| Schlagworte: | EC=2.7.11.1, Anti-SFRS protein kinase 1, Anti-SRSF protein kinase 1, Anti-SR-protein-specific kinase 1,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Artikelnummer: LKT-S7061.25
SRPK1 inhibitor.
| Schlagworte: | SRPIN 340 |
| Anwendung: | SRPK1 inhibitor |
| CAS | 218156-96-8 |
| MW: | 349.36 D |
ab 176,00 €
Artikelnummer: IHC-00685
Protein function: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central...
| Schlagworte: | EC=2.7.11.1, Anti-SFRS protein kinase 1, Anti-SRSF protein kinase 1, Anti-SR-protein-specific kinase 1,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Artikelnummer: E-AB-17037.120
This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of...
| Schlagworte: | EC=2.7.11.1, Anti-SRSF protein kinase 1, Anti-SFRS protein kinase 1, Anti-SR-protein-specific kinase 1,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Artikelnummer: ATA-HPA016431.100
Protein function: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central...
| Schlagworte: | EC=2.7.11.1, Anti-SRSF protein kinase 1, Anti-SFRS protein kinase 1, Anti-SR-protein-specific kinase 1,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Artikelnummer: ATA-HPA056486.100
Protein function: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central...
| Schlagworte: | EC=2.7.11.1, Anti-SRSF protein kinase 1, Anti-SFRS protein kinase 1, Anti-SR-protein-specific kinase 1,... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
463,00 €
Artikelnummer: CSB-PA029300.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SRPK1. Antigen Species: Human
| Schlagworte: | EC=2.7.11.1, Anti-SRSF protein kinase 1, Anti-SFRS protein kinase 1, Anti-SR-protein-specific kinase 1,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €