Zu "K14963" wurden 67 Artikel gefunden!
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Anti-WDR5
Artikelnummer: A302-429A
Protein function: Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic...
| Schlagworte: | Anti-WDR5, Anti-BIG3, Anti-BMP2-induced 3-kb gene protein, Anti-WD repeat-containing protein 5 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
OICR-0547
Artikelnummer: Cay18180-1
OICR-0547 is an inactive derivative of OICR-9429 (Cay-16095), an inhibitor of the protein-protein interaction between WD40 repeat protein 5 (WDR5) and mixed-lineage leukemia (MLL). It has been used as a negative control for the protein-protein inhibition activity of OICR-9429. See the Structural Genomics Consortium...
| Schlagworte: | 1,6-dihydro-N-[4-(4-morpholinyl)-3'-(4-morpholinylmethyl)[1,1'-biphenyl]-3-yl]-6-oxo-4-(trifluoromethyl)-3-pyridinecarboxa... |
| Anwendung: | Inactive OICR-9429 derivative |
| CAS | 1801873-49-3 |
| MW: | 542.6 D |
ab 44,00 €
MM-102
Artikelnummer: Cay17699-1
WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. It serves as a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3 at lysine 4 to upregulate transcription. MM-102 is a potent WDR5/MLL...
| Schlagworte: | 1-[[(2S)-5-[(aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[b... |
| Anwendung: | WDR5/MLL interaction inhibitor |
| CAS | 1417329-24-8 |
| MW: | 669.8 D |
ab 49,00 €
Anti-WDR5
Artikelnummer: A302-430A
Protein function: Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic...
| Schlagworte: | Anti-WDR5, Anti-BIG3, Anti-BMP2-induced 3-kb gene protein, Anti-WD repeat-containing protein 5 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 165,00 €
OICR-9429
Artikelnummer: Cay16095-1
WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. For example, WDR5 is a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3. WDR5 can also be a component of histone acetyltransferase...
| Schlagworte: | N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-... |
| Anwendung: | WDR5 binding inhibitor |
| CAS | 1801787-56-3 |
| MW: | 555.6 D |
ab 85,00 €
WDR5, human recombinant protein, N-terminal His-tag
Artikelnummer: BPS-71200
Human WDR5 (WD Repeat Domain 5), also known as SWD3 or BIG-3, GenBank Accession No. NM_017588, amino acids 2-334(end), with N-terminal His-tag, MW=37.5 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | WDR5, BIG3, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 37.5 kD |
693,00 €
WDR5 (human, recombinant)
Artikelnummer: Cay10944-100
WD repeats are motifs of approximately 40 amino acids typically terminating in conserved tryptophan and aspartate residues. Several WD40 repeats combine to form the structural WD domain. Such an arrangement facilitates protein-protein interactions allowing the formation of multiprotein complexes. Human WDR5 contains...
| Schlagworte: | BIG3, BMP2-induced 3-kb Gene Protein, SWD3, Set1c WD40 repeat protein, homolog, WD-Repeat Protein 5 |
| Anwendung: | Enzyme activity |
| Exprimiert in: | E.coli |
| MW: | 34,4 kD |
554,00 €
WDR5-0103
Artikelnummer: Cay13945-1
WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. For example, WDR5 is a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3. WDR5 can also be a component of histone acetyltransferase...
| Schlagworte: | WD-Repeat Protein 5-0103, 3-[(3-methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-benzoic acid, methyl ester |
| Anwendung: | MLL core complex inhibitor |
| CAS | 890190-22-4 |
| MW: | 383.4 D |
ab 38,00 €
Anti-WDR5
Artikelnummer: BPS-25321
.
| Schlagworte: | Anti-WDR5, Anti-BIG3, Anti-BMP2-induced 3-kb gene protein, Anti-WD repeat-containing protein 5, |
| Anwendung: | ELISA, WB |
| Spezies-Reaktivität: | human |
742,00 €
WDR5, FLAG-tag
Artikelnummer: BPS-51111
Human WDR5 (WD Repeat Domain 5), also known as SWD3 or BIG-3, GenBank Accession No. NM_017588, a.a. 2-334(end), with N-terminal FLAG-tag, MW=37 kDa, expressed in a baculovirus-infected Sf9 insect expression system.
| Schlagworte: | WDR5, BIG3, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 37 kD |
693,00 €
WDR5, His-Tag, Biotin-Labeled
Artikelnummer: BPS-80016-1
Human WDR5 (WD Repeat Domain 5), also known as SWD3 or BIG-3, GenBank Accession No. NM_017588, a.a. 2-334(end), with N-terminal Avi-His-tag, MW=39 kDa, expressed in Sf9 insect cells via a baculovirus expression system. This protein is enzymatically biotinylated using Avi-Tag(TM) technology. Biotinylation is...
| Schlagworte: | WDR5, BIG3, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 39 kD |
ab 468,00 €
Anti-Wdr5
Artikelnummer: 100-401-V89
Anti-Wdr5 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with Wdr5 from other species not tested. Protein function: Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'....
| Schlagworte: | Anti-WDR5, Anti-BIG3, Anti-BMP2-induced 3-kb gene protein, Anti-WD repeat-containing protein 5 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
690,00 €