Zu "K14463" wurden 28 Artikel gefunden!
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SLX-4090
Artikelnummer: Cay41979-1
SLX-4090 is an inhibitor of microsomal triglyceride transfer protein (MTTP, IC50 = 8 nM). It selectively inhibits MTTP-mediated secretion of apolipoprotein B (ApoB) over ApoA1 in primary human hepatocytes (IC50s = 81 and >30,000 nM, respectively). In vivo, SLX-4090 reduces postprandial increases in serum...
| Schlagworte: | 3,4-dihydro-6-[[[6-methoxy-4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-2(1H)-isoquinolinecarboxylic acid,... |
| Anwendung: | MTTP inhibitor |
| CAS | 913541-47-6 |
| MW: | 546.54 D |
ab 58,00 €
Lomitapide
Artikelnummer: Cay10009610-1
Lomitapide is an inhibitor of microsomal triglyceride transfer protein (MTTP, IC50 = 0.5 nM in a triglyceride transfer assay). It inhibits apolipoprotein B (ApoB) secretion in HepG2 cells (EC50 = 0.8 nM). Lomitapide inhibits triglyceride secretion in fasted rats (ED50 = 0.19 mg/kg, p.o.) and reduces total plasma...
| Schlagworte: | AEGR 773, BMS 201038,... |
| Anwendung: | MTTP inhibitor |
| CAS | 182431-12-5 |
| MW: | 693.7 D |
ab 49,00 €
Anti-MTTP
Artikelnummer: ARG55650.100
Protein function: Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:25108285, PubMed:22236406). Required for the secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:23475612,...
| Schlagworte: | Anti-MTP, Anti-MTTP, Anti-Microsomal triglyceride transfer protein large subunit |
| Anwendung: | ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
707,00 €
Anti-MTTP
Artikelnummer: ARG55716.100
Protein function: Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:25108285, PubMed:22236406). Required for the secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:23475612,...
| Schlagworte: | Anti-MTP, Anti-MTTP, Anti-Microsomal triglyceride transfer protein large subunit |
| Anwendung: | FC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Human Microsomal triglyceride transfer protein large...
Artikelnummer: G-HUFI01017.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Mouse Microsomal triglyceride transfer protein large...
Artikelnummer: G-MOFI00352.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Lomitapide-d8
Artikelnummer: Cay28764-1
Lomitapide-d8 is intended for use as an internal standard for the quantification of lomitapide (Cay-10009610) by GC- or LC-MS. Lomitapide is an inhibitor of microsomal triglyceride transfer protein (MTTP, IC50 = 0.5 nM in a triglyceride transfer assay). It inhibits apolipoprotein B (ApoB) secretion in HepG2 cells...
| Schlagworte: | N-(2,2,2-trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl-d8]-9H-fl... |
| Anwendung: | GC-MS, LC-MS, internal standard, MTTP inhibitor |
| CAS | 2459377-96-7 |
| MW: | 701.8 D |
ab 325,00 €
CP 346,086
Artikelnummer: Cay39156-1
CP 346,086 is an inhibitor of microsomal triglyceride transfer protein (MTTP, IC50 = 2 nM). It inhibits apolipoprotein B (ApoB) and triglyceride secretion in HepG2 cells (IC50 = 2.6 nM for both). CP 346,086 (10 mg/kg) lowers plasma triglyceride levels, as well as plasma total, VLDL, and LDL cholesterol levels in...
| Schlagworte: | N-[1,2,3,4-tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)- [1,1'-biphenyl]-2-carboxamide |
| Anwendung: | MTTP (microsomal triglyceride transfer protein) inhibitor |
| CAS | 186390-48-7 |
| MW: | 477.5 D |
ab 40,00 €
Mouse MTTP (Microsomal Triglyceride Transfer Protein)...
Artikelnummer: ELK-ELK6302.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse MTTP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse MTTP. Next,...
| Schlagworte: | Mtp, Mttp, Microsomal triglyceride transfer protein large subunit |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
Rat MTTP (Microsomal Triglyceride Transfer Protein) ELISA...
Artikelnummer: ELK-ELK7480.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat MTTP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat MTTP. Next,...
| Schlagworte: | Mtp, Mttp, Microsomal triglyceride transfer protein large subunit |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 374,00 €
Anti-MTTP / MTP
Artikelnummer: NSJ-RQ5538
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Microsomal triglyceride transfer protein large subunit is a protein that in humans is encoded by the MTTP gene. It is mapped to 4q23. MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI)...
| Schlagworte: | Anti-MTP, Anti-MTTP, Anti-Microsomal triglyceride transfer protein large subunit, MTTP Antibody / MTP |
| Anwendung: | WB, IF, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Dirlotapide
Artikelnummer: TGM-T15006-100mg
Description: Dirlotapide (CP742033) is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food intake in a dose-dependent manner, possibly by increasing the release of peptide YY into the circulation. Target: CETP, Others....
| Schlagworte: | Slentrol, CP742033 |
| Anwendung: | Targets microsomal triglyceride transfer protein large subunit (MTTP, MTP) |
| CAS | 481658-94-0 |
| MW: | 674.71 D |
ab 710,00 €