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Ezetimibe
Ezetimibe

Artikelnummer: Cay16331-25

Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes.Upon oral administration ezetimibe undergoes rapid glucuronidation in the intestine where its glucuronide binds...
Schlagworte: Ezetrol, SCH 58235, (3R,4S)-1,4-fluorophenyl-3-[(3S-3-4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone
Anwendung: NPC1L1 inhibitor, Intestinal cholesterol absorption inhibitor
CAS 163222-33-1
MW: 409.4 D
ab 74,00 €
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Ezetimibe-d4
Ezetimibe-d4

Artikelnummer: Cay25044-1

Ezetimibe-d4 is intended for use as an internal standard for the quantification of ezetimibe (Cay-16331) by GC- or LC-MS. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of...
Schlagworte: Ezetrol-d4,...
Anwendung: Internal standard, GC-MS, LC-MS
CAS 1093659-89-2
MW: 413.5 D
494,00 €
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Anti-NPC1L1
Anti-NPC1L1

Artikelnummer: G-CAB10049.100

Anwendung: WB
Reaktivität: Human
314,00 €
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Ezetimibe
Ezetimibe

Artikelnummer: BPS-27749-2

Ezetimibe is an anti-hyperlipidemic medication which is used to lower cholesterol levels. Specifically, it appears to bind to a critical mediator of cholesterol absorption, the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelial cells as well as in hepatocytes.
Schlagworte: ezetimibe, Zetia, (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Anwendung: Cholesterol absorption inhibitor, NPC1L1 inhibitor
MW: 409.4 D
ab 308,00 €
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NPC1L1, Human NPC1 (Niemann-Pick disease, type C1, gene)-like 1, Real Time PCR Primer Set
NPC1L1, Human NPC1 (Niemann-Pick disease, type C1,...

Artikelnummer: VHPS-6284

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: NPC1L1, Niemann-Pick C1-like protein 1
Anwendung: RNA quantification
45,00 €
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Npc1L1, Mouse NPC1-like 1, Real Time PCR Primer Set
Npc1L1, Mouse NPC1-like 1, Real Time PCR Primer Set

Artikelnummer: VMPS-4302

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: Npc1l1, Niemann-Pick C1-like protein 1
Anwendung: RNA quantification
45,00 €
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Anti-NPC1L1, NT (NPC1L1, Niemann-Pick C1-like protein 1)
Anti-NPC1L1, NT (NPC1L1, Niemann-Pick C1-like protein 1)

Artikelnummer: 039084.200

The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up...
Schlagworte: Anti-NPC1L1, Anti-Niemann-Pick C1-like protein 1
Anwendung: ELISA, WB
Reaktivität: Human
582,00 €
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Anti-NPC1L1, NT (NPC1L1, Niemann-Pick C1-like protein 1) (Azide free) (APC)
Anti-NPC1L1, NT (NPC1L1, Niemann-Pick C1-like protein 1)...

Artikelnummer: 039084-APC.200

The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up...
Schlagworte: Anti-NPC1L1, Anti-Niemann-Pick C1-like protein 1
Anwendung: FLISA, WB
Reaktivität: Human
721,00 €
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Anti-NPC1L1, NT (NPC1L1, Niemann-Pick C1-like protein 1) (Azide Free) (Biotin)
Anti-NPC1L1, NT (NPC1L1, Niemann-Pick C1-like protein 1)...

Artikelnummer: 039084-Biotin.200

The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up...
Schlagworte: Anti-NPC1L1, Anti-Niemann-Pick C1-like protein 1
Anwendung: ELISA, WB
Reaktivität: Human
721,00 €
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Anti-NPC1L1, NT (NPC1L1, Niemann-Pick C1-like protein 1) (Azide free) (FITC)
Anti-NPC1L1, NT (NPC1L1, Niemann-Pick C1-like protein 1)...

Artikelnummer: 039084-FITC.200

The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up...
Schlagworte: Anti-NPC1L1, Anti-Niemann-Pick C1-like protein 1
Anwendung: FLISA, WB
Reaktivität: Human
721,00 €
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Anti-NPC1L1, NT (NPC1L1, Niemann-Pick C1-like protein 1) (Azide free) (HRP)
Anti-NPC1L1, NT (NPC1L1, Niemann-Pick C1-like protein 1)...

Artikelnummer: 039084-HRP.200

The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up...
Schlagworte: Anti-NPC1L1, Anti-Niemann-Pick C1-like protein 1
Anwendung: ELISA, WB
Reaktivität: Human
721,00 €
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Anti-Niemann-Pick Disease, Type C1 Gene-Like 1 (NPC1L1, Niemann-Pick C1-like Protein 1, NPC1 like 1,
Anti-Niemann-Pick Disease, Type C1 Gene-Like 1 (NPC1L1,...

Artikelnummer: N2566-32B.100

Dietary consumption and intestinal cholesterol absorption contribute to plasma cholesterol levels, which factor into the risk of coronary heart disease. Niemann-Pick type C1 Like 1 protein (NPC1L1 or NPC3) is enriched in the small intestine and is found in the brush border membrane of enterocytes. It plays a...
Schlagworte: Anti-Npc1l1, Anti-Niemann-Pick C1-like protein 1
Anwendung: ICC, IF, IHC, WB
Reaktivität: Human, Mouse, Swine, Rat
498,00 €
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