Zu "K14426" wurden 30 Artikel gefunden!
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Hydrochlorothiazide-3,3-d2
Artikelnummer: Cay39983-1
Hydrochlorothiazide-3,3-d2 is intended for use as an internal standard for the quantification of hydrochlorothiazide (Cay-21304) by GC- or LC-MS. Hydrochlorothiazide is a thiazide diuretic that inhibits the apical membrane sodium chloride cotransporter in the distal and collecting duct nephron segments.Formal Name:...
| Schlagworte: | HCTZ-3,3-d2, HCTZ-d2, 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-d2, 1,1-dioxide |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, thiazide diuretic |
| CAS | 1219798-89-6 |
| MW: | 299.8 D |
ab 133,00 €
Human NCCT (Na-Cl Cotransporter) ELISA Kit
Artikelnummer: ELK-ELK3971.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NCCT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NCCT. Next,...
| Schlagworte: | NCC, Na-Cl symporter, Na-Cl cotransporter, Solute carrier family 12 member 3, Thiazide-sensitive sodium-chloride... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Indapamide
Artikelnummer: Cay21308-1
Indapamide (Cay-21308) is an analytical reference standard that is categorized as a sulfonamide diuretic that blocks delayed-rectifier potassium currents. Formulations containing indapamide are used to treat hypertension, but it is abused by athletes to reduce body weight rapidly or mask the presence of other...
| Schlagworte: | (±)-Indapamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-benzamide |
| Anwendung: | Analytical reference standard, Sulfonamide diuretic, Na+-Cl- symport inhibitor |
| CAS | 26807-65-8 |
| MW: | 365.8 D |
ab 60,00 €
Hydrochlorothiazide
Artikelnummer: Cay22671-1
Hydrochlorothiazide (Cay-22671) is an analytical reference standard categorized as a thiazide diuretic. Diuretics, including hydrochlorothiazide, have been misused in sports for weight reduction and as masking agents. This product is intended for use in analytical forensic applications. A general research tool is...
| Schlagworte: | HCTZ, NSC 53477, SU 5879, 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide |
| Anwendung: | Analytical reference standard, Thiazide diuretic |
| CAS | 58-93-5 |
| MW: | 297.7 D |
ab 66,00 €
Chlorothiazide
Artikelnummer: Cay26300-10
Chlorothiazide (Cay-26300) is an analytical reference standard categorized as a thiazide diuretic. Diuretics, including chlorothiazide, have been used as masking agents in sports doping. This product is intended for analytical forensic applications. This product is also available as a general research tool...
| Schlagworte: | NSC 25693, 6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide |
| Anwendung: | Analytical reference standard, Thiazide diuretic, Na+-Cl- symport inhibitor |
| CAS | 58-94-6 |
| MW: | 295.7 D |
ab 60,00 €
Metolazone
Artikelnummer: Cay26304-1
Metolazone (Cay-26304) is an analytical reference standard categorized as a diuretic. It has been detected as an adverse analytical finding (AAF) during anti-doping testing. This product is intended for use in analytical forensic applications. This product is also available as a general research tool...
| Schlagworte: | SR 720-22, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide |
| Anwendung: | Analytical reference standard, Diuretic, Na+-Cl- symport inhibitor |
| CAS | 17560-51-9 |
| MW: | 365.8 D |
ab 77,00 €
Metolazone
Artikelnummer: Cay15987-10
Metolazone is a thiazide-like diuretic. It inhibits the Na+/Cl- cotransporter (IC50 = 0.3 µM for the rat transporter) and human carbonic anhydrase VII (CAVII), CAXII, and CAXIII (Kis = 2.1, 5.4, and 15 nM, respectively). Metolazone (0.3 and 1 mg/kg) induces fluid loss and enhances captopril-induced decreases in...
| Schlagworte: | SR 720-22, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide |
| Anwendung: | Na+-Cl- symport / SLC12A3 inhibitor |
| CAS | 17560-51-9 |
| MW: | 365.8 D |
ab 43,00 €
Chlorthalidone
Artikelnummer: Cay16213-10
Chlorthalidone is a thiazide-like diuretic that inhibits the Na+/Cl- cotransporter in the distal convoluted tubule of the kidney, which prevents reabsorption of sodium and chloride leading to a reduction in plasma volume and cardiac output. It also inhibits carbonic anhydrase (CA), including the isoforms CAVB, VII,...
| Schlagworte: | Hygroton, NSC 69200, Oradil, Thalitone(R), 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)-benzenesulfonamide |
| Anwendung: | SLC12A3 / Sodium/chloride cotransporter inhibitor |
| CAS | 77-36-1 |
| MW: | 338.8 D |
ab 66,00 €
Anti-SLC12A3 / NCC
Artikelnummer: ARG22199.50
Protein function: Electroneutral sodium and chloride ion cotransporter. In kidney distal convoluted tubules, key mediator of sodium and chloride reabsorption (PubMed:8021284). Receptor for the proinflammatory cytokine IL18. Contributes to IL18-induced cytokine production, including IFNG, IL6, IL18 and CCL2, either...
| Schlagworte: | Anti-Tsc, Anti-Slc12a3, Anti-Na-Cl symporter, Anti-Solute carrier family 12 member 3, Anti-Thiazide-sensitive... |
| Anwendung: | WB, IHC, ICC, IF, EM |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | dog, human, mouse, rat |
520,00 €
Hydrochlorothiazide
Artikelnummer: LKT-H9614.100
A thiazide diuretic commonly used as an antihypertensive. A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and...
| Anwendung: | Na+-Cl- symport inhibitor |
| CAS | 58-93-5 |
| MW: | 297.74 D |
ab 72,00 €
Hydrochlorothiazide
Artikelnummer: Cay21304-1
Hydrochlorothiazide (HCTZ) is a thiazide diuretic that inhibits the apical membrane sodium chloride cotransporter in the distal and collecting duct nephron segments.Formal Name: 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide. CAS Number: 58-93-5. Synonyms: HCTZ, NSC 53477, SU 5879....
| Schlagworte: | HCTZ, NSC 53477, SU 5879, 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide |
| Anwendung: | Diuretic, Na+-Cl- symport inhibitor |
| CAS | 58-93-5 |
| MW: | 297.7 D |
ab 43,00 €
Hydrochlorothiazide Impurity C
Artikelnummer: Cay22384-1
Hydrochlorothiazide impurity C is a potential impurity found in commercial hydrochlorothiazide preparations. Hydrochlorothiazide (Cay-21304) is a thiazide diuretic that inhibits the apical membrane sodium chloride cotransporter in the distal and collecting duct nephron segments.Formal Name:...
| Schlagworte: | N-[[7-(aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxido-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4... |
| Anwendung: | Impurity |
| CAS | 402824-96-8 |
| MW: | 607.5 D |
ab 159,00 €