Zu "K14342" wurden 27 Artikel gefunden!
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Elobixibat
Artikelnummer: TGM-T15209-100mg
Description: Elobixibat (A 3309) is an inhibitor of the ileal bile acid transporter (IC50: 0.13 nM, 0.53 nM, and 5.8 nM for mouse, human, and canine IBAT). Elobixibat can be used in studies about chronic idiopathic constipation. Target: Others. Smiles:...
| Schlagworte: | AZD 7806, A 3309 |
| Anwendung: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
| CAS | 439087-18-0 |
| MW: | 695.89 D |
ab 98,00 €
Odevixibat
Artikelnummer: TGM-T16376-100mg
Description: Odevixibat (A4250) is an effective, selective and orally active ileal bile acid transporter inhibitor. Odevixibat has the potential for the treatment of primary biliary cirrhosis. Odevixibat reduces cholestatic liver and bile duct injury in mice model. Target: Others. Smiles:...
| Schlagworte: | A4250 |
| Anwendung: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
| CAS | 501692-44-0 |
| MW: | 740.93 D |
ab 31,00 €
Maralixibat Chloride
Artikelnummer: TGM-T32873-100mg
Description: Maralixibat Chloride (LUM001 chloride), an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation. Target: Potassium Channel. Smiles: [Cl-].CCCCC1(CCCC)CS(=O)(=O)c2ccc(cc2[C@H]([C@H]1O)c1ccc(OCc2ccc(C[N+]34CCN(CC3)CC4)cc2)cc1)N(C)C. References: Kurata,...
| Schlagworte: | SHP-625, SHP625, Livmarli, LUM001 chloride, Lopixibat chloride, Lopixibat, SHP 625, SHP625 chloride |
| Anwendung: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
| CAS | 228113-66-4 |
| MW: | 710.41 D |
ab 261,00 €
Ganglioside GM1 Mixture (ovine) (ammonium salt)
Artikelnummer: TGM-T37582-1mg
Description: Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane.3It associates with growth factor receptors,...
| Anwendung: | Monosialylated gangliosides |
| CAS | 1007119-81-4 |
| MW: | 1563.9 D |
ab 297,00 €
Linerixibat
Artikelnummer: TGM-T3978-10mg
Description: Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM) that can lower glucose in an animal model of type 2 diabetes and demonstrates excellent developability properties. Target: HBV. Smiles:...
| Schlagworte: | Iinerixibat, GSK2330672 |
| Anwendung: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
| CAS | 1345982-69-5 |
| MW: | 546.68 D |
ab 75,00 €
Anti-SLC10A2
Artikelnummer: CSB-PA843819.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-IBAT, Anti-ISBT, Anti-ASBT, Anti-SLC10A2, Anti-Solute carrier family 10 member 2, Anti-Ileal Na(+)/bile acid... |
| Anwendung: | ELISA, WB, |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-Slc10a2, C-terminal
Artikelnummer: ARG64665.100
Protein function: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism. [The UniProt Consortium]
| Schlagworte: | Anti-ISBT, Anti-IBAT, Anti-ASBT, Anti-Ntcp2, Anti-Slc10a2, Anti-Solute carrier family 10 member 2, Anti-Ileal Na(+)/bile... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
822,00 €
Anti-SLC10A2 / ASBT, C-terminal
Artikelnummer: ARG64875.100
Protein function: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism. [The UniProt Consortium]
| Schlagworte: | Anti-ISBT, Anti-IBAT, Anti-ASBT, Anti-SLC10A2, Anti-Solute carrier family 10 member 2, Anti-Ileal Na(+)/bile acid... |
| Anwendung: | ELISA, IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
822,00 €
Anti-Slc10a2
Artikelnummer: NSJ-R33430-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide.
| Schlagworte: | Anti-IBAT, Anti-ASBT, Anti-ISBT, Anti-Ntcp2, Anti-Slc10a2, Anti-Solute carrier family 10 member 2, Anti-Ileal Na(+)/bile... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
790,00 €
Anti-SLC10A2
Artikelnummer: NSJ-R36375-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Solute carrier family 10 (sodium/bile acid cotransporter family), member 2, ASBT Protein function: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the...
| Schlagworte: | Anti-IBAT, Anti-ASBT, Anti-ISBT, Anti-SLC10A2, Anti-Solute carrier family 10 member 2, Anti-Ileal Na(+)/bile acid... |
| Anwendung: | IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
790,00 €
GSK2330672
Artikelnummer: Cay23843-1
GSK2330672 is an inhibitor of the sodium/bile acid and sulfated solute cotransporter (ASBT, IC50s = 42, 2.1, and 1.9 nM for human, mouse, and rat ASBT, respectively). In vivo, GSK2330672 (0.05 mg/kg) stimulates fecal bile acid secretion, reduces hemoglobin A1c (HbA1c) and plasma glucose levels, and increases total...
| Schlagworte: | 3-[[[(3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4-benzothiazepin-8-yl]methyl]amino]-penta... |
| Anwendung: | SLC10A2 / ASBT inhibitor |
| CAS | 1345982-69-5 |
| MW: | 546.7 D |
ab 150,00 €
Anti-SLC10A2
Artikelnummer: ATA-HPA004795.100
Protein function: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity...
| Schlagworte: | Anti-ASBT, Anti-IBAT, Anti-ISBT, Anti-SLC10A2, Anti-Solute carrier family 10 member 2, Anti-Ileal Na(+)/bile acid... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €