Zu "K14165" wurden 160 Artikel gefunden!
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Alexidine (hydrochloride)
Artikelnummer: Cay13876-10
Alexidine is an alkyl bis(biguanide) antiseptic which has been used in mouthwashes to eliminate plaque forming microorganisms. It binds to lipopolysaccharide and lipoteichoic acid and inhibits fungal phospholipase B (IC50 ~ 250 nM). Alexidine also inhibits the mitochondrial phosphatase PTPMT1 (IC50 = 1.08 µM, in...
| Schlagworte: | N1,N14-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide, dihydrochloride |
| Anwendung: | Antiseptic |
| CAS | 1715-30-6 |
| MW: | 581.7 D |
ab 43,00 €
Anti-Laforin, clone k2A3
Artikelnummer: ARG56966.50
Protein function: Has both dual-specificity protein phosphatase and glucan phosphatase activities. Together with the E3 ubiquitin ligase NHLRC1/malin, appears to be involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. Dephosphorylates phosphotyrosine, phosphoserine and...
| Schlagworte: | Anti-EPM2A, Anti-Laforin, Anti-LAFPTPase, EC=3.1.3.-, EC=3.1.3.16, EC=3.1.3.48, Anti-Lafora PTPase, Anti-Glucan phosphatase |
| Anwendung: | WB, FC, ICC, IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
488,00 €
Anti-Laforin (isoform a), Internal
Artikelnummer: ARG64831.100
Protein function: Has both dual-specificity protein phosphatase and glucan phosphatase activities. Together with the E3 ubiquitin ligase NHLRC1/malin, appears to be involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. Dephosphorylates phosphotyrosine, phosphoserine and...
| Schlagworte: | Anti-EPM2A, Anti-Laforin, Anti-LAFPTPase, EC=3.1.3.-, EC=3.1.3.48, EC=3.1.3.16, Anti-Lafora PTPase, Anti-Glucan phosphatase |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
784,00 €
Anti-DUSP13
Artikelnummer: NSJ-N1141-100UG
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. DUSP13 is a dual specificity phosphatase (DSP), dephosphorylating tyrosine and serine/threonine residues, and is expressed in two forms. DUSP13B, or testis and skeletal muscle-specific dual specificity phosphatase (TMDP), has been shown inhibit MAPK...
| Schlagworte: | Anti-BEDP, Anti-MDSP, Anti-DUSP13, Anti-DUSP13A, EC=3.1.3.16, EC=3.1.3.48, Anti-Muscle-restricted DSP,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 317,00 €
Anti-Laforin
Artikelnummer: NSJ-R33718-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: EPM2A, EPM2A Protein function: Has both dual-specificity protein phosphatase and glucan phosphatase activities. Together with the E3 ubiquitin ligase NHLRC1/malin, appears to be involved in the...
| Schlagworte: | Anti-EPM2A, Anti-Laforin, Anti-LAFPTPase, EC=3.1.3.-, EC=3.1.3.48, EC=3.1.3.16, Anti-Lafora PTPase, Anti-Glucan... |
| Anwendung: | WB, IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
Anti-DUSP23
Artikelnummer: E-AB-14964.120
Dual specificity protein phosphatase 23, also known as low molecular mass dual specificity phosphatase 3 (LDP-3), is an enzyme that in humans is encoded by the DUSP23 gene. Protein function: Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can...
| Schlagworte: | Anti-LDP3, Anti-LDP-3, Anti-DUSP23, EC=3.1.3.16, EC=3.1.3.48, Anti-VH1-like phosphatase Z, Anti-Dual specificity protein... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
Anti-DUSP11
Artikelnummer: E-AB-17232.120
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase...
| Schlagworte: | Anti-PIR1, Anti-DUSP11, EC=3.1.3.-, Anti-Dual specificity protein phosphatase 11, Anti-RNA/RNP complex-1-interacting... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 71,00 €
Anti-DUSP13
Artikelnummer: NSJ-F40047-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity...
| Schlagworte: | Anti-BEDP, Anti-MDSP, Anti-DUSP13, Anti-DUSP13A, EC=3.1.3.48, EC=3.1.3.16, Anti-Muscle-restricted DSP,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-DUSP22
Artikelnummer: E-AB-14065.120
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase...
| Schlagworte: | Anti-JSP1, Anti-JSP-1, Anti-MKP-x, Anti-DUSP22, Anti-LMW-DSP2, EC=3.1.3.16, EC=3.1.3.48, Anti-MAP kinase phosphatase x,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
Anti-DUSP26
Artikelnummer: E-AB-11170.120
DUSP26, also designated LDP4, MKP8, NATA1 and SKRP3, is ubiquitously expressed in brain except in the hippocampus. DUSP26 dephosphorylates p38 thereby inhibiting p38-mediated apoptosis in anaplastic thyroid cancer cells. Downregulation of DUSP26 may also contribute to malignant phenotypes of glioma. Protein...
| Schlagworte: | Anti-DSP-4, Anti-LDP-4, Anti-MKP-8, Anti-DUSP26, Anti-DUSP24, EC=3.1.3.16, EC=3.1.3.48, Anti-MAP kinase phosphatase 8,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-DUSP26
Artikelnummer: E-AB-14965.120
DUSP26, also designated LDP4, MKP8, NATA1 and SKRP3, is ubiquitously expressed in brain except in the hippocampus. DUSP26 dephosphorylates p38 thereby inhibiting p38-mediated apoptosis in anaplastic thyroid cancer cells. Downregulation of DUSP26 may also contribute to malignant phenotypes of glioma. Protein...
| Schlagworte: | Anti-DSP-4, Anti-LDP-4, Anti-MKP-8, Anti-DUSP26, Anti-DUSP24, EC=3.1.3.16, EC=3.1.3.48, Anti-MAP kinase phosphatase 8,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-DUSP15
Artikelnummer: NSJ-F40176-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. DUSP15 belongs to the non-receptor class of the protein-tyrosine phosphatase family. This protein has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase.
| Schlagworte: | EC=3.1.3.48, EC=3.1.3.16, Anti-VH1-related member Y, Anti-Dual specificity protein phosphatase 15, Anti-Vaccinia virus... |
| Anwendung: | IHC, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €