Zu "K13869" wurden 31 Artikel gefunden!
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HEK293T/Human SLC7A11 & SLC3A2 Stable Cell Line
Artikelnummer: CSB-SC5338HU.1
Tag Info: C-terminal Flag-tagged & C-terminal 6xHis-tagged. Selection Marker: Puromycin & Blasticidin. Buffer: 35% FBS + 55% DMEM + 10% DMSO. Culture Medium: DMEM + 10% FBS + 2 µg/mL Puromycin +2 µg/mL Blasticidin. Growth Properties: DMEM + 10% FBS + 2 µg/mL Puromycin +2 µg/mL Blasticidin. Protein function:...
| Schlagworte: | xCT, SLC7A11, Cystine/glutamate transporter, Amino acid transport system xc-, Solute carrier family 7 member 11, Calcium... |
| Anwendung: | Binding assay, FC, cell based ELISA. |
| Wirt: | Human cells |
| Spezies-Reaktivität: | human |
8.895,00 €
Imidazole ketone erastin
Artikelnummer: TGM-T5523-100mg
Description: Imidazole ketone erastin (IKE) is an ferroptosis inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and lipid peroxidation. Target: Ferroptosis. Smiles:...
| Schlagworte: | IKE |
| Anwendung: | Ferroptosis inducer, probable Cystine/glutamate transporter inhibitor |
| CAS | 1801530-11-9 |
| MW: | 655.14 D |
ab 71,00 €
SLC7A11 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-03750-100ug
Description: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
| Schlagworte: | Amino acid transport system xc-, xCT, Cystine/glutamate transporter, SLC7A11, Solute carrier family 7 member 11, Calcium... |
| MW: | 58.2 kD |
ab 2.202,00 €
Imidazole Ketone Erastin
Artikelnummer: Cay27088-10
Imidazole ketone erastin is an inducer of ferroptosis. It inhibits glutamate release in human CCF-STTG1 astrocytoma cells (IC50 = 30 nM), indicating inhibition of the system xc- cystine/glutamate transporter. Imidazole ketone erastin increases production of lipid reactive oxygen species (ROS) in SUDHL6 diffuse large...
| Schlagworte: | IKE,... |
| Anwendung: | Ferroptosis inducer, probable Cystine/glutamate transporter inhibitor |
| CAS | 1801530-11-9 |
| MW: | 655.1 D |
ab 128,00 €
Erastin2
Artikelnummer: TGM-T35994-100mg
Target: Ferroptosis. Smiles: CC(C)Oc1ccc(cc1-n1c(CN2CCN(CC2)C(=O)COc2ccc(Cl)cc2)nc2ccccc2c1=O)-c1ccccc1. References: Cao, J.Y., Poddar, A., Magtanong, L., et al. A genome-wide haploid genetic screen identifies regulators of glutathione abundance and ferroptosis sensitivity. Cell Rep. 26(6), 1544-1556 (2019).
| Schlagworte: | 35MEW28 |
| Anwendung: | Ferroptosis inducer, cystine/glutamate transporter inhibitor |
| CAS | 1695533-44-8 |
| MW: | 623.14 D |
ab 67,00 €
Human SLC7A11 Protein, hFc Tag
Artikelnummer: DIM-PME100572.10
Recombinant Human SLC7A11 Protein with C-terminal human Fc tag. SLC7A11(Lys67-Gly74) (Leu151-Cys158) (Lys215-Thr233) (Thr219-Leu317) (Asp386-Ser387) (Ser445-Pro447) hFc(Glu99-Ala330), Protein function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine...
| Schlagworte: | CCBR1, xCT |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 33.4 kD |
ab 103,00 €
SLC7A11 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100048.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | xCT, SLC7A11, Cystine/glutamate transporter, Amino acid transport system xc-, Solute carrier family 7 member 11, Calcium... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 55.4 kD |
ab 1.291,00 €
Anti-SLC7A11
Artikelnummer: CSB-PA145393.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SLC7A11. Antigen Species: Human
| Schlagworte: | Anti-xCT, Anti-SLC7A11, Anti-Cystine/glutamate transporter, Anti-Amino acid transport system xc-, Anti-Solute carrier... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Erastin2
Artikelnummer: Cay27087-1
Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter. It inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 µM). It induces cell death in HAP1 cells when used at a concentration of 5 µM, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1...
| Schlagworte: | 35MEW28,... |
| Anwendung: | Ferroptosis inducer, cystine/glutamate transporter inhibitor |
| CAS | 1695533-44-8 |
| MW: | 623.1 D |
ab 111,00 €
Anti-SLC7A11, Internal
Artikelnummer: ARG64200.100
Protein function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. [The UniProt Consortium]
| Schlagworte: | Anti-xCT, Anti-SLC7A11, Anti-Cystine/glutamate transporter, Anti-Amino acid transport system xc-, Anti-Solute carrier... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, rat |
822,00 €
Human SLC7A11 / XCT ELISA Kit
Artikelnummer: G-HUFI00981.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-xCT
Artikelnummer: 600-401-GU3
This affinity purified antibody is directed against human xCT. This product was affinity purified from monospecific antiserum by immunoaffinity purification. Blast analysis of the sequence of the immunogen shows 100% identity with human and orangutan, and 88% identity to mouse. Protein function: Sodium-independent,...
| Schlagworte: | Anti-xCT, Anti-SLC7A11, Anti-Cystine/glutamate transporter, Anti-Amino acid transport system xc-, Anti-Solute carrier... |
| Anwendung: | ELISA, FC, IHC, IFM, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
719,00 €