Zu "K13869" wurden 19 Artikel gefunden!
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NEU
FA16
Artikelnummer: Cay40499-1
FA16 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter. It reduces the viability of various cancer cell lines, including HT-1080 fibrosarcoma and A375 melanoma cells (IC50s = 1.26 and 2.31 µM, respectively), 786-O renal cell carcinoma cells (IC50 = 0.7 µM), and MDA-MB-231...
| Schlagworte: | N,N-dimethyl-4-(4-((2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)methyl)piperidin-1-yl)benzenesulfonamide |
| Anwendung: | Ferroptosis inducer , system xc- cystine/glutamate transporter (SLC7A11) inhibitor |
| MW: | 466.5 D |
ab 39,00 €
Human SLC7A11 (Solute Carrier Family 7, Member 11) ELISA Kit
Artikelnummer: ELK-ELK5319.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SLC7A11. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SLC7A11....
| Schlagworte: | xCT, Cystine/glutamate transporter, Amino acid transport system xc-, Solute carrier family 7 member 11, Calcium channel... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Imidazole Ketone Erastin
Artikelnummer: Cay27088-10
Imidazole ketone erastin is an inducer of ferroptosis. It inhibits glutamate release in human CCF-STTG1 astrocytoma cells (IC50 = 30 nM), indicating inhibition of the system xc- cystine/glutamate transporter. Imidazole ketone erastin increases production of lipid reactive oxygen species (ROS) in SUDHL6 diffuse large...
| Schlagworte: | IKE,... |
| Anwendung: | Ferroptosis inducer, Probable Cystine/glutamate transporter inhibitor |
| CAS | 1801530-11-9 |
| MW: | 655.1 D |
ab 125,00 €
Erastin2
Artikelnummer: Cay27087-1
Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter. It inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 µM). It induces cell death in HAP1 cells when used at a concentration of 5 µM, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1...
| Schlagworte: | 35MEW28,... |
| Anwendung: | Ferroptosis inducer, Cystine/glutamate transporter inhibitor |
| CAS | 1695533-44-8 |
| MW: | 623.1 D |
ab 109,00 €
Anti-SLC7A11, Internal
Artikelnummer: ARG64200.100
Protein function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. [The UniProt Consortium]
| Schlagworte: | Anti-xCT, Anti-SLC7A11, Anti-Cystine/glutamate transporter, Anti-Amino acid transport system xc-, Anti-Solute carrier... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, rat |
784,00 €
Human SLC7A11 / XCT ELISA Kit
Artikelnummer: G-HUFI00981.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-xCT
Artikelnummer: 600-401-GU3
This affinity purified antibody is directed against human xCT. This product was affinity purified from monospecific antiserum by immunoaffinity purification. Blast analysis of the sequence of the immunogen shows 100% identity with human and orangutan, and 88% identity to mouse. Protein function: Sodium-independent,...
| Schlagworte: | Anti-xCT, Anti-SLC7A11, Anti-Cystine/glutamate transporter, Anti-Amino acid transport system xc-, Anti-Solute carrier... |
| Anwendung: | ELISA, FC, IHC, IFM, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
684,00 €
Anti-xCT
Artikelnummer: 600-401-GU3S
This affinity purified antibody is directed against human xCT. This product was affinity purified from monospecific antiserum by immunoaffinity purification. Blast analysis of the sequence of the immunogen shows 100% identity with human and orangutan, and 88% identity to mouse. Protein function: Sodium-independent,...
| Schlagworte: | Anti-xCT, Anti-SLC7A11, Anti-Cystine/glutamate transporter, Anti-Amino acid transport system xc-, Anti-Solute carrier... |
| Anwendung: | ELISA, FC, IHC, IFM, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
180,00 €
Anti-XCT
Artikelnummer: NSJ-R34450-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Solute carrier family 7 (cationic amino acid transporter, y+ system) member 11, SLC7A11 Protein function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity...
| Schlagworte: | Anti-xCT, Anti-SLC7A11, Anti-Cystine/glutamate transporter, Anti-Amino acid transport system xc-, Anti-Solute carrier... |
| Anwendung: | WB, ELISA (peptide), IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, rat |
755,00 €
Anti-SLC7A11 / xCT
Artikelnummer: ARG57998.100
Protein function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. [The UniProt Consortium]
| Schlagworte: | Anti-xCT, Anti-SLC7A11, Anti-Cystine/glutamate transporter, Anti-Amino acid transport system xc-, Anti-Solute carrier... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
624,00 €
Anti-SLC7A11
Artikelnummer: E-AB-17625.120
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant...
| Schlagworte: | Anti-xCT, Anti-SLC7A11, Anti-Cystine/glutamate transporter, Anti-Amino acid transport system xc-, Anti-Solute carrier... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
Anti-SLC7A11/xCT
Artikelnummer: E-AB-93104.120
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant...
| Schlagworte: | xCT, Cystine/glutamate transporter, Amino acid transport system xc-, Solute carrier family 7 member 11, Calcium channel... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €