Zu "K13761" wurden 39 Artikel gefunden!
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Osoresnontrine
Artikelnummer: TGM-T8515-100mg
Description: Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory. Target: PDE. Smiles: O=c1nc(Cc2ccccn2)[nH]c2n(ncc12)C1CCOCC1. References: Cornelia Dorner-Ciossek, R. Giovannini, Holger Rosenbrock. BI 409306, A NOVEL PHOSPHODIE STERASE 9A INHIBITOR,...
| Schlagworte: | BI-409306 |
| Anwendung: | Potent, selective PDE9A inhibitor |
| CAS | 1189767-28-9 |
| MW: | 311.34 D |
ab 33,00 €
PDE9A Protein, Human, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-01467-100ug
Description: PDE9A Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
| Schlagworte: | PDE9A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A |
| MW: | 76.0 kD |
ab 236,00 €
PDE9A Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPH-02706-100ug
Description: PDE9A Protein, Mouse, Recombinant (His) is expressed in E. coli.
| Schlagworte: | Pde9a, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A |
| MW: | 65.7 kD |
ab 359,00 €
PDE9A Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-01921-100ug
Description: PDE9A Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 40 kDa and the accession number is O76083-2.
| Schlagworte: | phosphodiesterase 9A, HSPDE9A2 |
| MW: | 40 kD |
699,00 €
PDE9A Protein, Human, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-01922-100ug
Description: PDE9A Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.5 kDa and the accession number is O76083-2.
| Schlagworte: | HSPDE9A2, phosphodiesterase 9A |
| MW: | 89.5 kD |
699,00 €
PDE-9 inhibitor
Artikelnummer: TGM-T12389-100mg
Description: PDE-9 inhibitor is used for treatment neurodegenerative diseases. Target: Others. Smiles: C[C@@H]1CN(Cc2ccccc2)C[C@H]1c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
| Anwendung: | PDE9 inhibitor |
| CAS | 1082743-70-1 |
| MW: | 393.48 D |
ab 140,00 €
PF-04447943
Artikelnummer: TGM-T16478-10mg
Description: PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits anti-inflammatory activity, attenuates inflammatory responses by inhibiting...
| Schlagworte: | PF04447943, Edelinontrine, PF 04447943 |
| Anwendung: | PDE9A inhibitor |
| CAS | 1082744-20-4 |
| MW: | 395.46 D |
ab 74,00 €
Tovinontrine
Artikelnummer: TGM-T61833-10mg
Description: Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment. It exhibits high efficacy, with IC 50 values of 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively [1]. Target: PDE. Smiles:...
| Schlagworte: | IMR-687 |
| Anwendung: | Targets high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35] (PDE9) |
| CAS | 2062661-53-2 |
| MW: | 394.47 D |
ab 105,00 €
High affinity cGMP-specific 3',5'-cyclic...
Artikelnummer: CSB-EP527985HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-593aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MGSGSSSYRP KAIYLDIDGR IQKVIFSKYC NSSDIMDLFC IATGLPRNTT ISLLTTDDAM VSIDPTMPAN SERTPYKVRP VAIKQLSAGV EDKRTTSRGQ SAERPLRDRR...
| Schlagworte: | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, Recombinant Human High affinity cGMP-specific 3',5'-cyclic... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 76.0 kD |
ab 247,00 €
High affinity cGMP-specific 3,5-cyclic phosphodiesterase...
Artikelnummer: CSB-EP530347MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-534aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MGAGSSSYRP KAIYLDIDGR IQKVVFSKYC NSSDIMDLFC IATGLPRNTT ISLLTTDDAM VSIDPTMPAN SERTPYKVRP VAVKQVSERE ELIQGVLAQV AEQFSRAFKI NELKAEVANH LAVLEKRVEL...
| Schlagworte: | Pde8b, Pde9a, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, Recombinant Mouse High affinity cGMP-specific... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 65.7 kD |
ab 364,00 €
PF-04447943
Artikelnummer: Cay24299-25
PF-04447943 is a brain-permeable phosphodiesterase (PDE) inhibitor that is selective for PDE9A (IC50 = 12 nM) over other PDEs (IC50s = >940 nM) in enzymatic assays of second messenger hydrolysis. It is over 1,000-fold more selective for PDE9A over 79 non-PDE targets, with the exception of the melatonin MT3/ML2...
| Schlagworte: | 1,5-dihydro-6-[(3S,4S)-4-methyl-1-(2-pyrimidinylmethyl)-3-pyrrolidinyl]-1-(tetrahydro-2H-pyran-4-yl)-4H-pyrazolo[3,4-d]pyr... |
| Anwendung: | PDE9A inhibitor |
| CAS | 1082744-20-4 |
| MW: | 395.5 D |
ab 49,00 €
Anti-PDE9A
Artikelnummer: ARG10812.50
Protein function: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755,...
| Schlagworte: | Anti-High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A |
| Anwendung: | IF, ELISA, ICC, IF, IHC, IP, WB, DB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
608,00 €