Zu "K13700" wurden 25 Artikel gefunden!
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KT182
Artikelnummer: TGM-T11784-100mg
Description: KT182 is a selective and potent inhibitor of alpha/beta-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells. Target: MAGL. Smiles: OCc1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1. References: Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas...
| Anwendung: | ABHD6 inhibitor |
| CAS | 1402612-62-7 |
| MW: | 438.52 D |
ab 40,00 €
JZP-430
Artikelnummer: TGM-T15635-100mg
Description: JZP-430 is an effective, highly selective, irreversible inhibitor of alpha/beta-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL). Target: MAGL, Lipase. Smiles: CN(C1CCCCCCC1)C(=O)Oc1nsnc1N1CCOCC1....
| Anwendung: | ABHD6 inhibitor |
| CAS | 1672691-74-5 |
| MW: | 354.47 D |
ab 60,00 €
KT185
Artikelnummer: TGM-T15668-10mg
Description: KT185 is an orally-bioavailable and brain-penetrant ABHD6 inhibitor (IC50: 0.21 nM in Neuro2A cells). Target: Others. Smiles: O=C(N1CCCCC1)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1. References: Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective,...
| Anwendung: | ABHD6 inhibitor |
| CAS | 1472640-86-0 |
| MW: | 519.64 D |
ab 233,00 €
Anti-ABHD6
Artikelnummer: CSB-PA000792.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-Monoacylglycerol lipase ABHD6, Anti-2-arachidonoylglycerol hydrolase, Anti-Abhydrolase domain-containing protein 6,... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-ABHD6
Artikelnummer: CSB-PA449719.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-Monoacylglycerol lipase ABHD6, Anti-2-arachidonoylglycerol hydrolase, Anti-Abhydrolase domain-containing protein 6,... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €
WWL70
Artikelnummer: Cay10011213-10
WWL70 is an inhibitor of alpha/beta-hydrolase domain-containing protein 6 (ABHD6, IC50 = 70 nM). It increases the expression of the adipose browning-related gene Ucp1 in differentiated 3T3-L1 mouse adipocytes and increases the oxygen consumption rate (OCR), an effect that can be blocked by the PPARalpha antagonist...
| Schlagworte: | N-methyl-N-[[3-(4-pyridinyl)phenyl]methyl]-carbamic acid, 4'-(aminocarbonyl)[1,1'-biphenyl]-4-yl ester |
| Anwendung: | ABHD6 inhibitor |
| CAS | 947669-91-2 |
| MW: | 437.5 D |
ab 62,00 €
KT195
Artikelnummer: Cay14818-1
The serine hydrolase known as alpha/beta-hydrolase domain-containing protein 6 (ABHD6) hydrolyzes 2-arachidonoyl glycerol (2-AG, Cay-62160) to regulate its availability at cannabinoid receptors. KT195 is a selective inhibitor of ABHD6 (IC50 = 10 nM) with negligible activity against other serine hydrolases such as...
| Schlagworte: | ML-295, [4-(4'-methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-methanone |
| Anwendung: | ABHD6 inhibitor |
| CAS | 1402612-58-1 |
| MW: | 438.5 D |
ab 44,00 €
JZP 430
Artikelnummer: Cay35383-5
JZP 430 is an inhibitor of alpha/beta-hydrolase domain-containing protein 6 (ABHD6, IC50 = 0.044 for the human enzyme). It is selective for ABHD6 over fatty acid amid hydrolase (FAAH) and monoacylglycerol lipase (MAGL) when used at a concentration of 2.5 µM, ABHD12 at 1 µM, as well as lysosomal acid lipase (LAL) and...
| Schlagworte: | N-cyclooctyl-N-methyl-carbamic acid, 4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl ester |
| Anwendung: | ABHD6 inhibitor |
| CAS | 1672691-74-5 |
| MW: | 354.5 D |
ab 166,00 €
KT203
Artikelnummer: Cay14819-5
KT203 is a potent inhibitor of alpha/beta-hydrolase domain-containing protein 6 (ABHD6) with IC50 values of 0.82, 3.9, and 0.31 nM using Neuro2A membrane proteomes, recombinant ABHD6 in HEK293T cells, and Neuro2A cells in situ, respectively. Following administration of KT203 (1 mg/kg, i.p.) in mice, ABHD6 is...
| Schlagworte: | ML-296, 4'-[1-[[2-(phenylmethyl)-1-piperidinyl]carbonyl]-1H-1,2,3-triazol-4-yl]-[1,1'-biphenyl]-3-carboxylic acid |
| Anwendung: | ABHD6 inhibitor |
| CAS | 1402612-64-9 |
| MW: | 466.5 D |
ab 52,00 €
KT182
Artikelnummer: Cay15404-5
KT182 is a potent inhibitor of alpha/beta-hydrolase domain-containing protein 6 (ABHD6) with IC50 values of 1.7, 15.1, and 0.24 nM using Neuro2a membrane proteomes, recombinant ABHD6 in HEK293T cells, and Neuro2a cells in situ, respectively. Following administration of KT182 (1 mg/kg, i.p.) in mice, ABHD6 is...
| Schlagworte: | [4-[3'-(hydroxymethyl)[1,1'-biphenyl]-4-yl]-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-methanone |
| Anwendung: | ABHD6 inhibitor |
| CAS | 1402612-62-7 |
| MW: | 438.5 D |
ab 52,00 €
WWL123
Artikelnummer: Cay16849-1
The serine hydrolase known as alpha/beta-hydrolase domain-containing protein 6 (ABHD6) hydrolyzes 2-arachidonoyl glycerol (Cay-62160) to regulate its availability at cannabinoid receptors. WWL123 is a brain-penetrant inhibitor of ABHD6 (IC50 = 0.43 µM) that demonstrates >10-fold selectivity for ABHD6 compared to a...
| Schlagworte: | N-([1,1'-biphenyl]-3-ylmethyl)-N-methyl-carbamic acid, 4'-(aminocarbonyl)[1,1'-biphenyl]-4-yl ester |
| Anwendung: | ABHD6 inhibitor |
| CAS | 1338574-83-6 |
| MW: | 436.5 D |
ab 62,00 €
WWL70
Artikelnummer: LKT-W894440.1
ABHD6 inhibitor.
| Schlagworte: | [4-(4-carbamoylphenyl)phenyl] N-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate |
| Anwendung: | ABHD6 inhibitor |
| CAS | 947669-91-2 |
| MW: | 437.5 D |
ab 119,00 €