Zu "K13525" wurden 116 Artikel gefunden!
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NEU
Anti-Recombinant VCP, clone C111933
Artikelnummer: E-AN302313L.100
Protein function: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles...
| Schlagworte: | Anti-VCP, Anti-Valosin-containing protein, Anti-15S Mg(2+)-ATPase p97 subunit, Anti-Transitional endoplasmic reticulum... |
| Anwendung: | WB, IHC, IF, IP, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
NEU
Anti-Recombinant VCP, clone C113194
Artikelnummer: E-AN303574L.100
Protein function: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles...
| Schlagworte: | Anti-VCP, Anti-Valosin-containing protein, Anti-15S Mg(2+)-ATPase p97 subunit, Anti-Transitional endoplasmic reticulum... |
| Anwendung: | WB, IHC, ICC/IF, FCM, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
NEU
CB-5339
Artikelnummer: Cay46233-10
CB-5339 is an inhibitor of the AAA-ATPase p97, also known as valosin-containing protein (VCP, IC50 = 9 nM), and a derivative of CB-5083 (Cay-19311). It inhibits phosphodiesterase 6C (PDE6C) and accumulates in rat retina to a lesser extent than CB-5083. CB-5339 inhibits the growth of 16 primary acute myeloid leukemia...
| Schlagworte: | 2-methyl-1-[5,6,7,8-tetrahydro-4-[(phenylmethyl)amino]pyrido[2,3-d]pyrimidin-2-yl]-1H-indole-4-carboxamide |
| Anwendung: | ATPase p97/VCP inhibitor |
| CAS | 1863952-15-1 |
| MW: | 412.5 D |
ab 105,00 €
Anti-VCP
Artikelnummer: A300-589A
Protein function: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles...
| Schlagworte: | Anti-VCP, Anti-TER ATPase, EC=3.6.4.6, Anti-Valosin-containing protein, Anti-15S Mg(2+)-ATPase p97 subunit,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
CB-5083
Artikelnummer: Cay19311-1
CB-5083 is an orally bioavailable inhibitor of p97 (IC50 = 11 nM), a transitional endoplasmic reticulum ATPase also known as valosin-containing protein (VCP). It disrupts cellular protein homeostasis and demonstrates anti-tumor activity in hematological and solid tumor models. CB-5083 causes accumulation of...
| Schlagworte: | 1-[7,8-dihydro-4-[(phenylmethyl)amino]-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide |
| Anwendung: | p97 inhibitor |
| CAS | 1542705-92-9 |
| MW: | 413.5 D |
ab 69,00 €
Anti-Zebrafish Cdc48 / Valosin-containing protein / Vcp
Artikelnummer: NSJ-RZ1323
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Zebrafish Cdc48, also known as cell division cycle 48, is a crucial ATPase that is involved in various cellular processes including protein degradation, cell cycle regulation, and membrane dynamics. Cdc48 is part of the AAA+ ATPase family and functions as a part...
| Schlagworte: | Anti-vcp, Anti-Protein CDC48, Anti-Valosin-containing protein, Anti-Transitional endoplasmic reticulum ATPase, Zebrafish... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
Anti-VCP
Artikelnummer: A300-588A
Protein function: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles...
| Schlagworte: | Anti-VCP, Anti-TER ATPase, EC=3.6.4.6, Anti-Valosin-containing protein, Anti-15S Mg(2+)-ATPase p97 subunit,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
NMS-873
Artikelnummer: Cay17674-1
The p97 AAA (ATPase associated with diverse cellular activities) is a ubiquitin-selective chaperone known to play a critical role in the degradation of misfolded membrane and secretory proteins and has been linked to various cellular processes that require unfolding and disassembly of protein complexes....
| Schlagworte: | VCP Inhibitor III,... |
| Anwendung: | VCP inhibitor |
| CAS | 1418013-75-8 |
| MW: | 520.7 D |
ab 59,00 €
DBeQ
Artikelnummer: Cay15318-5
The ATPase p97 is an ubiquitin-selective chaperone known to play a critical role in the degradation of misfolded membrane and secretory proteins and has been linked to various cellular processes that require unfolding and disassembly of protein complexes. DBeQ is a selective, reversible, and ATP-competitive...
| Schlagworte: | JRF 12, N,N'-Dibenzylquinazoline-2,4-diamine, N2,N4-bis(phenylmethyl)-2,4-quinazolinediamine |
| Anwendung: | ATPase p97 inhibitor |
| CAS | 177355-84-9 |
| MW: | 340.4 D |
ab 133,00 €
KUS121
Artikelnummer: TGM-T36570-5mg
Description: KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, an inducer of ER stress, in HeLa cells when used at concentrations of 20, 50, and 50...
| Anwendung: | VCP modulator |
| CAS | 1357164-52-3 |
| MW: | 459.45 D |
ab 467,00 €
CB-5083
Artikelnummer: TGM-T6796-1mg
Description: CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM). Target: p97. Smiles: Cc1cc2c(cccc2n1-c1nc2CCOCc2c(NCc2ccccc2)n1)C(N)=O. References: Zhou HJ, et al. J Med Chem. 2015, 58(24), 9480-9497.
| Schlagworte: | CB5083, CB 5083 |
| Anwendung: | p97 inhibitor |
| CAS | 1542705-92-9 |
| MW: | 413.47 D |
ab 37,00 €
Anti-VCP, clone 1344CT150.163.114
Artikelnummer: ARG55819.100
Protein function: Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles...
| Schlagworte: | Anti-VCP, Anti-TER ATPase, EC=3.6.4.6, Anti-Valosin-containing protein, Anti-15S Mg(2+)-ATPase p97 subunit,... |
| Anwendung: | ICC, IF, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
616,00 €